Results 51 to 60 of about 5,444,667 (291)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Vestibular animal models: contributions to understanding physiology and disease

open access: yesJournal of Neurology, 2016
Our knowledge of the vestibular sensory system, its functional significance for gaze and posture stabilization, and its capability to ensure accurate spatial orientation perception and spatial navigation has greatly benefitted from experimental ...
H. Straka, A. Zwergal, K. Cullen
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Post-Exercise Shifts in the Hemato–Biochemical Profile of Unacclimatized Camels (Camelus dromedarius)

open access: yesAnimals
Exercise-unacclimatized dromedary camels regularly perform strenuous work in desert heat; however, their short-term hematologic and biochemical recovery is not well defined.
Mohammed A. Al-Badwi   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Effect of sweet chestnut extract (Farmatan®) on the digestibility and bioavailability of nitrogen and some minerals in the laboratory rats

open access: yesActa Agriculturae Slovenica, 2016
Study was conducted to investigate the dietary effect of hydrolysable tannin from sweet chestnut on the protein digestibility and bioavailability, dry matter and organic matter apparent digestibility and apparent digestibility and apparent ...
Tatjana PIRMAN, Andrej OREŠNIK
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Effect of vitamin-mineral premix on some relationships between serum parameters in breeding horses

open access: yesActa Agriculturae Slovenica, 2003
Eight Arabian stallions were selected from clinically normal horses. After 10 day adaptation period the animals were divided into two equal groups: control and experimental. All horses were housed individually and allowed to walk on sandy paddock twice a
Mansur S. HAREADY
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Probing subicular inputs to the medial prefrontal cortex

open access: yesiScience, 2021
Summary: The hippocampal formation is anatomically and functionally divided into a dorsal and a ventral part, being involved in processing cognitive tasks and emotional stimuli, respectively.
Sanne Beerens   +3 more
doaj   +1 more source

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