Results 21 to 30 of about 373,177 (393)

Organization and Dynamics of the Red Blood Cell Band 3 Anion Exchanger SLC4A1: Insights From Molecular Dynamics Simulations

open access: yesFrontiers in Physiology, 2022
Molecular dynamics (MD) simulations have provided new insights into the organization and dynamics of the red blood cell Band 3 anion exchanger (AE1, SLC4A1).
Antreas C. Kalli   +1 more
doaj   +1 more source

Organic Anion Transporting Polypeptide 3A1 (OATP3A1)-Gated Bio-Orthogonal Labeling of Intracellular Proteins

open access: yesMolecules, 2023
Organic anion transporting polypeptides (OATPs) were found to readily deliver membrane impermeable, tetrazine bearing fluorescent probes into cells. This feature was explored in OATP3A1 conditioned bio-orthogonal labeling schemes of various intracellular
Krisztina Németh   +8 more
doaj   +1 more source

Novel (sulfated) thyroid hormone transporters in the solute carrier 22 family

open access: yesEuropean Thyroid Journal, 2023
Objective: Thyroid hormone (TH) transport represents a critical first step in governing intracellular TH regulation. It is still unknown whether the full repertoire of TH transporters has been identified.
Zhongli Chen   +11 more
doaj   +1 more source

Engineered Pendrin Protein, an Anion Transporter and Molecular Motor [PDF]

open access: yesJournal of Biological Chemistry, 2011
Pendrin and prestin both belong to a distinct anion transporter family called solute carrier protein 26A, or SLC26A. Pendrin (SLC26A4) is a chloride-iodide transporter that is found at the luminal membrane of follicular cells in the thyroid gland as well as in the endolymphatic duct and sac of the inner ear, whereas prestin (SLC26A5) is expressed in ...
Jie Tang   +4 more
openaire   +3 more sources

Urinary organic anion transporter protein profiles in AKI [PDF]

open access: yesNephrology Dialysis Transplantation, 2011
Organic anion transporters (OATs) are located on either the basolateral or the apical membrane of the proximal tubule cell and mediate the absorption and secretion of various drugs and endogenous metabolites. It has been shown that cellular damage in acute kidney injury (AKI) involves three forms of injury: sublethal damage resulting in loss of cell ...
Dganit Dinour   +3 more
openaire   +3 more sources

Thiosquaramides: pH switchable anion transporters [PDF]

open access: yes, 2014
The transport of anions across cellular membranes is an important biological function governed by specialised proteins. In recent years, many small molecules have emerged that mimick the anion transport behaviour of these proteins, but only a few of ...
Busschaert, Nathalie   +11 more
core   +1 more source

Using small molecules to facilitate exchange of bicarbonate and chloride anions across liposomal membranes [PDF]

open access: yes, 2009
Bicarbonate is involved in a wide range of biological processes, which include respiration, regulation of intracellular pH and fertilization. In this study we use a combination of NMR spectroscopy and ion-selective electrode techniques to show that the ...
A Fürstner   +41 more
core   +1 more source

Electrophysiological study of Arabidopsis ABCB4 and PIN2 auxin transporters: Evidence of auxin activation and interaction enhancing auxin selectivity

open access: yesPlant Direct, 2021
Polar auxin transport through plant tissue strictly requires polarly localized PIN proteins and uniformly distributed ABCB proteins. A functional synergy between the two types of membrane protein where their localizations overlap may create the degree of
Stephen D. Deslauriers   +1 more
doaj   +1 more source

Monomeric erythrocyte band 3 protein transports anions. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1991
The anion transport system of the human erythrocyte membrane was reconstituted in egg phosphatidylcholine membranes by using either the unmodified transport protein, band 3, or covalently crosslinked band 3 dimers. Unilamellar vesicles of a diameter of 32 +/- 3 nm were then isolated from the sample by passage through a French press and subsequent gel ...
Sabine Lindenthal, Dieter Schubert
openaire   +3 more sources

Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane

open access: yesmBio, 2013
Wzx flippases are crucial for bacterial cell surface polysaccharide assembly as they transport undecaprenyl pyrophosphate-linked sugar repeat units from the cytoplasmic to the periplasmic leaflets of the inner membrane (IM) for final assembly.
Salim T. Islam   +6 more
doaj   +1 more source

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