Results 191 to 200 of about 9,634,082 (235)

The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley   +1 more source

Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Obesity is a global health crisis affecting millions, associated with metabolic disorders such as type 2 diabetes and cardiovascular disease. Calebin‐A, a bioactive compound derived from Curcuma species, has shown promise in managing obesity and its complications.
Ali Mahmoudi, Ali Saeedi‐Boroujeni, Sercan Karav, Prashant Kesharwani, Amirhossein Sahebkar   +4 more
wiley   +1 more source

A subtype of idiopathic ventricular fibrillation and its relevance to catheter ablation and genetic variants

HeartRhythm Case Reports, 2017
Takahiko Nishiyama, MD, Yoshiyasu Aizawa, MD, FHRS, Shogo Ito, MD, Yoshinori Katsumata, MD, Takehiro Kimura, MD, FHRS, Seiji Takatsuki, MD, FHRS, FESC   +5 more
doaj   +1 more source

Elevated local [Ca2+] and CaMKII promote spontaneous Ca2+ release in ankyrin-B-deficient hearts. [PDF]

Cardiovasc Res, 2016
Popescu I, Galice S, Mohler PJ, Despa S.
europepmc   +1 more source

Tissue‐Specific Plasticity of DNA Methylation Across Intertidal Microhabitats in Juvenile Mussels (Mytilus californianus)

Molecular Ecology, Volume 35, Issue 11, June 2026.
ABSTRACT Epigenetic modifications to DNA are proposed to underpin plastic responses to environmental change, and the manner in which DNA methylation contributes to plasticity likely differs among tissues. However, few studies have investigated tissue‐specific DNA methylation responses to ecologically relevant environmental stressors in natural settings.
Qiting Cai, Samuel N. Bogan, Richelle L. Tanner, Joanna L. Kelley, W. Wesley Dowd   +4 more
wiley   +1 more source

ESCRT: A Cellular Nexus of Plant Immunity and Pathogen Counter‐Strategies

Molecular Plant Pathology, Volume 27, Issue 6, June 2026.
The endosomal sorting complex required for transport (ESCRT) plays multifaceted roles in plants' responses to pathogens, including regulation of the localization and fate of immune receptors and other related cellular processes. ABSTRACT The endosomal sorting complex required for transport (ESCRT) machinery consists of multiprotein complexes conserved ...
Willam Kyle Sexton, Shunyuan Xiao
wiley   +1 more source

Towards Mechanism-Based Therapies in Arrhythmogenic Cardiomyopathy

JACC: Basic to Translational Science
Jeffrey E. Saffitz, MD, PhD
doaj   +1 more source

<i>Wolbachia</i> uses ankyrin repeats to target specific fly proteins. [PDF]

mBio
Hamilton W, Hardy E, López-Madrigal S, Phelps M, Martin M, Newton I.   +5 more
europepmc   +1 more source

Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT Syndrome. [PDF]

Circ Cardiovasc Genet, 2017
Swayne LA, Murphy NP, Asuri S, Chen L, Xu X, McIntosh S, Wang C, Lancione PJ, Roberts JD, Kerr C, Sanatani S, Sherwin E, Kline CF, Zhang M, Mohler PJ, Arbour LT.   +15 more
europepmc   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source