Anion transport by the cochlear motor protein prestin
Non‐technical summary Cochlear inner hair cells transform acoustic signals into electric signals. Another type of hair cells, outer hair cells, actively amplifies sensory signals and thus contributes to the exquisite sensitivity of the human auditory system.
Michael Schänzler, Christoph Fahlke
semanticscholar +6 more sources
Transport activity of AE3 chloride/bicarbonate anion-exchange proteins and their regulation by intracellular pH. [PDF]
Plasma membrane Cl(-)/HCO(3)(-) anion-exchange (AE) proteins contribute to regulation of intracellular pH (pH(i)). We characterized the transport activity and regulation by pH(i) of full-length AE3 and the cardiac isoform, AE3c, both of which are ...
D. Sterling, J. Casey
semanticscholar +3 more sources
Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei. [PDF]
CLC type anion transport proteins are homo-dimeric or hetero-dimeric with an integrated transport function in each subunit. We have identified and partially characterized three members of this family named TbVCL1, TbVCL2 and TbVCL3 in Trypanosoma brucei.
Steinmann ME+8 more
europepmc +2 more sources
The Human Organic Anion Transport Protein SLC21A6 Is Not Sufficient for Bilirubin Transport [PDF]
A recent study (Cui, Y., Konig, J., Leier, I., Buchholz, U., and Keppler, D. (2001) J. Biol. Chem. 276, 9626-9630) suggests that human OATP2 (SLC21A6), also known as OATP-C and LST1, mediates hepatic bilirubin transport. Because of methodologic concerns, this study was designed to examine this issue using a bilirubin transport assay that was validated ...
Richard B. Kim+3 more
openaire +5 more sources
Biosynthesis of the erythrocyte anion transport protein. [PDF]
The biosynthesis of the erythrocyte anion transport protein (Band III) was studied in erythroid precursor cells obtained from the spleens of anemic mice. Newly synthesized Band III was inserted during or immediately after translation into rough endoplasmic reticulum membranes.
H F Lodish, W A Braell
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Transport activity of chimaeric AE2-AE3 chloride/bicarbonate anion exchange proteins.
Chloride/bicarbonate anion exchangers (AEs), found in the plasma membrane of most mammalian cells, are involved in pH regulation and bicarbonate metabolism.
J. Fujinaga+2 more
semanticscholar +2 more sources
The human erythrocyte anion-transport protein. Partial amino acid sequence, conformation and a possible molecular mechanism for anion exchange. [PDF]
The N-terminal 72 residues of an integral membrane fragment, P5, of the human erythrocyte anion-transport protein, which is known to be directly involved in the anion-exchange process, was shown to have the following amino acid sequence: Met-Val-Pro-Lys ...
C. Brock, M. Tanner, C. Kempf
semanticscholar +2 more sources
Cloning and expression ofSLC10A4, a putative organic anion transport protein
To determine if novel bile acid transporters may be expressed in human tissues.SLC10A1 (NTCP) was used as a probe to search the NCBI database for homology to previously uncharacterized ESTs. The homology search identified an EST (termed SLC10A4) that shares sequence identity with SLC10A1 and SLC10A2 (ASBT).
Patrick L. Splinter+3 more
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The choroid plexus epithelium is the site of the organic anion transport protein in the brain [PDF]
The mRNA for organic anion transport protein (oatp) was previously shown to be present in abundance in liver and kidney, and in small amounts in brain. Data obtained from experiments with reverse transcriptase–PCR techniques and in situ hybridization analysis showed that the oatp mRNA is present within the brain ...
Angeletti, R. H.+5 more
openaire +5 more sources
Transport of organic anions by multidrug resistance-associated protein in the erythrocyte.
The active transport of oxidized glutathione and glutathione S-conjugates has been demonstrated for the first time in erythrocytes and this cell remained the main subject of research on the "glutathione S-conjugate pump" for years. Further studies identifled the "glutathione S-conjugate pump" as multidrug resistance-associated protein (MRP).
Mirosław Soszyński+4 more
openaire +5 more sources