Results 81 to 90 of about 131,343 (218)

Molecular and epidemiological investigations of lung involvement in very early Rheumatoid arthritis [PDF]

open access: yes, 2015
Rheumatoid arthritis (RA) is a systemic inflammatory joint disease with at least two distinct clinical phenotypes defined by the presence or absence of antibodies, i.e. rheumatoid factor (RF) and/or anti-­‐citrullinated protein antibodies (ACPAs).
Reynisdottir, Gudrun Björk
core   +1 more source

AB0512 ANTI-CARBAMYLATED PROTEIN ANTIBODIES IN SYSTEMIC LUPUS ERYTHEMATOSUS: ARE THEY USEFUL? [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2019
Background: Anti-carbamylated protein antibodies (anti-CarP) have been described not only in Rheumatoid arthritis but in other systemic autoimmune diseases. Recently, they have been reported in different cohorts of Systemic Lupus Erythematosus (SLE) with a prevalence of 9-28% (1-4). Anti-CarP have been proposed as a marker of erosive arthitis in SLE(4)
Rajesh Kumar   +5 more
openaire   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa   +7 more
wiley   +1 more source

Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]

open access: yes, 2014
The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander   +4 more
core   +3 more sources

Anti carbamylated protein antibodies as a diagnostic marker in patients with rheumatoid arthritis and its association with disease activity

open access: yesThe Quarterly journal of medicine, 2021
Despite the diagnostic contribution of anti-citrullinated protein( anti-CCP) antibody and rheumatoid factor (RF), approximately one-third of patients with rheumatoid arthritis (RA) remain seronegative .Anti-carbamylated protein (Anti-Carp ...
Magda Medhat Awad El debsy   +3 more
semanticscholar   +1 more source

Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities

open access: yesArthritis &Rheumatology, Volume 77, Issue 12, Page 1626-1634, December 2025.
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley   +1 more source

Pathogenic role of immune cells in rheumatoid arthritis: Implications in clinical treatment and biomarker development [PDF]

open access: yes, 2018
Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, inflammatory disorder that affects synovial joints, both small and large joints, in a symmetric pattern.
Chow, Sook Khuan *   +5 more
core   +1 more source

Identification of Antibodies to Chondrocyte and Synoviocyte Antigens in Equine Osteoarthritis

open access: yesJournal of Orthopaedic Research, Volume 43, Issue 12, Page 2152-2164, December 2025.
ABSTRACT Innate immune responses within the joint are now known to play a key role in osteoarthritis (OA) pathogenesis. However, comparatively little is known regarding the role of adaptive immune responses in OA, and whether they may be important for initiating and sustaining progressive low‐level joint inflammation.
Peter Linde   +7 more
wiley   +1 more source

Improved diagnosis of rheumatoid arthritis using an artificial neural network

open access: yesScientific Reports, 2022
Rheumatoid arthritis (RA) is chronic systemic disease that can cause joint damage, disability and destructive polyarthritis. Current diagnosis of RA is based on a combination of clinical and laboratory features.
Linlu Bai   +5 more
doaj   +1 more source

Added value of multiple autoantibody testing for predicting progression to inflammatory arthritis in at-risk individuals

open access: yesRMD Open, 2022
Background Predicting progression to clinical arthritis in individuals at-risk of developing rheumatoid arthritis is a prerequisite to developing stratification groups for prevention strategies. Selecting accurate predictive criteria is the critical step
Paul Emery   +7 more
doaj   +1 more source

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