PARP Inhibition Attenuates Acute Kidney Allograft Rejection by Suppressing Cell Death Pathways and Activating PI-3K-Akt Cascade. [PDF]
, 2013 BACKGROUND Novel immunosuppressive therapy facilitates long term allograft survival, but acute tubular necrosis and ischemia-reperfusion during transplantation can compromise allograft function.
Degrell, Péter +6 more
core +6 more sources
Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population. [PDF]
, 2017 We aimed to determine whether autoantibodies against apoA-1 (apolipoprotein A-1; anti-apoA-1 IgG) predict incident coronary artery disease (CAD), defined as adjudicated incident myocardial infarction, angina, percutaneous coronary revascularization, or ...
Antiochos, P. +11 more
core +2 more sources
P22 Anti-carbamylated protein antibodies in systemic lupus erythematosus: clinical and serological associations [PDF]
Poster presentations, 2020 Background/Purpose Anti-carbamylated protein antibodies (anti-CarP) have been described not only in Rheumatoid arthritis but in other systemic autoimmune diseases. Recently, they have been reported in different cohorts of Systemic Lupus Erythematosus (SLE) with a prevalence of 9–28%1–4 in patients selected with arthritis/arthralgias.
Micaela Fredi +8 more
openaire +1 more source
Low oxygen tension primes aortic endothelial cells to the reparative effect of tissue-protective cytokines [PDF]
, 2015 Erythropoietin (EPO) has both erythropoietic and tissue-protective properties. The EPO analogues carbamylated EPO (CEPO) and pyroglutamate helix B surface peptide (pHBSP) lack the erythropoietic activity of EPO but retain the tissue-protective properties
A Anagnostou +57 more
core +1 more source
Frontiers in Immunology, 2021 Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation mainly affecting the joints leading to cartilage and bone destruction.
Caterina Bason +10 more
doaj +1 more source
Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production [PDF]
, 2017 BACKGROUND: Rheumatoid arthritis (RA) is an inflammatory debilitating disease that affects the joints in the early and productive phases of an individual’s life.
Ana L. Alemán-Navarro +12 more
core +1 more source
, 2016 Rheumatoid arthritis is a chronic inflammatory joint disease, which can cause cartilage and bone damage as well as disability. Early diagnosis is key to optimal therapeutic success, particularly in patients with well-characterised risk factors for poor ...
Aletaha, Daniel +2 more
core +1 more source
Arthritis autoantibodies in individuals without rheumatoid arthritis:follow-up data from a Dutch population-based cohort (Lifelines) [PDF]
, 2021 Objectives. To assess whether the presence of arthritis autoantibodies alongside IgG ACPA predicts clinically suspect arthralgia in ACPA-positive subjects without RA. Methods.
Arends, Suzanne +10 more
core +1 more source
Clinical and pathophysiologic relevance of autoantibodies in rheumatoid arthritis
Advances in Rheumatology, 2019 Rheumatoid arthritis (RA) is an autoimmune/inflammatory disease affecting 0.5 to 1% of adults worldwide and frequently leads to joint destruction and disability.
Sara de Brito Rocha +2 more
doaj +1 more source
Journal of Translational Autoimmunity, 2020 Rheumatoid Arthritis (RA) is more common and severe in women compared to men. Both women and men with RA express autoantibodies to post-translationally modified antigens, including citrullinated and homocitrullinated proteins or peptides.
Ewa Cairns +5 more
doaj +1 more source