Results 101 to 110 of about 25,326,638 (176)

Anoctamin pharmacology

open access: yes
: TMEM16 proteins, also known as anoctamins, are a family of ten membrane proteins with various tissue expression and subcellular localization. TMEM16A (anoctamin 1) is a plasma membrane protein that acts as a calcium-activated chloride channel.
Galietta, Luis Juan Vicente   +1 more
core   +1 more source

Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages

open access: yes, 2015
Purinergic P2X7 receptors (P2X7R) are fundamental to innate immune response. In macrophages, transient stimulation of P2X7R activates several transport mechanisms and induces the scrambling of phospholipids with subsequent membrane blebbing and apoptosis.
Romao, Ana M.   +6 more
core   +1 more source

Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. [PDF]

open access: yes, 2015
Calcium-activated chloride channels of the anoctamin (alias TMEM16) protein family fulfill critical functions in epithelial fluid transport, smooth muscle contraction and sensory signal processing.
Daniel Parthier   +4 more
core   +1 more source

Rhabdomyolysis as an uncommon manifestation of anoctamin-5 muscular dystrophy [PDF]

open access: yes
Background: Anoctamin-5 (ANO5) muscular dystrophy is a rare neuromuscular disease. Muscular weakness and impaired gait may be evident at the moment of diagnosis, serving as defining characteristics of additional muscular dystrophies.
Marta Rodrigues   +3 more
core   +1 more source

초기 신경발생과정에 관여하는 anoctamin chloride 채널의 역할 [PDF]

open access: yes, 2012
학위논문 (석사)-- 서울대학교 융합과학기술대학원 : 분자의학 및 바이오제약학과, 2012. 8. 오우택.The embryonic neurogenesis which new neurons are generated in the embryonic brain is critical for the development of the central nervous system.
오정은
core  

The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels

open access: yes, 2011
The Ca(2+)-activated Cl(-) channels (CaCCs) are involved in a variety of physiological functions, such as transepithelial anion transport, smooth muscle contraction and olfaction.
Ferrera L.   +11 more
core   +1 more source

Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux

open access: yesCellular Physiology and Biochemistry, 2014
Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco   +10 more
doaj   +1 more source

Control of Lung Myofibroblast Activation by Anoctamine-1 [PDF]

open access: yesC57. EXTRACELLULAR MATRIX AND SUBCELLULAR DYNAMICS IN COMPLEX LUNG DISEASE, 2020
N.O. Dulin   +3 more
openaire   +1 more source

Control of Ion Transport by Tmem16a Expressed in Murine Intestine

open access: yesFrontiers in Physiology, 2019
Cl– secretion by the human and murine intestinal epithelium occurs through the cystic fibrosis transmembrane conductance regulator (cftr). However, the Ca2+ activated Cl– channel Tmem16a was shown to contribute to Cl– secretion, mainly, but not ...
Karl Kunzelmann   +8 more
doaj   +1 more source

The scramblase Anoctamin 9 controls the immune response of lymphocytes

open access: yes
Functional data from submission:"The scramblase Anoctamin 9 controls the immune response of ...
Kunzelmann, Karl
core   +1 more source

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