Results 21 to 30 of about 584,999 (246)

Recent Advancement in Drug Design and Discovery of Pyrazole Biomolecules as Cancer and Inflammation Therapeutics

Molecules, 2022
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti-inflammatory, anti-microbial, anti-anxiety, anticancer, analgesic ...
Md. Jahangir Alam, Ozair Alam, Mohd. Javed Naim, Farah Nawaz, Ajay Manaithiya, Mohd Imran, Hamdy Khamees Thabet, Sultan Alshehri, Mohammed M. Ghoneim, Prawez Alam, Faiyaz Shakeel   +10 more
doaj   +1 more source

Medication use by early-stage breast cancer survivors: a 1-year longitudinal study. [PDF]

, 2016
PurposeThe aim of this study is to characterize the patterns of medication use by early-stage breast cancer (ESBC) survivors from diagnosis to 1 year post-chemotherapy.MethodsA single-center longitudinal study was conducted with ESBC patients diagnosed ...
Chan, Alexandre, Lee, Chee Ping, Loh, Kep Yong, Ng, Raymond, Ng, Terence   +4 more
core   +1 more source

Concomitant medication use and clinical outcome of repetitive Transcranial Magnetic Stimulation (rTMS) treatment of Major Depressive Disorder. [PDF]

, 2019
BackgroundRepetitive Transcranial Magnetic Stimulation (rTMS) is commonly administered to Major Depressive Disorder (MDD) patients taking psychotropic medications, yet the effects on treatment outcomes remain unknown.
Chawla, Shweta A, Cook, Ian A, Hunter, Aimee M, Krantz, David E, Leuchter, Andrew F, Levitt, Jennifer G, Minzenberg, Michael J, Rotstein, Natalie M   +7 more
core   +1 more source

Evaluation of Depression and Anxiety Disorders and Correlation with the Treatment of Patients with Psoriasis Vulgaris

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2020
Introduction: Psoriasis is a chronic inflammatory multisystemic disease with several comorbidities, namely anxiety and depression disorders. Methods: In this study, the prevalence of these psychiatric entities was investigated by the PHQ-9 and GAD-7 ...
Adriana Kamilly Leitão Pitman Machado, Caio Vinicius Botelho Brito, João Augusto Gomes de Souza Monteiro de Brito, Carla Andrea Avelar Pires, Francisca Regina Oliveira Carneiro   +4 more
doaj   +1 more source

Insights into the neuroprotective properties of Biochanin-A

Archives of Pharmaceutical Sciences Ain Shams University, 2022
The global morbidity and mortality caused by neurological disorders are significant. Neurodegenerative disorders are anticipated to rise as the population ages because they typically manifest in mid-to-late life.
Sarah Hussein, Mai Fathy Tolba, Haidy E Michel, Samar Azab   +3 more
doaj   +1 more source

Comparison of Oral Midazolam and Promethazine with Oral Midazolam alone for Sedating Children during Computed Tomography

Archives of Academic Emergency Medicine, 2018
Introduction: Both midazolam and promethazine are recommended to be used as sedatives in many studies but each have some side effects that limits their use. Combination therapy as an alternative method, may decreases these limitations.
Hassan Barzegari, Behzad Zohrevandi, Kambiz Masoumi, Arash Forouzan, Ali Asgari Darian, Shaqayeq Khosravi   +5 more
doaj   +1 more source

Cannabidiol prescription in clinical practice: an audit on the first 400 patients in New Zealand

BJGP Open, 2020
Background: Cannabidiol (CBD) is the non-euphoriant component of cannabis. In 2017, the New Zealand Misuse of Drugs Regulations (1977) were amended, allowing doctors to prescribe CBD. Therapeutic benefit and tolerability of CBD remains unclear.
Graham Gulbransen, William Xu, Bruce Arroll   +2 more
doaj   +1 more source

Relationship between antibiotic exposure and subsequent mental health disorders in a primary care health system

Brain, Behavior, & Immunity - Health, 2022
Objective: To evaluate the relationship between antibiotic exposure and subsequent psychiatric disorders in a Pediatric primary care setting. Study design: We conducted a retrospective cohort study using electronic clinical record data for patients ages ...
Laura M. Prichett, Robert H. Yolken, Linxuan Wu, Emily G. Severance, Tina Kumra   +4 more
doaj   +1 more source

Comparing the Sedative Effects of Intranasal Dexmedetomidine, Midazolam, and Ketamine in Outpatient Pediatric Surgeries: A Randomized Clinical Trial [PDF]

Iranian Journal of Medical Sciences
Background: The management of preoperative anxiety in pediatric patients, as well as its implications, has remained challenging for anesthesiologists.
Simin Azemati, Maryam Keihani, Mohammad Ali Sahmeddini, Fatemeh Kanaani Nejad, Laleh Dehghanpisheh, Mohammad Bagher Khosravi, Naeimehossadat Asmarian   +6 more
doaj   +1 more source

How and why systemic inflammation worsens quality of life in patients with advanced cancer [PDF]

, 2017
Introduction: The presence of an innate host systemic inflammatory response has been reported to be a negative prognostic factor in a wide group of solid tumour types in both the operable and advanced setting, both local and distant.
Dolan, Ross D., Horgan, Paul G., McMillan, Donald C., McSorley, Stephen T., Roxburgh, Campbell S.D.   +4 more
core   +1 more source