Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin [PDF]
We identified a case of breakthrough candidemia in a 25-year-old patient receiving micafungin prophylaxis (50 mg/day). Five Candida glabrata isolates were obtained from blood cultures and were classified as multidrug-resistant isolates, since all of them
Bizerra, Fernando Cesar+6 more
core +2 more sources
Fungal Biomolecules for Food and Pharmaceutical Application
The review summarizes the diverse roles of fungal biomolecules in the food and pharmaceutical industries and highlights their significant contribution to modern medicine and health‐related fields. ABSTRACT Mushrooms have long been an integral part of human culture and health and are valued for their nutritional and therapeutic properties.
Giancarlo Angeles Flores+4 more
wiley +1 more source
Anidulafungin Versus Micafungin in the Treatment of Candidemia in Adult Patients
Echinocandins are recommended for the treatment of invasive candidiasis and candidemia. However, there are few studies comparing anidulafungin and micafungin in terms of efficacy and safety.
J. Suh+5 more
semanticscholar +1 more source
Nakaseomyces glabratus (formerly known as Candida glabrata) is an endogenous opportunistic pathogen that causes various clinical manifestations, ranging from mucocutaneous overgrowth to bloodstream infections. This review aims to summarize the biology, epidemiology and pathology of N.
Carmen Rodríguez‐Cerdeira+8 more
wiley +1 more source
Recent Insights into the Paradoxical Effect of Echinocandins
Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj +1 more source
Epidemiology of invasive candidiasis in a surgical intensive care unit: an observational study [PDF]
Background: Invasive candidiasis (IC) is a frequent and life-threatening infection in critically ill patients. The aim of this study was to evaluate the epidemiology of IC and the antifungal susceptibility of etiological agents in patients admitted to ...
Ana Izquierdo+34 more
core +1 more source
Phenomenon of Dip Effect in Antifungal Susceptibility Testing of Candida tropicalis by using MIC Testing Strips against Echinocandins [PDF]
Minimum Inhibitory Concentration (MIC) of an antifungal is the minimum concentration that completely inhibits the visible growth of fungi under regulated, uniform and consistent in-vitro conditions.
Sujata lall, Vivek Bhat
doaj +1 more source
Efficacy of the Combination of Voriconazole and Caspofungin in Experimental Pulmonary Aspergillosis by Different Aspergillus Species [PDF]
OBJECTIVES: Invasive pulmonary aspergillosis (IPA) caused by Aspergillus fumigatus, Aspergillus flavus, or Aspergillus niger is associated with high mortality. We evaluated the efficacy and compared the therapeutic effect differences of voriconazole (VRC)
Fei Chen+5 more
core +1 more source
Invasive Mould Infections Following Combat‐Related Injuries—A Retrospective Cohort Study
ABSTRACT Background Available data on combat wound‐related invasive mould infections (IMIs) are limited. Objectives We aimed to describe the characteristics and outcomes of IMIs in casualties of a recent conflict. Patients/Methods A retrospective study including hospitalised patients with combat‐related injuries, fulfilling criteria for wound‐related ...
Tomer Hoffman+11 more
wiley +1 more source
Echinocandins are the recommended first-line antifungals for treatment of invasive candidiasis. The increasing number of Candida glabrata strains resistant against echinocandins is an emerging health care concern.
M. Vatanshenassan+6 more
semanticscholar +1 more source