Results 161 to 170 of about 4,586,589 (282)

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Beyond the Cochrane review: Re-evaluating anti-amyloid therapy in Alzheimer's disease. [PDF]

Alzheimers Dement
Bernath MM, Brosch J, Saykin AJ, Wilcock D, Summanwar D, Willis DR.   +5 more
europepmc   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Real-World Patient Eligibility for Alzheimer's Disease Anti-Amyloid Therapy in Seven Swedish Memory Clinics. [PDF]

Eur J Neurol
Rosenberg A, Rennie A, Ekman U, Daniilidou M, Hall A, Matton A, Solomon A, Wahlund LO, Kivipelto M, Westman E.   +9 more
europepmc   +1 more source

Duodenum amyloid deposition

, 2005
Duodenum with amyloid deposition in lamina propria. Amyloid etiology unknown.

core  

Artificial intelligence‐assisted nanozyme design for medical and environmental applications

Journal of Intelligent Medicine, EarlyView.
AI‐assisted nanozyme design integrates cross‐source data and machine learning to enable predictive structure‐activity relationships, accelerating intelligent diagnostics, precision therapeutics, and environmental surveillance. Abstract Nanozymes, a class of nanomaterials with intrinsic enzyme‐like catalytic activities, have emerged as promising ...
Xiaolin Guo, Hao Zhang, Zihan Zhao, Qingshan Liu, Jiayi Liu, Jiang Huang, Changlong Liu, Xiaoyu Mu   +7 more
wiley   +1 more source

Periodontitis and gastric disorders: Systematic review and meta‐analysis of functional dyspepsia and Helicobacter pylori gastritis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood, Jasim Mohammed Abbood, Ekin Yay‐Kus, Iain L. C. Chapple   +3 more
wiley   +1 more source

Before the bolus: why anti-amyloid therapy must become part of every stroke code. [PDF]

Ann Med Surg (Lond)
Khaliq AS, Khan K.
europepmc   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Imaging for anti-amyloid therapy eligibility: Comparing GRE and SWI in detecting microhemorrhages and superficial siderosis. [PDF]

Alzheimers Dement (Amst)
Ford JN, Ferraciolli SF, Chagui OG, Relerford M, Cadavid EC, Dickson J, Vejdani-Jahromi M, DeSalvo MN, Gomez LAR, Yee S, Griffin HR, Kozak B, Rohatgi S, Huang RY, Gomez-Isla T, Romero J.   +15 more
europepmc   +1 more source