Results 111 to 120 of about 20,389 (266)
Anthrax lethal toxin exerts potent metabolic inhibition of the cardiovascular system
mBioBacillus anthracis causes anthrax through a combination of bacterial infection and toxemia. As a major virulence factor of B. anthracis, anthrax lethal toxin (LT) is a zinc-dependent metalloproteinase, exerting its cytotoxicity through proteolytic ...
Jie Liu +5 more
doaj +1 more source
Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis. [PDF]
Front Cell Dev Biol, 2023 Huang X +7 more
europepmc +1 more source
Cell Propagation of Cholera Toxin CTA ADP-Ribosylating Factor by Exosome Mediated Transfer [PDF]
, 2018 In this study, we report how the cholera toxin (CT) A subunit (CTA), the enzyme moiety responsible for signaling alteration in host cells, enters the exosomal pathway, secretes extracellularly, transmits itself to a cell population.
Boussadia, Zaira +11 more
core +1 more source
Raxibacumab: potential role in the treatment of inhalational anthrax
Infection and Drug Resistance, 2014 Carlos E KummerfeldtDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, SC, USAAbstract: Anthrax is a highly contagious and potentially fatal human disease caused by Bacillus anthracis, an ...
Kummerfeldt CE
doaj
Anthrax toxins and the host: a story of intimacy
Cellular Microbiology, 2003 Although the dramatic events of the year 2001 have revitalized the interest in anthrax, research on Bacillus anthracis and its major virulence factors is one of the oldest theme in microbiology and started with the early works of Robert Koch and Louis Pasteur. The anthrax toxins are central to anthrax pathogenesis. They were discovered in the mid-1950s
Michèle Mock, Tâm Mignot
openaire +3 more sources
Treatment of ovarian cancer with modified anthrax toxin. [PDF]
Proc Natl Acad Sci U S A, 2022 Aktories K.
europepmc +1 more source
BMC Infectious Diseases, 2018 Background Disease caused by Bacillus anthracis is often accompanied by high mortality primarily due to toxin-mediated injury. In the early disease course, anthrax toxins are secreted; thus, antibiotic use is limited to the early stage.
Qi Tang +7 more
doaj +1 more source
Purification and Properties of In Vitro–produced Anthrax Toxin Components [PDF]
, 1968 Donald C. Fish +3 more
openalex +1 more source
DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin. [PDF]
Sci Rep, 2023 Becker L, Plückthun A.
europepmc +1 more source
Bacterial pore-forming toxins: The (w)hole story? [PDF]
, 2018 .: Pore-forming toxins (PFTs) are the most common class of bacterial protein toxins and constitute important bacterial virulence factors. The mode of action of PFT is starting to be better understood.
Bischofberger, M. +4 more
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