Results 171 to 180 of about 34,414 (193)
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Ankyrin-B structurally defines terminal microdomains of peripheral somatosensory axons

Brain Structure and Function, 2012
Axons are subdivided into functionally organized microdomains, which are required for generation and propagation of action potentials (APs). In the central nervous system (CNS), APs are generated near the soma in the axon initial segment (AIS) and propagated by nodes of Ranvier (noR).
Maren, Engelhardt   +4 more
openaire   +2 more sources

Inhibition of Ankyrin-B Expression Reduces Growth and Invasion of Human Pancreatic Ductal Adenocarcinoma

Pancreatology, 2010
In spite of the increasing knowledge of the molecular pathology of pancreatic ductal adenocarcinoma (PDAC), treatment of this tumor still remains an unresolved problem. Thus, the identification of 'novel' genes involved in pancreatic tumor progression is essential for early diagnosis and new treatment regimens of PDAC.
Ying, Chen   +2 more
openaire   +2 more sources

Mechanistic studies of ankyrin-B/ankyrin-G autoinhibition and regulation

2015
Ankyrins are a family of scaffold proteins, which serves to link great varieties of functional related but structurally diverse integral membrane proteins to the spectrin-based cytoskeletons. In vertebrates, the Ankyrin family consists of three members: ankyrin-R (AnkR), ankyrin-B (AnkB) and ankyrin-G (AnkG), encoded by ANK1, ANK2 and ANK3 ...
openaire   +2 more sources

Analysis of ankyrin-B gene mutations in patients with long QT syndrome.

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008
To identify the ankyrin-B gene mutations that cause long QT syndrome (LQTS) and determine the prevalence of such mutations in Japanese patients with LQTS.We conducted a search for ankyrin-B gene mutation in 78 unrelated patients with LQTS (28 males and 50 females, aged 2 to 89 years).
Xiang, Zhou   +12 more
openaire   +1 more source

Identification of novel intracellular mechanisms in developmental spine pruning through Ankyrin B.

2019
Dendritic spines are the predominant site of glutamatergic inputs throughout the brain. Regulation of spines is therefore critical for refining cortical networks. This research sought to define mechanisms for determining spine fate during developmental synapse remodeling.
openaire   +1 more source

Sequence and Structure-Based Analyses of Human Ankyrin Repeats

Molecules, 2022
Broto Chakrabarty   +2 more
exaly  

The ankyrin repeat: a diversity of interactions on a common structural framework

Trends in Biochemical Sciences, 1999
Stephen Smerdon
exaly  

Hematologically important mutations: Ankyrin variants in hereditary spherocytosis

Blood Cells, Molecules, and Diseases, 2005
Patrick Gallagher
exaly  

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