Results 141 to 150 of about 34,414 (193)

Clinical and Genetic Characterization of 269 Patients With Suspected Inherited Platelet Disorders: The Padua Monocentric Experience

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 856-865, August 2026.
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari, Daniela Regazzo, Antonella Bertomoro, Anna Cerbo, Alessandro Galbiati, Elisabetta Cosi, Paolo Simioni   +6 more
wiley   +1 more source

ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity. [PDF]

Proc Natl Acad Sci U S A, 2019
Yang R, Walder-Christensen KK, Kim N, Wu D, Lorenzo DN, Badea A, Jiang YH, Yin HH, Wetsel WC, Bennett V.   +9 more
europepmc   +1 more source

14‐3‐3 proteins: Central hubs in plant development and stress adaptation

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 3107-3132, August 2026.
This review highlights recent advances elucidating the important roles of 14‐3‐3 proteins in regulating phytohormone networks, biotic and abiotic stress tolerance, growth‐defense trade‐offs, and evolutionary adaptations. Furthermore, it provides a forward‐looking perspective on 14‐3‐3 biology and the development of climate‐resilient smart crops under ...
Jiale Yuan, Qizhang Wang, Jing Cao, Furong Wang, Hua Zhou, Jigang Li, Fang Lin   +6 more
wiley   +1 more source

New targets and designed inhibitors of ASAP Arf-GAPs derived from structural characterization of the ASAP1/440-kD ankyrin-B interaction. [PDF]

J Biol Chem
Li Y, Zhao Y, He Y, Liu F, Xia L, Liu K, Zhang M, Chen K.   +7 more
europepmc   +1 more source

Complex Contributions of Methylglyoxal to Pain, Axon Degeneration, and Diabetic Peripheral Neuropathy

Journal of Neurochemistry, Volume 170, Issue 8, August 2026.
This work reviews how the metabolic by‐product methylglyoxal may contribute to the development of diabetic peripheral neuropathy (DPN), a common complication of diabetes characterized by nerve damage and chronic pain in the extremities. In diabetes, methylglyoxal levels rise due to increased glucose metabolism and reduced detoxification capacity. While
Gentry Totta‐Griese, Douglas E. Wright
wiley   +1 more source

Ankyrin-B Q1283H Variant Linked to Arrhythmias Via Loss of Local Protein Phosphatase 2A Activity Causes Ryanodine Receptor Hyperphosphorylation. [PDF]

Circulation, 2018
Zhu W, Wang C, Hu J, Wan R, Yu J, Xie J, Ma J, Guo L, Ge J, Qiu Y, Chen L, Liu H, Yan X, Liu X, Ye J, He W, Shen Y, Wang C, Mohler PJ, Hong K.   +19 more
europepmc   +1 more source

Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency. [PDF]

Proc Natl Acad Sci U S A, 2017
Lorenzo DN, Bennett V.
europepmc   +1 more source

Physiological mechanisms and therapeutic targets in chronic cough

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Cough is a vital defensive reflex that safeguards the airways; however, it can become maladaptive and pathological. Chronic cough (>8 weeks in duration) affects up to 10% of the global adult population and is associated with considerable health status impairment. The understanding of cough physiology remains limited.
James C. Brown, Katherine L. Rhatigan, Oliver J. Price, Peter S. P. Cho   +3 more
wiley   +1 more source

Disruption of Ankyrin B and Caveolin-1 Interaction Sites Alters Na⁺,K⁺-ATPase Membrane Diffusion. [PDF]

Biophys J, 2017
Junghans C, Vukojević V, Tavraz NN, Maksimov EG, Zuschratter W, Schmitt FJ, Friedrich T.   +6 more
europepmc   +1 more source

A subtype of idiopathic ventricular fibrillation and its relevance to catheter ablation and genetic variants

HeartRhythm Case Reports, 2017
Takahiko Nishiyama, MD, Yoshiyasu Aizawa, MD, FHRS, Shogo Ito, MD, Yoshinori Katsumata, MD, Takehiro Kimura, MD, FHRS, Seiji Takatsuki, MD, FHRS, FESC   +5 more
doaj   +1 more source