Results 51 to 60 of about 142,050 (194)
Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection. [PDF]
Protective antigen (PA), one of the components of the anthrax toxin, is the major component of human anthrax vaccine (Biothrax). Human anthrax vaccines approved in the United States and Europe consist of an alum-adsorbed or precipitated (respectively ...
Matthew D Reed +8 more
doaj +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source
Membrane translocation by anthrax toxin [PDF]
Much attention has been focused on anthrax toxin recently, both because of its central role in the pathogenesis of Bacillus anthracis and because it has proven to be one of the most tractable toxins for studying how enzymic moieties of intracellularly acting toxins traverse membranes.
openaire +2 more sources
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Human monoclonal antibodies that neutralize anthrax toxin by inhibiting heptamer assembly [PDF]
A panel of human anti-anthrax protective antigen IgG1 monoclonal antibodies were evaluated to determine the mechanism of toxin neutralization. AVP-22G12, AVP-1C6 and AVP-21D9 bound to the protective antigen with picomolar affinities to distinct non ...
Jiang, I. +7 more
core
Toxin neutralizing antibodies represent the major mode of protective immunity against a number of toxin-mediated bacterial diseases, including anthrax; however, the cellular mechanisms that lead to optimal neutralizing antibody responses remain ill ...
Anita Verma +5 more
doaj +1 more source
This study constructed a PiggyBac transposon mediated mutagenesis system which was used to investigate the genomic position effect on heterologous production of physcion in Penicillium ruben. This PB platform enables efficient genetic engineering for secondary metabolite production. ABSTRACT The filamentous fungus Penicillium rubens is well known as an
Meng Wu +5 more
wiley +1 more source
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. [PDF]
The recent use of Bacillus anthracis as a bioweapon has stimulated the search for novel antitoxins and vaccines that act rapidly and with minimal adverse effects. B.
Darly J Manayani +12 more
doaj +1 more source
The Intriguing History of Gloves and Their Application to Surgery
Gloves were first worn to protect against cold and injury. In surgery, their purpose now is to reduce surgical site infection and blood‐borne transmission of disease. Surprisingly, their adoption in surgery as a routine has been remarkably recent and had a bizarre origin.
Spencer W. Beasley
wiley +1 more source

