Results 71 to 80 of about 431 (145)

Schematic model of the enhancement of Apo2L/TRAIL sensitivity by apigenin.

, 2013
Apigenin binds and inhibits ANT2. Inhibition of ANT2 augments Apo2L/TRAIL sensitivity via upregulation of DR5.
Tomoyuki Taniguchi (337403), Toshiyuki Sakai (309632), Tsuneharu Miki (337405), Yosuke Iizumi (337402), Masakatsu Oishi (337401), Wakana Goi (337404)   +5 more
core   +1 more source

RNA-Seq Analysis of Differential Splice Junction Usage and Intron Retentions by DEXSeq. [PDF]

PLoS ONE, 2015
Alternative splicing is an important biological process in the generation of multiple functional transcripts from the same genomic sequences. Differential analysis of splice junctions (SJs) and intron retentions (IRs) is helpful in the detection of ...
Yafang Li, Xiayu Rao, William W Mattox, Christopher I Amos, Bin Liu   +4 more
doaj   +1 more source

HvTT8 Regulates Proanthocyanidin Accumulation in the Barley Testa Layer by Transcriptionally Activating the Flavonoid Biosynthesis Pathway

Plant Direct, Volume 10, Issue 3, March 2026.
ABSTRACT Barley accumulates proanthocyanidins (PA), a type of flavonoid compound, in the testa layer. The accumulated PA have a detrimental effect on the quality of beer and pearled barley. Therefore, controlling PA accumulation in the testa layer is an important breeding objective in barley. PA accumulation is regulated by a ternary complex consisting
Yuki Nakano, Masaru Nakata, Hiromoto Yamakawa, Takuji Tonooka, Hidekazu Maejima, Takashi Nagamine   +5 more
wiley   +1 more source

Isolation and expression analysis of the HvnAnt2 gene in qingke barley (Hordeum vulgare L. var. nudum Hook. f.) varieties with different grain colours

Czech Journal of Genetics and Plant Breeding
To investigate the role of the HvnAnt2 gene in the formation of different qingke barley grain colours, HvnAnt2 was isolated from the leaves of the White 91-97-3 (white), Blue qingke (blue), Kunlun 17 (black), and Purple qingke (purple).
Hongyan Li, Youhua Yao, Likun An, Xin Li, Yongmei Cui, Yixiong Bai, Xiaohua Yao, Kunlun Wu   +7 more
doaj   +1 more source

Reduced Mitochondrial Adenine Nucleotide Translocase 1 (ANT1) Correlates With Aging‐Associated Airway Remodeling

Aging Cell, Volume 24, Issue 12, December 2025.
Adenine nucleotide translocase 1 (ANT1), a mitochondrial ATP transporter, is decreased in the lung epithelium of aged adults and aged mice correlating to pathogenic airway changes. Loss of ANT1 correlates with increased cellular senescence and changes in COL8A1 in the airway epithelium of the lung.
Roshani Jha, Jian Shi, Maggie J. Sedgwick, Justin Sui, Timothy E. Corcoran, Corrine R. Kliment   +5 more
wiley   +1 more source

다양한 암에서 아데닌 뉴클레오티드 트랜스로케이즈 2 (ANT2) 와 포도당 유사체 (FDG) 축적의 연관성 [PDF]

, 2018
학위논문 (박사)-- 서울대학교 대학원 : 의과대학 의과학과, 2018. 8. 정준기.Introduction: [18F]Fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography (PET) has been widely used to detect cancer.
이철희
core  

Knockdown of ANT2 enhances Apo2L/TRAIL-induced apoptosis by upregulating DR5 at the post-transcriptional level.

, 2013
DU145 cells were transfected with two different ANT2 siRNAs (siANT2 #1 and #2) or a non-targeting siRNA (siCtrl) and were incubated for 48 hr. A, ANT2 mRNA was quantified by real-time RT-PCR and normalized by GAPDH.
Tomoyuki Taniguchi (337403), Toshiyuki Sakai (309632), Tsuneharu Miki (337405), Yosuke Iizumi (337402), Masakatsu Oishi (337401), Wakana Goi (337404)   +5 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

ANT2 inhibition sensitizes in A549 to gefitinib by down-regulating the levels of miR-221/222 from Targeting Adenine Nucleotide Translocase-2 (ANT2) to Overcome Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Non–Small Cell Lung Cancer

, 2016
A549 cells were transfected with ANT2-specific shRNA or sc shRNA. At 24 hours of transfection, the expression levels of miR-221 and miR-222 were measured by qRT-PCR.
Soo Jeong Nam (12357553), Ji-Young Jang (47189), Yoon Kyung Jeon (8605224), Bhumsuk Keam (77141), Tae Min Kim (7945694), Chul Woo Kim (15040407), Yong-goo Kim (15067773)   +6 more
core   +1 more source

Sirt5 preserves mitochondrial homeostasis to improve cardiac function in ischemia-reperfusion injury by inhibiting ANT2 lysine lactylation modification

Cellular and Molecular Life Sciences
Myocardial ischemia-reperfusion (IR) injury, a prevalent heart disease, disrupts mitochondrial homeostasis, affecting heart energy metabolism. The role of mitochondrial protein Sirt5 in protecting the heart from IR injury is explored in mice.
Simeng Li, Siman Shen, Yongfang Hong, Kun Ding, Suyun Chen, Jianning Chen, Changsen Wang, Yaofeng Wen, Guixi Mo, Lili Yu, De-Li Shi, Liangqing Zhang   +11 more
doaj   +1 more source