Results 41 to 50 of about 5,298,732 (170)

Antibodies against advanced glycation end-products and malondialdehyde-acetaldehyde adducts identify a new specific subgroup of hitherto patients with seronegative arthritis with a distinct clinical phenotype and an HLA class II association

RMD Open, 2023
Objective In rheumatoid arthritis (RA) around two-thirds of patients are autoantibody positive for rheumatoid factor, anti-citrullinated protein antibodies and/or anti-carbamylated protein antibodies.
Diane van der Woude, Leendert A Trouw, Tom WJ Huizinga, Annette HM van der Helm-van Mil, René EM Toes, Tineke J van Wesemael, Michelle D van den Beukel, Nicole V Borggreven, Anna Titia W Hoogslag   +8 more
doaj   +1 more source

The Clinical and Research Implications of Anti-carbamylated Protein Antibodies [PDF]

The Journal of Rheumatology, 2017
Autoantibodies play a central role in the clinical management of rheumatoid arthritis (RA). They can be used for diagnostic as well as prognostic purposes. For many years, autoantibody testing in RA was limited to rheumatoid factor (RF), but in the late 1990s, Schellekens and colleagues confirmed that autoantibodies reactive to citrullinated peptides ...
openaire   +2 more sources

Anti-carbamylated protein antibodies are associated with early abatacept response in rheumatoid arthritis. Comment on: Anti-carbamylated protein antibodies as a clinical response predictor in rheumatoid arthritis patients treated with abatacept

Clinical and Experimental Rheumatology, 2021
Peer ...
Castellanos-Moreira, R., Gómez, A., Haro Villar, Isabel, Ruiz-Esquide, V., Marsal, V., Sanmartí, Raimon   +5 more
openaire   +3 more sources

Expression of recombinant multi-coloured fluorescent antibodies in gor ^-/trxB^- E. coli cytoplasm [PDF]

, 2011
Background Antibody-fluorophore conjugates are invaluable reagents used in contemporary molecular cell biology for imaging, cell sorting and tracking intracellular events.
Durvasula, Ravi V., Burchell, Joy Marilyn; id_orcid, Kang, Angray S., Anatoliy Markiv, Burchell, J, Durvasula, R.V., Beatson, R., Beatson Richard, Beatson, Richard; id_orcid, Kang Angray S, Markiv, A., Markiv Anatoliy, Kang, A.S., Richard Beatson, Burchell, J., Durvasula Ravi V, Ravi V Durvasula, Burchell, Joy; id_orcid, Durvasula, RV, Markiv, Anatoliy, Burchell Joy, Markiv, A, Angray S Kang, Beatson, Richard, Joy Burchell, Kang, AS, Beatson, R   +26 more
core   +1 more source

Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy

BMC Musculoskeletal Disorders, 2021
Background Blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50–60% of rheumatoid arthritis (RA) patients. However, there are yet no biomarkers to stratify patients for anti-TNF therapy.
Antonio Julià, María López-Lasanta, Francisco Blanco, Antonio Gómez, Isabel Haro, Antonio Juan Mas, Alba Erra, Ma Luz García Vivar, Jordi Monfort, Simón Sánchez-Fernández, Isidoro González, Mercedes Alperi, Raúl Castellanos-Moreira, Antonio Fernández-Nebro, César Díaz-Torné, Núria Palau, Raquel Lastra, Jordi Lladós, Raimon Sanmartí, Sara Marsal   +19 more
doaj   +1 more source

Anti-carbamylated protein and peptide antibodies as potential inflammatory joint biomarkers in the relatives of rheumatoid arthritis patients [PDF]

, 2020
Q4Q3Pacientes con Artritis reumatoideObjective: Antibodies against carbamylated proteins/peptide (CarP) have been associated with severity in rheumatoid arthritis (RA) patients.
Bautista-Molano, Wilson Armando, Romero-Sánchez, Consuelo, Juan‐Manuel Bello‐Gualtero, Bello-Gualtero, Juan-Manuel, Ramos Casallas, Alejandro, Bautista-Molano, Wilson, Chila Moreno, Lorena, Romero Sánchez, Consuelo, Bello Gualtero, Juan Manuel, Ramos-Casallas, Alejandro, Lorena Chila‐Moreno, Rodríguez C., Luz-Stella, Luz‐Stella Rodríguez, Consuelo Romero‐Sánchez, Chila-Moreno, Lorena, Alejandro Ramos‐Casallas, Rodríguez, Luz Stella, Wilson Bautista‐Molano   +17 more
core   +1 more source

