Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh +13 more
wiley +1 more source
The graphical abstract summarizes the laboratory characterization of Naganishia uzbekistanensis strain CY11558. The isolate shows distinct colony morphology, globular yeast cells with a fibrillar surface network under scanning electron microscopy, and a weakly positive cryptococcal antigen reaction.
Xin Fan +7 more
wiley +1 more source
Anidulafungin for Neonatal Hematogenous Candida Meningoencephalitis: Identification of Candidate Regimens for Humans Using a Translational Pharmacological Approach [PDF]
Hematogenous Candida meningoencephalitis (HCME) is a serious infection in premature neonates. Anidulafungin is an echinocandin antifungal agent with potent activity against Candida spp., but its efficacy ...
Peter A. Warn +22 more
core +1 more source
Anidulafungin liposome nanoparticles exhibit antifungal activity against planktonic and biofilm Candida albicans [PDF]
Fungal infections can cause significant patient morbidity and mortality. Nanoparticle therapeutics have the potential to improve treatment of these infections.
Luc Langlois +13 more
core +1 more source
Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi +3 more
wiley +1 more source
Anidulafungin increases the antibacterial activity of tigecycline in polymicrobial Candida albicans/Staphylococcus aureus biofilms on intraperitoneally implanted foreign bodies [PDF]
Objectives: We aimed to establish a novel murine intra-abdominal foreign body infection model to study the activity of anidulafungin and tigecycline against dual species Candida albicans/Staphylococcus aureus biofilms.
Rogiers, Ona +15 more
core +1 more source
Recent Insights into the Paradoxical Effect of Echinocandins
Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj +1 more source
Phylogenetic Profiling of the Diabetic Foot Ulcer Microbiome of an Afro‐Caribbean Population
Illumina amplicon sequencing revealed diverse bacterial and fungal communities in chronic diabetic foot ulcers (DFUs) and adjacent normal skin from Afro‐Caribbean patients. Corynebacterium striatum dominated both sites. DFUs had higher relative abundance of Pseudomonas aeruginosa and the antifungal‐resistant Candida duobushaemulonii, with significantly
Nkemcho Ojeh +9 more
wiley +1 more source
Effect of protein binding on the activity of voriconazole alone or combined with anidulafungin against Aspergillus spp. using a time-kill methodology [PDF]
Objectives: the aims of the study were to explore the activity of total and free (according to protein binding) maximal concentrations achieved in serum after multiple doses of voriconazole 400/200 mg and anidulafungin 200/100 mg against Aspergillus ...
Alou Cervera, Luis +7 more
core
A Comparative Study of the Effects of Intravitreal Anidulafungin, Voriconazole, and Amphotericin B in an Experimental Candida Endophthalmitis Model [PDF]
Purpose: To compare the safety and efficacy of intravitreal anidulafungin injection with voriconazole and amphotericin B (Amp B) in an experimental Candida endophthalmitis (CE) model.Methods: Intravitreal 1 x 10(5) CFU/0.1 ml Candida albicans was ...
Uyanık, Muhammet Hamidullah +7 more
core +1 more source

