Results 41 to 50 of about 2,230,364 (263)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Kajian Potensi Limbah Pertanian Sebagai Pakan Ternak Ruminansia di Kabupaten Aceh Besar

Jurnal Agripet, 2010
Evaluation of the potency of agricultural by product as ruminant animal feed in aceh besar regency ABSTRACT. A research to evaluate the potency of agricultural by product as animal feed was conducted in Aceh Besar Regency from June to December 2009. The
Samadi Samadi, Yunasri Usman, Mira Delima   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Effect of Tannic Acid on Antioxidant Function, Immunity, and Intestinal Barrier of Broilers Co-Infected with Coccidia and Clostridium perfringens

Animals
The purpose of this study was to determine the efficacy of tannic acid on the antioxidative function, immunity, and intestinal barrier of broilers co-infected with coccidia and Clostridium perfringens (CCP).
Zhengfan Zhang, Pengtao Xu, Chengao Liu, Jing Chen, Bingbing Ren, Encun Du, Shuangshuang Guo, Peng Li, Lanlan Li, Binying Ding   +9 more
doaj   +1 more source

Effect of anaerobic digestate fuel pellet production on Enterobacteriaceae and Salmonella persistence

GCB Bioenergy, 2022
Production of digestate pellets for fuel has been identified as a promising circular economy approach to provide renewable energy and additional income to farms, while at the same time presenting the potential to divert raw digestate from nutrient ...
Ashley Cathcart, Beatrice M. Smyth, Christina Forbes, Gary Lyons, Simon T. Murray, David Rooney, Christopher R. Johnston   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Dietary compounded traditional Chinese medicine residue meal improves laying performance, egg quality, and gut barrier integrity in late-phase laying hens

Poultry Science
This study aimed to investigate the impact of compounded traditional Chinese medicine residue meal (CCMR) on late-phase laying hens, focusing on laying performance, egg quality, albumen gel properties, antioxidant status, immunity, and intestinal barrier
Yujiao Lai, Lina Liu, Zhihao Li, Linlin Li, Rong Wang, Fanbing Zhou, Zhouqingyang Qu, Jing Hu, Shuangshuang Guo, Bingkun Zhang   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source