Results 91 to 100 of about 6,869 (208)

A Comparative Study of the Effects of Intravitreal Anidulafungin, Voriconazole, and Amphotericin B in an Experimental Candida Endophthalmitis Model

, 2017
Purpose: To compare the safety and efficacy of intravitreal anidulafungin injection with voriconazole and amphotericin B (Amp B) in an experimental Candida endophthalmitis (CE) model.Methods: Intravitreal 1 x 10(5) CFU/0.1 ml Candida albicans was ...
Uyanık, Muhammet Hamidullah, Yavan, Ibrahim, Karagoz, Ergenekon, Çadırcı, Elif, Turhan, Vedat, Duzgun, Eyup, Uğan, Rüstem Anıl, Keleş, Sadullah   +7 more
core   +1 more source

Cost-effectiveness of three echinocandins and fluconazole in the treatment of candidemia and/or invasive candidiasis in nonneutropenic adult patients

ClinicoEconomics and Outcomes Research, 2015
S Grau,1 JC Pozo,2 E Romá,2 M Salavert,3 JA Barrueta,4 C Peral,4 I Rodriguez,5 D Rubio-Rodríguez,6 C Rubio-Terrés6 1Hospital del Mar (IMIM), Barcelona, 2Hospital Universitario Reina Sofía, Córdoba, 3Hospital ...
Grau S, Pozo JC, Romá E, Salavert M, Barrueta JA, Peral C, Rodriguez I, Rubio-Rodríguez D, Rubio-Terrés C   +8 more
doaj  

Safety and efficacy of echinocandin antifungal agents in Candida albicans endophthalmitis

Antimicrobial Agents and Chemotherapy
To evaluate the safety and efficacy of echinocandins (rezafungin, RZF; anidulafungin, AFG) in Candida albicans (C. albicans) endophthalmitis, with a particular focus on the novel drug RZF.
Yue Zhang, Yi Tang, Yanjie Zhou, Hong Wu
doaj   +1 more source

[Anidulafungin].

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2008
Anidulafungin is a new echinocandin antifungal agent recently approved in Spain by the Spanish Drug Agency. As other echinocandins, it inhibits a selective target, 1,3- beta-D-glucan synthesis, a major structural component of the fungal cell wall which is not present in mammalian cells, this avoiding toxicity problems.
M, Gobernado, E, Cantón
openaire   +1 more source

Anidulafungin for Neonatal Hematogenous Candida Meningoencephalitis: Identification of Candidate Regimens for Humans Using a Translational Pharmacological Approach

, 2012
Hematogenous Candida meningoencephalitis (HCME) is a serious infection in premature neonates. Anidulafungin is an echinocandin antifungal agent with potent activity against Candida spp., but its efficacy ...
Peter A. Warn, William W. Hope, Gregson, Lea, Susan Howard, Goodwin, Joanne, Joanne Goodwin, Michael Cohen-Wolkowiez, Cohen-Wolkowiez, Michael, Ruta Petraitiene, Daniel K. Benjamin, Vidmantas Petraitis, Petraitis, Vidmantas, Howard, Susan, Thomas J. Walsh, Warn, Peter A, Timothy W. Felton, Livermore, Joanne, Andrew Sharp, Lea Gregson, Felton, Timothy W; id_orcid, Petraitiene, Ruta, Joanne Livermore, Sharp, Andrew   +22 more
core   +1 more source

Anidulafungin liposome nanoparticles exhibit antifungal activity against planktonic and biofilm Candida albicans

, 2020
Fungal infections can cause significant patient morbidity and mortality. Nanoparticle therapeutics have the potential to improve treatment of these infections.
Luc Langlois, Bailey-Hytholt, Christina M., Langlois, Luc, Felipe de Camargo Ribeiro, Evelyn Luzia de Souza Santos, de Camargo Ribeiro, Felipe [UNESP], Juliana Campos Junqueira, Shukla, Anita, Noel Vera‐González, Christina M. Bailey‐Hytholt, Anita Shukla, Vera-González, Noel, Junqueira, Juliana Campos [UNESP], de Souza Santos, Evelyn Luzia [UNESP]   +13 more
core   +1 more source

Anidulafungin increases the antibacterial activity of tigecycline in polymicrobial Candida albicans/Staphylococcus aureus biofilms on intraperitoneally implanted foreign bodies

, 2018
Objectives: We aimed to establish a novel murine intra-abdominal foreign body infection model to study the activity of anidulafungin and tigecycline against dual species Candida albicans/Staphylococcus aureus biofilms.
Rogiers, Ona, Van Bambeke, Françoise, Soňa Kucharíková, Wafi Siala, Holtappels, Michelle, Siala, Wafi, Lagrou, Katrien, Van Dijck, Patrick, Ona Rogiers, Patrick Van Dijck, Mohamed Lamkanfi, Kucharíková, Soňa, Françoise Van Bambeke, Katrien Lagrou, Michelle Holtappels, Lamkanfi, Mohamed   +15 more
core   +1 more source

Multicenter Analysis of Anidulafungin Use in Invasive Candida Infections

, 2019
Giriş: Tüm dünyada fungal infeksiyonlar önemli bir sorun olup değişen hasta profili ile birlikte sıklığı artmıştır. Özellikle kandida halen en sık karşılaşılan fungal etken olup son yıllarda albikans dışı kandidaların önemi artmıştır.
Kutsoylu, Oya Eren, Pullukçu, Hüsnü, Kutlu, Selda Sayın, Öztürk, Barçın, Kaya, Onur, Yapar, Nur, Taşbakan, Meltem Işıkgöz   +6 more
core   +1 more source

Anidulafungin in the treatment of patients with invasive candidiasis

, 2008
Echinocandins have emerged as important agents for the treatment of invasive candidiasis. Forthcoming guidelines are expected to recommend an echinocandin agent as initial primary therapy in patients who are severely ill and/or have risk factors for ...
Cubillos, G Fernando, Kett, Daniel H
core   +1 more source

Discovery of Small-Molecule PD-L1 Inhibitors via Virtual Screening and Their Immune-Mediated Anti-Tumor Effects

Pharmaceuticals
Background/Objectives: Monoclonal antibodies targeting the PD-1/PD-L1 immune checkpoint have achieved clinical success but face drawbacks such as poor oral bioavailability, limited tumor penetration, and immune-related adverse events.
Chunlai Feng, Yingying Ge, Siqi Wang, Mengru Li, Qiying Chen, Hangyu Dong, Mengjie Rui   +6 more
doaj   +1 more source