Results 41 to 50 of about 6,464 (211)

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

Anidulafungin in combination with amphotericin B against Aspergillus fumigatus. [PDF]

, 2009
We investigated the effects of anidulafungin alone and in combination with amphotericin B against Aspergillus fumigatus. Indifference was the only type of interaction observed in vitro. Anidulafungin at 1 and 5 mg/kg of body weight/day, amphotericin B at
C. Loretelli, Loretelli, Cristian, G. Scalise, Barchiesi, F., E. Spreghini, Manso, Esther, Pisa, Eleonora, Spreghini, E, Santinelli, A, Scalise, Giorgio, F. Barchiesi, Milici, Maria Eleonara, Manso,E, Orlando, Fiorenza, MILICI, Maria Eleonora, Pisa, E, E. Manso, Loretelli, C, E. Pisa, Barchiesi, Francesco, F. Orlando, A. Santinelli, M. E. Milici, Spreghini, Elisabetta, Santinelli, Alfredo, Orlando, F, Scalise, G   +26 more
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From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez, Marcella Vieira Ambrosio, Marcela Eduarda Olegario Fernandes, Ewerton Garcia de Oliveira Mima   +3 more
wiley   +1 more source

In vitro effectiveness of Anidulafungin against Candida sp. biofilms [PDF]

, 2013
This study furnishes deeper insights to previous works on anidulafungin, demonstrating the potent activity against Candida strains planktonic cells and biofilms.
Carone A, MONTAGNA, Maria Teresa, Piarulli M, CAGGIANO, GIUSEPPINA, CATALANO, ALESSIA, Schiavone BP, CAROCCI, ALESSIA, CORBO, Filomena Faustina Rina, CARRIERI, Antonio, FRANCHINI, Carlo, ROSATO, Antonio   +10 more
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A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, Volume 13, Issue 41, 22 July 2026.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Low but Sufficient Anidulafungin Exposure in Critically Ill Patients [PDF]

, 2014
The efficacy of anidulafungin is driven by the area under the concentration-time curve (AUC)/MIC ratio. Patients in intensive care may be at risk for underexposure. In critically ill patients with an invasive Candida infection, the anidulafungin exposure
Alffenaar, Jan-Willem C., Werf, van der, Tjip S., Zijlstra, Jan G.; id_orcid, Uges, Donald R. A., Kosterink, Jos G. W.; id_orcid, van Wanrooy, Marjolijn J. P., Kosterink, Jos G. W., Arends, Jan P., Zijlstra, Jan G., Rodgers, Michael G. G.   +9 more
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Invasive Candidiasis in Infants and Children: Recent Advances in Epidemiology, Diagnosis, and Treatment

Journal of Fungi, 2019
This paper reviews recent advances in three selected areas of pediatric invasive candidiasis: epidemiology, diagnosis, and treatment. Although the epidemiological trends of pediatric invasive candidiasis illustrate a declining incidence, this infection ...
Thomas J. Walsh, Aspasia Katragkou, Tempe Chen, Christine M. Salvatore, Emmanuel Roilides   +4 more
doaj   +1 more source

Anidulafungin Treatment Blocks the Sexual Cycle of Pneumocystis murina and Prevents Growth and Survival without Rescue by an Alternative Mode of Replication

Microbiology Spectrum, 2022
The proposed life cycle of fungi in the genus Pneumocystis has typically included both an asexual cycle via binary fission and a sexual cycle. Until recently, the strategy used for sexual replication was largely unknown, but genomic and functional assays
Melanie T. Cushion, Alan Ashbaugh, Steven G. Sayson, Christopher Mosley, Philippe M. Hauser   +4 more
doaj   +1 more source

Combination Antifungal Therapy and Formulary Optimization for Progressive Invasive Pulmonary Aspergillosis in a Pediatric Patient With Acute Myeloid Leukemia: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Therapeutic response in refractory invasive pulmonary aspergillosis may depend not only on antifungal class escalation, but also on formulation choice. In this complex pediatric acute myeloid leukemia (AML) case, radiologic improvement followed combination therapy and switch to brand‐name liposomal amphotericin B, underscoring the importance ...
Faryal Khamis, Amal Al Busaidi, Kawther Al Bahrani, Asia Al‐Rashdi   +3 more
wiley   +1 more source

Antifungal activity and killing kinetics of anidulafungin, caspofungin and amphotericin B against Candida auris [PDF]

, 2019
DigitalBackground: Candida auris is an emerging MDR pathogen. It shows reduced susceptibility to azole drugs and, in some strains, high amphotericin B MICs have been described. For these reasons, echinocandins were proposed as first-line treatment for C.
Morales López, Soraya, Gamarra, Soledad, Theill, Laura, Macedo, Daiana, Dudiuk, Catiana, Leonardelli, Florencia, Rodríguez, José-Yesid, Berrio, Indira, Salcedo, Soraya, Marín, Adriana, Garcia Effron, Guillermo   +10 more
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