Results 11 to 20 of about 164,824 (310)

Organic Anion Transporting Polypeptide 3A1 (OATP3A1)-Gated Bio-Orthogonal Labeling of Intracellular Proteins

Molecules, 2023
Organic anion transporting polypeptides (OATPs) were found to readily deliver membrane impermeable, tetrazine bearing fluorescent probes into cells. This feature was explored in OATP3A1 conditioned bio-orthogonal labeling schemes of various intracellular
Krisztina Németh, Zsófia László, Adrienn Biró, Ágnes Szatmári, Gergely B. Cserép, György Várady, Éva Bakos, Csilla Özvegy-Laczka, Péter Kele   +8 more
doaj   +1 more source

Novel (sulfated) thyroid hormone transporters in the solute carrier 22 family

European Thyroid Journal, 2023
Objective: Thyroid hormone (TH) transport represents a critical first step in governing intracellular TH regulation. It is still unknown whether the full repertoire of TH transporters has been identified.
Zhongli Chen, Robin P Peeters, Wesley Flach, Linda J de Rooij, Sena Yildiz, Alexander Teumer, Matthias Nauck, Rosalie B T M Sterenborg, Joost H W Rutten, Marco Medici, W Edward Visser, Marcel E Meima   +11 more
doaj   +1 more source

Urinary organic anion transporter protein profiles in AKI [PDF]

Nephrology Dialysis Transplantation, 2011
Organic anion transporters (OATs) are located on either the basolateral or the apical membrane of the proximal tubule cell and mediate the absorption and secretion of various drugs and endogenous metabolites. It has been shown that cellular damage in acute kidney injury (AKI) involves three forms of injury: sublethal damage resulting in loss of cell ...
Margarita, Kunin, Eli J, Holtzman, Semyon, Melnikov, Dganit, Dinour   +3 more
openaire   +2 more sources

Using small molecules to facilitate exchange of bicarbonate and chloride anions across liposomal membranes [PDF]

, 2009
Bicarbonate is involved in a wide range of biological processes, which include respiration, regulation of intracellular pH and fertilization. In this study we use a combination of NMR spectroscopy and ion-selective electrode techniques to show that the ...
A Fürstner, AP Davis, AV Koulov, C Yamamoto, D Stefayne, E Gout, ED Steinle, F Hofmeister, FA Norris, FG Riddell, HG Hempling, HM Florman, J Fujinaga, Jeffery T. Davis, JL Sessler, Jose Carlos Iglesias-Sánchez, JR Casey, JW Bennett, JY Choi, K Chang, K Kavallieratos, K Tanigaki, L You, M Nguyen, MS Melvin, NM Koropatkin, NN Gerber, NR Williamson, OA Okunola, Oluyomi A. Okunola, Philip A. Gale, Pilar Prados, PV Santacroce, RA Gottlieb, Roberto Quesada, S Ohkuma, T Sato, Tomás Torroba, V Rizzo, WN Lipscomb, WW Cleland, X Li   +41 more
core   +1 more source

Engineered Pendrin Protein, an Anion Transporter and Molecular Motor [PDF]

Journal of Biological Chemistry, 2011
Pendrin and prestin both belong to a distinct anion transporter family called solute carrier protein 26A, or SLC26A. Pendrin (SLC26A4) is a chloride-iodide transporter that is found at the luminal membrane of follicular cells in the thyroid gland as well as in the endolymphatic duct and sac of the inner ear, whereas prestin (SLC26A5) is expressed in ...
Jie, Tang, Jason L, Pecka, Xiaodong, Tan, Kirk W, Beisel, David Z Z, He   +4 more
openaire   +2 more sources

Electrophysiological study of Arabidopsis ABCB4 and PIN2 auxin transporters: Evidence of auxin activation and interaction enhancing auxin selectivity

Plant Direct, 2021
Polar auxin transport through plant tissue strictly requires polarly localized PIN proteins and uniformly distributed ABCB proteins. A functional synergy between the two types of membrane protein where their localizations overlap may create the degree of
Stephen D. Deslauriers, Edgar P. Spalding   +1 more
doaj   +1 more source

Single-channel measurements of an N-acetylneuraminic acid-inducible outer membrane channel in Escherichia coli [PDF]

, 2012
NanC is an Escherichia coli outer membrane protein involved in sialic acid (Neu5Ac, i.e., N-acetylneuraminic acid) uptake. Expression of the NanC gene is induced and controlled by Neu5Ac. The transport mechanism of Neu5Ac is not known.
Eisenberg, Bob, Giri, Janhavi, Peneff, Caroline M., Tang, John M., Wirth, Christophe   +4 more
core   +1 more source

Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane

mBio, 2013
Wzx flippases are crucial for bacterial cell surface polysaccharide assembly as they transport undecaprenyl pyrophosphate-linked sugar repeat units from the cytoplasmic to the periplasmic leaflets of the inner membrane (IM) for final assembly.
Salim T. Islam, Paul D. W. Eckford, Michelle L. Jones, Timothy Nugent, Christine E. Bear, Christian Vogel, Joseph S. Lam   +6 more
doaj   +1 more source

Anion transporter: highly cell-type-specific expression of distinct polypeptides and transcripts in erythroid and nonerythroid cells [PDF]

, 1985
Affinity-purified antibodies and cDNA probes specific for the chicken erythrocyte anion transporter (also referred to as band 3) have been used to demonstrate that this protein is expressed in a highly cell- type-specific manner in the avian kidney ...
Cox, John V., Lazarides, Elias, Moon, Randall T.   +2 more
core   +1 more source

Absolute Protein Amounts and Relative Abundance of Volume-regulated Anion Channel (VRAC) LRRC8 Subunits in Cells and Tissues Revealed by Quantitative Immunoblotting [PDF]

, 2019
The volume-regulated anion channel (VRAC) plays an important role in osmotic cell volume regulation. In addition, it is involved in various physiological processes such as insulin secretion, glia-neuron communication and purinergic signaling.
Kopp, Anja, Pervaiz, Sumaira, Stauber, Tobias, von Kleist, Lisa   +3 more
core   +1 more source