Results 51 to 60 of about 431 (145)
Andrology, Volume 14, Issue 6, Page 1579-1589, September 2026.ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda +7 more
wiley +1 more source
Metabolic Regulation of Macrophages in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
The Journal of Physiology, Volume 604, Issue 16, Page 6659-6674, 15 August 2026.Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
wiley +1 more source
Cells, 2021 The authors and the Cells Editorial Office would like to add the section “Materials and Methods”, which was missing in the original version [...]
Yves Gouriou +12 more
doaj +1 more source
Optimized Joint Relay and Antenna Selection for Enhanced Full‐Duplex Relay Networks
Engineering Reports, Volume 8, Issue 7, July 2026.This study proposes a joint relay and antenna selection strategy for full‐duplex amplify‐and‐forward relay networks. By adaptively optimizing transmitter–receiver configurations based on channel conditions, the method reduces self‐interference, lowers outage probability, and symbol error rate, and enhances spectral efficiency, offering a scalable ...
Deepika Rani Sona +3 more
wiley +1 more source
, 2021 Bacterial expression systems remain a widely used host for recombinant protein production. However, overexpression of recombinant target proteins in bacterial systems such as Escherichia coli can result in poor solubility and the formation of insoluble ...
Dickson, Alan J; id_orcid +13 more
core +1 more source
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance
Nature Communications, 2017 Adenine nucleotide translocase (ANT) 2 promotes ADP/ATP exchange across the mitochondrial inner membrane. Choet al. show that liver specific Ant2 deletion increases uncoupled respiration and protects mice against fatty liver and obesity-induced insulin ...
Joonseok Cho +19 more
doaj +1 more source
Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development
Plant Biotechnology Journal, Volume 24, Issue 5, Page 2787-2810, May 2026.ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu +11 more
wiley +1 more source
Comparison of Dual-Energy X-ray Absorptiometry and Bioelectrical Impedance Analysis in the Assessment of Body Composition in Women with Anorexia Nervosa upon Admission and Discharge from an Inpatient Specialist Unit [PDF]
, 2021 Assessment of body composition is fundamental in diagnosis and treatment of anorexia nervosa (AN). The gold standard dual-energy X-ray absorptiometry (DXA) is expensive and not universally available.
Reed, KK +20 more
core +1 more source
Mitochondrial PAK6 inhibits prostate cancer cell apoptosis via the PAK6-SIRT4-ANT2 complex
Theranostics, 2020 Rationale: P21-activated kinase 6 (PAK6) is a member of the class II PAKs family, which is a conserved family of serine/threonine kinases. Although the effects of PAK6 on many malignancies, especially in prostate cancer, have been studied for a long time, the role of PAK6 in mitochondria remains unknown.
Li, Tingting +7 more
openaire +2 more sources