Results 171 to 180 of about 4,586,589 (282)

Potential of anti-amyloid therapies for patients with Alzheimer disease in Canada

Canadian Family Physician
Andrew, Frank, Chris, Frank, Frank, Molnar   +2 more
openaire   +2 more sources

Neuroprotective effects of quercetin in animal models of neurodegenerative diseases: A systematic review and meta‐analysis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho, Hendra Mahakam Putra, Cheol Woon Jung, Gyu Hwan Hyun, Hwan‐Hee Jang, In Guk Hwang, Sung Won Kwon   +6 more
wiley   +1 more source

Beyond Amyloid: Systemic and Brain Frailty as Determinants of Response to Anti-Amyloid Therapy in Alzheimer's Disease-A Conceptual Review. [PDF]

Medicina (Kaunas)
Rus Prelog P, Zupan M, Šabović M, Frol S, Kramberger MG.   +4 more
europepmc   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Communication and shared decision-making for anti-amyloid therapy in early Alzheimer's disease: An exploratory qualitative study of real-world audio-recorded clinical encounters. [PDF]

Alzheimers Dement (N Y)
Paladino J, Echols H, Thacker A, Gale SA, Ramirez Gomez L, Weizenbaum E, Pu CT, Ritchie C, Shah SJ, Lindenberger E.   +9 more
europepmc   +1 more source

An anti-amyloid therapy works for Alzheimer's disease: why has it taken so long and what is next? [PDF]

Brain, 2023
Hardy J, Mummery C.
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Diagnostic accuracy of a two-cut-off approach using the FAQ/MMSE ratio and FAQ for clinical preselection of patients for anti-amyloid therapy. [PDF]

J Neurol Neurosurg Psychiatry
Jiménez-Huete A, Rognoni T, Montoya G, Borda MG, Riverol M, Alzheimer’s Disease Neuroimaging Initiative.   +5 more
europepmc   +1 more source

Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke, Julian J. Lum, David R. Goodlett, Helena Pětrošová, Irena Dapic   +4 more
wiley   +1 more source

From Target Engagement to Treatment Governance: The Evolving Role of Amyloid PET in Anti-Amyloid Therapy. [PDF]

Lancet Reg Health Eur
Filippi M, Cecchetti G, Ghirelli A, Spinelli EG, Rugarli G, Pisano S, Samanes Gajate AM, Chiti A, Agosta F.   +8 more
europepmc   +1 more source