Detection and clinical significance of anti-carbamylated protein antibody in serologically negative patients with rheumatoid arthritis [PDF]

Xin yixue, 2022
Objective To probe into the level and clinical significance of anti-carbamylated protein （CarP） antibody in serologically negative patients with rheumatoid arthritis （RA）.
Wu Tao, Chen Chutao, Yang Lijuan, Zou Yaowei, Ma Jianda, Xu Yanhui, Jia Lei, Dai Lie
doaj   +1 more source

Do anti-carbamylated protein antibodies in rheumatoid arthritis reflect local and systemic osteoporosis? A study of osteoprotegrin and receptor activator for nuclear factor kappa B ligand and radiological assessment

Egyptian Rheumatology and Rehabilitation, 2021
Background One of the most important and dangerous complications of rheumatoid arthritis (RA) is bone loss, which manifested by erosions and juxta-articular or systemic bone loss.
Manal Shawky Hussein, Rasha Ahmed Gaber, Hala Mostafa Elsabagh, Elsayed Mohamed Rageh   +3 more
doaj   +1 more source

Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice [PDF]

, 2010
The motor axonal variant of Guillain-Barré syndrome is associated with anti-GD1a immunoglobulin antibodies, which are believed to be the pathogenic factor. In previous studies we have demonstrated the motor terminal to be a vulnerable site.
Halstead, S., Furukawa, K., Humphreys, P.D, Willison, H.J., McGonigal, R., Rowan, E.G., Greenshields, K.N, Rother, R.P   +7 more
core   +2 more sources

Llama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules [PDF]

, 2011
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (
Schepens, B, Temperton, Nigel J., M. Koenders, C. Theo Verrips, Schillemans, J, Ibanez, Lorena Itatı, J. Melero, de Haard, HJ, Verrips, C. Theo, S. Van Gucht, C.T. Verrips, Michael Saunders, Bert Schepens, Temperton, Nigel J, Ibanez, Lorena, Koenders, M, Melero, Jose A., Schepens Bert, de Haard, Hans J, Vanlandschoot, P, Steven Van Gucht, Gonzalez-Pajuelo Maria, Van Gucht, S, Xavier Saelens, Vanlandschoot Peter, Anna Hultberg, B. Schepens, Gonzalez-Pajuelo, Maria, Schillemans Joris, Koenders, Mireille, Nigel J. Temperton, Saunders Michael, Melero José A., de Haard, Hans J., Schillemans, Joris, Ibañez Lorena Itatí, de Haard Hans J., Temperton Nigel J., Ibañez,, Lorena Itatí, H.J. de Haard, Robin A. Weiss, Hultberg, A, Schepens, Bert, C Theo Verrips, N.J. Temperton, Ibanez, LI, Van Gucht, Steven, Verrips, Theo, Maria Gonzalez-Pajuelo, L.I. Ibanez, Rosseels Valérie, José A Melero, Hans J de Haard, Mireille Koenders, Hultberg Anna, Weiss, RA, Saelens Xavier, Saunders, Michael, R.A. Weiss, Weiss Robin A., Saelens, Xavier, Hans J. de Haard, Lorena Itatí Ibañez, A. Hultberg, Gonzalez-Pajuelo, M, Weiss, Robin A., Saelens, X, Joris Schillemans, Verrips, CT, Peter Vanlandschoot, Van Gucht Steven, M. Saunders, Valérie Rosseels, V. Rosseels, Koenders Mireille, Robin A Weiss, P. Vanlandschoot, Rosseels, V, José A. Melero, Hultberg, Anna, M. Gonzalez-Pajuelo, Rosseels, Valerie, J. Schillemans, Ibañez, Lorena Itatí, Melero, Jose Antonio, Vanlandschoot, Peter, Weiss, Robin A, Saunders, M, Nigel J Temperton, X. Saelens, Melero, José A, Verrips C. Theo, Temperton, NJ, Melero, JA, Verrips, C Theo   +94 more
core   +1 more source