Biosynthesis of the erythrocyte anion transport protein.
Journal of Biological Chemistry, 1981 The biosynthesis of the erythrocyte anion transport protein (Band III) was studied in erythroid precursor cells obtained from the spleens of anemic mice. Newly synthesized Band III was inserted during or immediately after translation into rough endoplasmic reticulum membranes.
W A, Braell, H F, Lodish
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Structural basis for the reaction cycle of DASS dicarboxylate transporters
eLife, 2020 Citrate, α-ketoglutarate and succinate are TCA cycle intermediates that also play essential roles in metabolic signaling and cellular regulation. These di- and tricarboxylates are imported into the cell by the divalent anion sodium symporter (DASS ...
David B Sauer +8 more
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A family of fluoride-specific ion channels with dual-topology architecture
eLife, 2013 Fluoride ion, ubiquitous in soil, water, and marine environments, is a chronic threat to microorganisms. Many prokaryotes, archea, unicellular eukaryotes, and plants use a recently discovered family of F− exporter proteins to lower cytoplasmic F− levels ...
Randy B Stockbridge +3 more
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In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein. [PDF]
PLoS ONE, 2018 Methotrexate (MTX) is a widely used chemotherapeutic agent, immune suppressant and antimalarial drug. It is a substrate of several human ABC proteins that confer multidrug resistance to cancer cells and determine compartmentalization of a wide range of ...
Agnes Karasik +2 more
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Structure of the CLC-1 chloride channel from Homo sapiens. [PDF]
, 2018 CLC channels mediate passive Cl- conduction, while CLC transporters mediate active Cl- transport coupled to H+ transport in the opposite direction. The distinction between CLC-0/1/2 channels and CLC transporters seems undetectable by amino acid sequence.
MacKinnon, Roderick, Park, Eunyong
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A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle [PDF]
, 2011 Most dairy cows exhibit different degrees of hypocalcaemia around calving because the gestational Ca requirements shift to the disproportionately high Ca requirements of lactation.
Martin-Tereso Lopez, J. +1 more
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Protein Kinase C Activation Downregulates Human Organic Anion Transporter 1-Mediated Transport through Carrier Internalization [PDF]
Journal of the American Society of Nephrology, 2003 Organic anion transport in intact renal proximal tubule cells in animal model systems is downregulated by treatments that activate protein kinase C (PKC). How this downregulation is achieved is not yet known. Stimulation of PKC with sn-1,2-dioctanoylglycerol resulted in strong inhibition of p-aminohippurate transport mediated by the cloned human ...
Wolff, Natascha A. +6 more
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Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs [PDF]
Proceedings of the National Academy of Sciences, 2000 Two prominent members of the ATP-binding cassette superfamily of transmembrane proteins, multidrug resistance 1 (MDR1) P-glycoprotein and multidrug resistance protein 1 (MRP1), can mediate the cellular extrusion of xenobiotics and (anticancer) drugs from normal and tumor cells.
Wijnholds, J. +11 more
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Molecular cloning and characterization of the chloride channel gene family in trifoliate orange
Biologia Plantarum, 2015 Chloride channels (CLCs) play pivotal roles in plant development and anion transport. However, little research has been conducted about the CLC in fruit-bearing plants.
Q. J. Wei +4 more
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The minimal structure containing the band 3 anion transport site. A 35Cl NMR study [PDF]
, 1985 35Cl NMR, which enables observation of chloride binding to the anion transport site on band 3, is used in the present study to determine the minimal structure containing the intact transport site.
Chan, Sunney I. +2 more
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