Results 71 to 80 of about 5,444,667 (291)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2013 Objetivou-se, com este trabalho, analisar as respostas fisiológicas de duas raças de caprinos nativos do semiárido brasileiro submetidos a ambiente com temperatura e umidade relativa controladas; utilizaram-se 12 animais machos, 6 Canindés e 6 Moxotós ...
Luiz F. de A. Lucena +4 more
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Ocean warming drives tissue-wide metabolic reprogramming in a fish
iScienceSummary: Ocean warming and marine heatwaves are predicted to have adverse impacts on marine organisms. Yet, knowledge of the molecular mechanisms that underpin successful or failed acclimation to increasing temperatures remains incomplete.
Billy Moore +4 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Guidelines for Animal Exercise and Training Protocols for Cardiovascular Studies.
American Journal of Physiology. Heart and Circulatory Physiology, 2020 Whole body exercise tolerance is the consummate example of integrative physiological function among the metabolic, neuromuscular, cardiovascular and respiratory systems.
D. Poole +8 more
semanticscholar +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Development of Professional Skills through Subject Animal Anatomophysiology
Agrisost, 2019 Context: One of the most important problems of pedagogical work in higher education is the process of professional skills training, which is part of professional education, in which scientific information should be applied in a creative manner to provide
Humberto B. Sóñora Revoredo +4 more
doaj
Role of platelet-derived growth factors in physiology and medicine.
Genes & Development, 2008 Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as prototypes for growth factor and receptor tyrosine kinase function for more than 25 years. Studies of PDGFs and PDGFRs in animal development have revealed roles for PDGFR-
Johanna Andrae, R. Gallini, C. Betsholtz
semanticscholar +1 more source