Results 11 to 20 of about 34,339 (250)

Ekspresi Annexin A2 pada Kanker Ginekologi [PDF]

Obgynia, 2021
Objective: To determine the relationship between ANXA2 expression and various aspects of gynecological cancer. Method: A structured search for studies involving the relationship of ANXA2 and cervical cancer, endometrial cancer and ovarian cancer using ...
William Alexander Setiawan
doaj   +2 more sources

Annexin A2 is regulated by ovarian cancer-peritoneal cell interactions and promotes metastasis [PDF]

, 2013
Our recent research identified the protein annexin A2 to be regulated by ovarian cancer-peritoneal cell interactions. This study investigated the role of annexin A2 in ovarian cancer metastasis and its potential utility as a novel therapeutic target ...
Elder, A., Hoffmann, P., Lokman, N., Oehler, M., Pyragius, C., Ricciardelli, C., Ween, M.   +6 more
core   +4 more sources

A panel of tumor markers, calreticulin, annexin A2, and annexin A3 in upper tract urothelial carcinoma identified by proteomic and immunological analysis [PDF]

, 2014
BACKGROUND: Upper tract urothelial carcinoma (UTUC) is a tumor with sizable metastases and local recurrence. It has a worse prognosis than bladder cancer. This study was designed to investigate the urinary potential tumor markers of UTUC.
Chih-Ming Lu, Han-Hsiang Huang, Jen-Jie Lin, Jiing-Chuan Chen, Jue-Liang Hsu, Ying-Chin Ko, Yu-Jen Wu, Zhong-Hao Din   +7 more
core   +4 more sources

Bridging of membrane surfaces by annexin A2 [PDF]

Scientific Reports, 2018
AbstractThe protein-mediated formation of membrane contacts is a crucial event in many cellular processes ranging from the establishment of organelle contacts to the docking of vesicles to a target membrane. Annexins are Ca2+ regulated membrane-binding proteins implicated in providing such membrane contacts; however, the molecular basis of membrane ...
David Grill, Anna Lívia Linard Matos, Wilke C. de Vries, Sergej Kudruk, Milena Heflik, Wolfgang Dörner, Henning D. Mootz, Bart Jan Ravoo, Hans‐Joachim Galla, Volker Gerke   +9 more
openalex   +3 more sources

Translational implications of targeting annexin A2: From membrane repair to muscular dystrophy, cardiovascular disease and cancer [PDF]

Clinical and Translational Discovery, 2023
Background Annexin A2 contributes to several key cellular functions and processes, including membrane repair. Effective repair prevents cell death and degeneration, especially in skeletal or cardiac muscle, epithelia, and endothelial cells.
Victor G. Kayejo, Hannah Fellner, Roshan Thapa, Peter A. Keyel   +3 more
doaj   +2 more sources

Annexin A2 Heterotetramer: Structure and Function [PDF]

International Journal of Molecular Sciences, 2013
Annexin A2 is a pleiotropic calcium- and anionic phospholipid-binding protein that exists as a monomer and as a heterotetrameric complex with the plasminogen receptor protein, S100A10. Annexin A2 has been proposed to play a key role in many processes including exocytosis, endocytosis, membrane organization, ion channel conductance, and also to link F ...
Bharadwaj, Alamelu, Bydoun, Moamen, Holloway, Ryan, Waisman, David   +3 more
openaire   +4 more sources

S100A10, annexin A2, and annexin a2 heterotetramer as candidate plasminogen receptors [PDF]

Frontiers in Bioscience, 2005
The defining characteristic of a tumor cell is its ability to escape the constraints imposed by neighboring cells, invade the surrounding tissue and metastasize to distant sites. This invasive property of tumor cells is dependent on activation of proteinases at the cell surface.
Mijung Kwon
openalex   +3 more sources

Plasma and Peritoneal Fluid Annexin A2 Levels in Patients with Endometriosis [PDF]

Journal of Inflammation Research, 2023
Michal Zygarowicz,1,* Joanna Kacperczyk-Bartnik,2,3,* Janusz Sierdzinski,4 Cezary Wojtyla,5,6 Piotr Pierzynski,5,6 Grzegorz Manka,7 Mariusz Kiecka,7 Robert Z Spaczynski,8 Piotr Piekarski,9 Beata Banaszewska,10 Artur Jakimiuk,11,12 Tadeusz Issat ...
Zygarowicz M, Kacperczyk-Bartnik J, Sierdzinski J, Wojtyla C, Pierzynski P, Manka G, Kiecka M, Spaczynski RZ, Piekarski P, Banaszewska B, Jakimiuk A, Issat T, Rokita W, Mlodawski J, Szubert M, Sieroszewski P, Raba G, Szczupak K, Kluz T, Kluza M, Lipa M, Warzecha D, Wielgos M, Koc-Zorawska E, Zorawski M, Laudanski P   +25 more
doaj   +2 more sources

Annexin A2 in Inflammation and Host Defense [PDF]

Cells, 2020
Annexin A2 (AnxA2) is a multifunctional calcium2+ (Ca2+) and phospholipid-binding protein that is expressed in a wide spectrum of cells, including those participating in the inflammatory response.
Valentina Dallacasagrande, Katherine A. Hajjar   +1 more
doaj   +3 more sources

Baicalin target protein, Annexin A2, is a target of new antitumor drugs [PDF]

Scientific Reports
Baicalin is a flavonoid extracted from Scutellaria baicalensis Georgi. As it has significant antitumor and apoptosis-inducing effects, baicalin may be useful as a lead compound in new antitumor drug development. However, as the pharmacological actions of
Yoshio Kusakabe, Kazuya Matsumoto, Takahiro Tsuyuki, Yasuhiro Hayashi, Hideaki Watanabe   +4 more
doaj   +2 more sources