Results 11 to 20 of about 5,298,732 (170)

Clinical and etiological meaning of anti-carbamylated protein antibodies in rheumatoid arthritis [PDF]

Immunological Medicine, 2019
Several autoantibodies against proteins with post-translational modifications have been detected in patients with rheumatoid arthritis (RA) and are called anti-modified protein antibodies (AMPAs).
Shuichiro Nakabo
doaj   +4 more sources

Utility of anti-carbamylated protein antibodies in the diagnosis of early rheumatoid arthritis

Indian Journal of Rheumatology, 2019
Background: Anti-carbamylated protein (anti-CarP) antibodies are present in patients with Rheumatoid arthritis (RA) and may present before disease onset.
Ashraf H Mohamed, Asmaa Enein, Noha Abdelsalam, Mona Balata, Sameh Abdellatif, Ehsan Rizk, Ahmed Fathy   +6 more
doaj   +3 more sources

From Rheumatoid Factor to Anti-Citrullinated Protein Antibodies and Anti-Carbamylated Protein Antibodies for Diagnosis and Prognosis Prediction in Patients with Rheumatoid Arthritis. [PDF]

Int J Mol Sci, 2021
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease mainly involving synovial inflammation and articular bone destruction. RA is a heterogeneous disease with diverse clinical presentations, prognoses and therapeutic responses.
Wu CY, Yang HY, Luo SF, Lai JH.
europepmc   +3 more sources

Carbamylated albumin is one of the target antigens of anti-carbamylated protein antibodies. [PDF]

Rheumatology (Oxford), 2017
Anti-carbamylated protein (anti-CarP) antibodies are detected in RA patients. Fetal calf serum is used as an antigen source in anti-CarP ELISA, and the precise target antigens have not been found. We aimed to identify the target antigens of anti-CarP antibodies.Western blotting of anti-CarP antibodies was conducted.
Nakabo S, Hashimoto M, Ito S, Furu M, Ito H, Fujii T, Yoshifuji H, Imura Y, Nakashima R, Murakami K, Kuramoto N, Tanaka M, Satoh J, Ishigami A, Morita S, Mimori T, Ohmura K.   +16 more
europepmc   +6 more sources

Anti-Carbamylated Fibrinogen Antibodies Might Be Associated With a Specific Rheumatoid Phenotype and Include a Subset Recognizing In Vivo Epitopes of Its γ Chain One of Which Is Not Cross Reactive With Anti-Citrullinated Protein Antibodies

Frontiers in Immunology, 2021
To identify the targets recognized by anti-carbamylated protein antibodies (anti-CarP) in patients with early Rheumatoid Arthritis (RA), to study the cross-reactivity between anti-CarP and anti-citrullinated protein antibodies (ACPA) and to evaluate ...
Pauline Brevet, Pauline Brevet, Claire Lattard, Claire Lattard, Clément Guillou, Pascal Rottenberg, Patrice Fardellone, Xavier Le-Loët, Thierry Lequerré, Thierry Lequerré, Pascal Cosette, Olivier Boyer, Olivier Boyer, Manuel Fréret, Manuel Fréret, Olivier Vittecoq, Olivier Vittecoq   +16 more
doaj   +2 more sources

Research progress on anti-carbamylated protein antibodies in connective tissue disease [PDF]

Xin yixue, 2023
Connective tissue disease （CTD） is a group of chronic autoimmune diseases characterized by pathological changes in systemic organs and multisystems. The diagnosis of CTD mainly depends on clinical manifestations and specific autoantibodies.
Dong Rongrong, Yang Qingrui, Ma Zhenzhen
doaj   +2 more sources

Anti-carbamylated Protein Antibodies Are Detectable in Various Connective Tissue Diseases

The Journal of Rheumatology, 2017
Objective.Anti-carbamylated protein (anti-CarP) antibodies are possible diagnostic biomarkers of anticitrullinated protein antibody (ACPA)-negative rheumatoid arthritis (RA). We aimed to elucidate the prevalence of anti-CarP antibodies in non-RA connective tissue diseases (CTD) because CTD are important in the differential diagnosis of ACPA-negative RA.
Shuichiro, Nakabo, Hajime, Yoshifuji, Motomu, Hashimoto, Yoshitaka, Imura, Ran, Nakashima, Kosaku, Murakami, Nobuo, Kuramoto, Shinji, Ito, Junko, Satoh, Masao, Tanaka, Takao, Fujii, Tsuneyo, Mimori, Koichiro, Ohmura   +12 more
openaire   +3 more sources

Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus [PDF]

Arthritis Research & Therapy, 2018
Background The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to identify patients developing the ...
Fulvia Ceccarelli, Carlo Perricone, Tania Colasanti, Laura Massaro, Enrica Cipriano, Monica Pendolino, Francesco Natalucci, Riccardo Mancini, Francesca Romana Spinelli, Guido Valesini, Fabrizio Conti, Cristiano Alessandri   +11 more
doaj   +2 more sources

Effect of Etanercept on Anti-Carbamylated Protein Antibodies in Patients with Rheumatoid Arthritis [PDF]

Journal of Rheumatic Diseases and Treatment, 2015
Rheumatoid Arthritis (RA) is a systemic, chronic inflammatory disease characterized by inflammation of synovial joints and production of autoantibodies such as Rheumatoid Factor and antibodies directed against modified proteins - i.e. anti-citrullinated peptides antibody (ACPA).
SPINELLI, FRANCESCA ROMANA, Pecani, Arbi, CECCARELLI, FULVIA, ALESSANDRI, cristiano, CONTI, FABRIZIO   +4 more
openaire   +3 more sources

Complement Activation by Post-Translationally Modified Proteins: Links to Chronic Inflammation and Autoimmunity. [PDF]

Immunol Rev
ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
van Greevenbroek MMJ, Trouw LA.
europepmc   +2 more sources