Results 71 to 80 of about 6,415 (210)

Multiple-dose pharmacokinetics of anidulafungin during continuous venovenous haemofiltration

, 2011
Background: Clinical studies support a role for anidulafungin as first-line treatment of invasive candidiasis in critically ill patients and postulate no need for dose adjustments in mild to severe renal failure.
Meyer, Brigitte (Medizinische Universität Wien), Thalhammer, Florian (Universitätsklinik für Innere Medizin I), Böhmdorfer, Michaela (University of Vienna), Zuba, Clara (Medizinische Universität Wien), Fuhrmann, Valentin (University of Vienna), Jäger, Walter (University of Vienna), Leitner, Judith M. (Medizinische Universität Wien), Saria, Katrin (Medizinische Universität Wien)   +7 more
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Micafungin versus anidulafungin in critically ill patients with invasive candidiasis: A retrospective study [PDF]

, 2016
_Background:_ In critically ill patients the incidence of invasive fungal infections caused by Candida spp. has increased remarkably. Echinocandins are recommended as initial treatment for invasive fungal infections. The safety and efficacy of micafungin
Geest, Patrick, Groeneveld, A.B.J. (Johan), Patrick J. van der Geest, Ladage, S.E. (Sophie E.), Ladage, Sophie, Geest, P.J. (Patrick) van der, Hunfeld, Nicole, Groeneveld, Johan, Sophie E. Ladage, A. B. Johan Groeneveld, Hunfeld, N.G.M. (Nicole), Nicole G. M. Hunfeld   +11 more
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Malignant Otitis Externa in Central Australia: A 15‐Year Retrospective Review Between 2009 and 2024

Medical Journal of Australia, Volume 224, Issue 3, March 2026.
ABSTRACT We performed a 15‐year retrospective audit of all cases of malignant otitis externa (MOE) referred to Alice Springs Hospital in Central Australia from 2009 to 2024, the largest Australian series of MOE. Data on demographics, risk factors, microbiological culture results, management and outcomes were collected, identifying 64 cases of MOE, with
George P. Drewett, Mini Jacob, Belle Culhane, Amy Booth, Connor Wright, Sajan Thomas, Anjali Abraham   +6 more
wiley   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Experience of using anidulafungin for treatment of invasive candidosis in patients after liver transplantation

Трансплантология (Москва), 2016
This article is an example of a successful treatment invasive fungal infections and bacterial infections caused by multidrug-resistant pathogen after liver ...
M. Sh. Khubutiya, N. K. Kuznetsova, S. V. Zhuravel, T. V. Chernenkaya, M. S. Novruzbekov, A. I. Bazhenov, I. I. Goncharova   +6 more
doaj  

Effectiveness and safety of echinocandins combination therapy with the standard of care compared to the standard of care monotherapy for the treatment of invasive aspergillosis infection: a meta-analysis

Frontiers in Pharmacology
BackgroundThis meta-analysis aims to evaluate the effectiveness and safety of combining echinocandins with standard of care (SOC) antifungal drugs for treating invasive aspergillosis infection (IAI).MethodWe searched PubMed, Embase, and Cochrane Library ...
Yazed Saleh Alsowaida, Bader Alshoumr, Shuroug A. Alowais, Khalid Bin Saleh, Alia Alshammari, Kareemah Alshurtan, Haytham A. Wali   +6 more
doaj   +1 more source

In vitro effectiveness of Anidulafungin against Candida sp. biofilms

, 2013
This study furnishes deeper insights to previous works on anidulafungin, demonstrating the potent activity against Candida strains planktonic cells and biofilms.
Carone A, MONTAGNA, Maria Teresa, Piarulli M, CAGGIANO, GIUSEPPINA, CATALANO, ALESSIA, Schiavone BP, CAROCCI, ALESSIA, CORBO, Filomena Faustina Rina, CARRIERI, Antonio, FRANCHINI, Carlo, ROSATO, Antonio   +10 more
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Acute Liver Failure With Transient Liver Steatosis Following Multiple Hits Postoperatively in a Patient With Limb‐Girdle Muscular Dystrophy: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Transient liver steatosis is rarely described. A fast development of liver steatosis leading to acute liver failure (ALF) is, to our knowledge, rarely observed. It is so far observed and published in acute fatty liver of pregnancy, and in a few cases of ALF. However, it is observed in elective surgery for pancreaticoduodenectomy and some cases
Anders Benjamin Kildal, Espen Molden, Elisabeth Myrseth, Didrik Kjønås, Gunnar Oltmanns, Rasmus Goll, Kim Erlend Mortensen, Geir Ivar Nedredal   +7 more
wiley   +1 more source

Low but Sufficient Anidulafungin Exposure in Critically Ill Patients

, 2014
The efficacy of anidulafungin is driven by the area under the concentration-time curve (AUC)/MIC ratio. Patients in intensive care may be at risk for underexposure. In critically ill patients with an invasive Candida infection, the anidulafungin exposure
Alffenaar, Jan-Willem C., Werf, van der, Tjip S., Zijlstra, Jan G.; id_orcid, Uges, Donald R. A., Kosterink, Jos G. W.; id_orcid, van Wanrooy, Marjolijn J. P., Kosterink, Jos G. W., Arends, Jan P., Zijlstra, Jan G., Rodgers, Michael G. G.   +9 more
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Efficacy, Safety and Biological Characteristics of Formulation Based on Essential Oil Against Co‐Infections of Herpes Simplex Virus‐1 and Candida albicans

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Essential oils with anti‐HSV‐1 activity were identified through literature review and tested against Candida to develop a formulation for co‐infections. The blend was assessed for anti‐inflammatory properties, allergenic potential via standardized BAT, and overall antiviral efficacy.
Maura Di Vito, Domiziana Coggiatti, Marilena La Sorda, Stefania Garzoli, Giulia Lombardini, Debora Talamonti, Scilla Pizzarelli, Abdesselam Zhiri, Margherita Cacaci, Riccardo Torelli, Maurizio Sanguinetti, Francesca Bugli   +11 more
wiley   +1 more source