Results 51 to 60 of about 19,232 (195)
Quantitative Assay for Crude Anthrax Toxins [PDF]
Journal of Bacteriology, 1965 Haines, Bertram W. (U.S. Army Biological Laboratories, Frederick, Md.), Frederick Klein, and Ralph E. Lincoln . Quantitative assay for crude anthrax toxins. J. Bacteriol. 89: 74–83.
B W, HAINES, F, KLEIN, R E, LINCOLN
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Microbiology SpectrumThe Gram-positive bacterium Bacillus anthracis is the causative agent of anthrax and a bioterrorism threat worldwide. As a crucial second messenger in many bacterial species, cyclic di-AMP (c-di-AMP) modulates various key processes for bacterial ...
Jia Hu +3 more
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Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection. [PDF]
PLoS ONE, 2015 Protective antigen (PA), one of the components of the anthrax toxin, is the major component of human anthrax vaccine (Biothrax). Human anthrax vaccines approved in the United States and Europe consist of an alum-adsorbed or precipitated (respectively ...
Matthew D Reed +8 more
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Membrane translocation by anthrax toxin [PDF]
Molecular Aspects of Medicine, 2009 Much attention has been focused on anthrax toxin recently, both because of its central role in the pathogenesis of Bacillus anthracis and because it has proven to be one of the most tractable toxins for studying how enzymic moieties of intracellularly acting toxins traverse membranes.
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Anthrax toxin rafts into cells [PDF]
The Journal of Cell Biology, 2003 Anthrax toxin binds to a plasma membrane receptor and after endocytosis exerts its deadly effects on the cell. Until now, however, the mechanism of initial toxin uptake was unknown. In this issue, Abrami et al. (2003) demonstrate that toxin oligomerization clusters the anthrax receptor into lipid rafts and this complex is internalized via the clathrin ...
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mBio, 2018 Toxin neutralizing antibodies represent the major mode of protective immunity against a number of toxin-mediated bacterial diseases, including anthrax; however, the cellular mechanisms that lead to optimal neutralizing antibody responses remain ill ...
Anita Verma +5 more
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Glyburide inhibits the Cryopyrin/Nalp3 inflammasome [PDF]
, 2009 Inflammasomes activate caspase-1 for processing and secretion of the cytokines interleukin-1 beta (IL-1 beta) and IL-18. Cryopyrin/NALP3/NLRP3 is an essential component of inflammasomes triggered by microbial ligands, danger-associated molecular patterns
Mohamed Lamkanfi +43 more
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A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. [PDF]
PLoS Pathogens, 2007 The recent use of Bacillus anthracis as a bioweapon has stimulated the search for novel antitoxins and vaccines that act rapidly and with minimal adverse effects. B.
Darly J Manayani +12 more
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The Role of Scientific Discovery in the Establishment of the First Biological Weapons Programmes [PDF]
, 2005 YesThis report addresses the scientific and technological discoveries in the biological sciences that enabled the early interest in biological warfare to move from hurling infected corpses into enemy cities in ancient times, through use of small cultures
Davison, N.
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Anthrax Toxin Receptor 2 Determinants that Dictate the pH Threshold of Toxin Pore Formation [PDF]
, 2011 The anthrax toxin receptors, ANTXR1 and ANTXR2, act as molecular clamps to prevent the protective antigen (PA) toxin subunit from forming pores until exposure to low pH.
Collier, R. John +5 more
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