Results 31 to 40 of about 5,298,732 (170)

Biomarkers in Rheumatoid Arthritis: From Traditional Serology to Precision Medicine Integration [PDF]

Diagnostics
The biomarker landscape in rheumatoid arthritis (RA) is evolving from reliance on traditional markers toward integrated, multimodal strategies enabling precision medicine approaches. To critically evaluate emerging biomarkers across serological, cellular,
Muhammad Soyfoo, Julie Sarrand
doaj   +2 more sources

Utility of Anti-Carbamylated Antibodies in Early Rheumatoid Arthritis in South Asian Population

Journal of Clinical Rheumatology and Immunology
Background: This study aimed to evaluate the correlation of anti-carbamylated protein (anti-CarP) antibodies with disease activity in Rheumatoid Arthritis (RA) patients, stratified by Rheumatoid Factor (RF) and/or anti-citrullinated peptide antibodies ...
Chandhu A S, Josna Joseph, John Mathew
doaj   +2 more sources

Anti-carbamylated protein antibodies in rheumatoid arthritis patients and their association with rheumatoid factor. [PDF]

Saudi Med J, 2017
To evaluate levels of anti-carbamylated protein (anti-CarP) antibodies in rheumatoid arthritis (RA) patients and to determine their association with serological parameters and disease activity. Methods: A cross-sectional study involving 105 multiethnic RA patients (48 rheumatoid factor [RF]-positive and 57 RF-negative patients) was conducted at ...
Othman MA, Ghazali WSW, Hamid WZWA, Wong KK, Yahya NK.   +4 more
europepmc   +3 more sources

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis. [PDF]

Arthritis Res Ther, 2015
Anti-carbamylated protein (anti-CarP) antibodies have been described in rheumatoid arthritis (RA) and arthralgia patients at risk of developing RA. To what extent these autoantibodies are specific for RA is unknown. Therefore, we investigated the diagnostic performance of the presence of anti-CarP antibodies for RA in a setting of early arthritis.Anti ...
Shi J, van Steenbergen HW, van Nies JA, Levarht EW, Huizinga TW, van der Helm-van Mil AH, Toes RE, Trouw LA.   +7 more
europepmc   +6 more sources

Rheumatoid arthritis and the proinflammatory cytokine IL-17 [PDF]

Folia Medica, 2023
Introduction: Rheumatoid arthritis (RA) is the most common inflammatory joint disease. Various proinflammatory cytokines are involved in the pathogenesis of this chronic disorder.
Pavel Selimov, Rositsa Karalilova, Ljubinka Damjanovska, Ginka Delcheva, Teodora Stankova, Katya Stefanova, Ana Maneva, Teodor Selimov, Anastas Batalov   +8 more
doaj   +3 more sources

A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis

Frontiers in Immunology, 2021
Seropositive rheumatoid arthritis (RA) is characterized by the presence of rheumatoid factor (RF) and anti-citrullinated protein autoantibodies (ACPA) with different fine-specificities.
Caroline Grönwall, Lisa Liljefors, Holger Bang, Aase H. Hensvold, Aase H. Hensvold, Aase H. Hensvold, Monika Hansson, Linda Mathsson-Alm, Linda Mathsson-Alm, Lena Israelsson, Vijay Joshua, Anna Svärd, Anna Svärd, Ragnhild Stålesen, Philip J. Titcombe, Philip J. Titcombe, Johanna Steen, Luca Piccoli, Natalia Sherina, Cyril Clavel, Elisabet Svenungsson, Elisabet Svenungsson, Iva Gunnarsson, Iva Gunnarsson, Saedis Saevarsdottir, Saedis Saevarsdottir, Alf Kastbom, Guy Serre, Lars Alfredsson, Lars Alfredsson, Vivianne Malmström, Johan Rönnelid, Anca I. Catrina, Anca I. Catrina, Anca I. Catrina, Karin Lundberg, Lars Klareskog, Lars Klareskog, Lars Klareskog   +38 more
doaj   +1 more source

The value of anti-CarP and anti-PAD4 as markers of rheumatoid arthritis in ACPA/RF negative rheumatoid arthritis patients

Therapeutic Advances in Musculoskeletal Disease, 2021
Background: Anti-citrullinated protein antibodies (ACPAs) and rheumatoid factor (RF) are key factors in the American College of Rheumatology/European League Against Rheumatism rheumatoid arthritis (RA) classification criteria markers.
Bogdan Kolarz, Marek Ciesla, Ann K. Rosenthal, Magdalena Dryglewska, Maria Majdan   +4 more
doaj   +1 more source

FRI0517 ANTI-CARBAMYLATED PROTEINS ANTIBODIES INDUCE OSTEOCLASTOGENESIS [PDF]

Annals of the Rheumatic Diseases, 2019
Background Post-translational-modifications (PTMs) are implicated in the pathogenesis of autoimmune diseases, leading to the break of self-tolerance, generation of new autoantigens and production of autoantibodies. Anti-citrullinated-proteins antibodies (ACPA) play a key role in the pathogenesis of rheumatoid arthritis (RA) and many evidences showed ...
Laura Massaro, Tania Colasanti, Francesca Spinelli, Fulvia Ceccarelli, Riccardo Mancini, Arbi Pecani, Enrica Cipriano, Carlo Perricone, Francesca Miranda, Simona Truglia, Francesco Natalucci, Martina Leopizzi, Valeria DI Maio, Carlo Della Rocca, Cristiano Alessandri, Guido Valesini, Fabrizio Conti   +16 more
openaire   +1 more source

Anti-carbamylated protein antibodies: are they useful for the diagnosis of rheumatoid arthritis?

Clinical and Experimental Rheumatology, 2021
ACR/EULAR-2010 classification criteria for rheumatoid arthritis (RA) rely heavily on the presence of anti-citrullinated peptide antibody (ACPA). The role of anti-carbamylated protein antibodies (anti-CarP) in this context is uncertain. We aimed to investigate the value of anti-CarP for RA classification in patients with early inflammatory arthritis ...
Ponchel, F, van Delft, MA, Xie, X, Burska, AN, Duquenne, L, Trouw, LA, Emery, P   +6 more
openaire   +3 more sources

Evolution of anti-modified protein antibody responses can be driven by consecutive exposure to different post-translational modifications

Arthritis Research & Therapy, 2021
Background Besides anti-citrullinated protein antibodies (ACPA), rheumatoid arthritis patients (RA) often display autoantibody reactivities against other post-translationally modified (PTM) proteins, more specifically carbamylated and acetylated proteins.
M. Volkov, A. S. B. Kampstra, K. A. van Schie, A. Kawakami, M. Tamai, S. Kawashiri, T. Maeda, T. W. J. Huizinga, R. E. M. Toes, D. van der Woude   +9 more
doaj   +1 more source