Results 1 to 10 of about 11,963 (190)

Anti-Carbamylated Protein (Anti-CarP) Antibodies in Patients Evaluated for Suspected Rheumatoid Arthritis [PDF]

Diagnostics, 2022
(1) Background: Anti-carbamylated protein (CarP) antibodies have been studied as novel markers to aid in the diagnosis and prognosis of rheumatoid arthritis.
Vincent Ricchiuti, Kelly Y. Chun, Jane M. Yang, Mary Ann Aure, Luis Gomez, Gary L. Norman, Michael Mahler   +6 more
doaj   +4 more sources

Association of circulating levels of anti-CarP antibodies with disease activity, disability and radiological damage in rheumatoid arthritis patients: an open-label, observational study [PDF]

Scientific Reports
Autoantibodies directed against carbamylated proteins (anti-CarP) have been recently identified as predictors for RA development. The aim of this study was to determine the positivity of anti-CarP antibodies in a real-life cohort of RA patients and their
Milica Markovic, Corrado Campochiaro, Branislava Glisic, Milan Petronijevic, Gorica Ristic, Ivan Stanojevic, Danilo Vojvodic, Naomi Viapiana, Marco Matucci-Cerinic, Lorenzo Dagna   +9 more
doaj   +3 more sources

Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodies as an example [PDF]

Arthritis Research & Therapy, 2018
Background The presence of autoantibodies is considered an important characteristic of rheumatoid arthritis (RA); therefore, both anticitrullinated protein antibodies (ACPA) and rheumatoid factor (RF) are included in the 2010 classification criteria for ...
Debbie M. Boeters, Leendert A. Trouw, Annette H. M. van der Helm-van Mil, Hanna W. van Steenbergen   +3 more
doaj   +8 more sources

Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus [PDF]

Arthritis Research & Therapy, 2018
Background The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to identify patients developing the ...
Fulvia Ceccarelli, Carlo Perricone, Tania Colasanti, Laura Massaro, Enrica Cipriano, Monica Pendolino, Francesco Natalucci, Riccardo Mancini, Francesca Romana Spinelli, Guido Valesini, Fabrizio Conti, Cristiano Alessandri   +11 more
doaj   +3 more sources

Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients [PDF]

BMC Musculoskeletal Disorders, 2017
Background Rheumatoid arthritis (RA) patients carry a high risk of cardiovascular morbidity and mortality. The excess of cardiovascular disease cannot be entirely explained by traditional risk factors and the immune system contributes to the development ...
Francesca Romana Spinelli, Arbi Pecani, Francesco Ciciarello, Tania Colasanti, Manuela Di Franco, Francesca Miranda, Fabrizio Conti, Guido Valesini, Cristiano Alessandri   +8 more
doaj   +3 more sources

Triple positivity for autoantibodies in patients with rheumatoid arthritis is associated with a severe course of the disease but not with bone turnover markers [PDF]

Rheumatology
Introduction Rheumatoid arthritis (RA) is a prevalent autoimmune disorder characterized by chronic joint inflammation and progressive bone erosion. Traditional autoantibodies, such as anti-citrullinated peptide antibodies (ACPAs) and rheumatoid factor ...
Tomasz Budlewski, Joanna Sarnik, Olga Brzezinska, Anna Lewandowska-Polak, Tomasz Poplawski, Joanna Samanta Makowska   +5 more
doaj   +2 more sources

Self-assembled nanoparticle vaccine comprised of multiple epitopes provides robust protective immunity against reoviruses in fish model [PDF]

Cell Communication and Signaling
Grass carp reovirus type II (GCRV-II) has inflicted substantial economic damage to aquaculture industry due to highly contagious. To combat epidemic GCRV-II, we rational designed and constructed a multi-epitope nanoparticle vaccine (Pep-Fn) that ...
Fei-Fan Xu, Zhao Zhao, Zhu-Yang Deng, Jia-Lun Tang, Bin Zhu   +4 more
doaj   +2 more sources

Animal Models in Rheumatoid Arthritis: Is There a Correlation Between Autoantibodies in Human Pathology and Animal Models? [PDF]

Biology
RA is a chronic autoimmune disease characterized by synovial inflammation and joint damage, driven by autoantibodies such as ACPA, anti-CarP and RF.
Miguel Marco-Bonilla, Maria Fresnadillo, Macarena de la Riva-Bueno, Gabriel Herrero-Beaumont, Raquel Largo, Aránzazu Mediero   +5 more
doaj   +2 more sources

Recurrent Pouchitis Uncovering De Novo Celiac Disease [PDF]

Case Reports in Gastrointestinal Medicine
We present the case of a 39-year-old woman with a history of severe ulcerative colitis (UC) that was refractory to 5-aminosalicylates, corticosteroids, and biologics, and who subsequently underwent total colectomy with ileal pouch–anal anastomosis (IPAA).
Chakib Khoury, Rebal Nahas, Emanuel Youssef Dib, Karam Karam, Elias Fiani   +4 more
doaj   +2 more sources

Rheumatoid arthritis and the proinflammatory cytokine IL-17 [PDF]

Folia Medica, 2023
Introduction: Rheumatoid arthritis (RA) is the most common inflammatory joint disease. Various proinflammatory cytokines are involved in the pathogenesis of this chronic disorder.
Pavel Selimov, Rositsa Karalilova, Ljubinka Damjanovska, Ginka Delcheva, Teodora Stankova, Katya Stefanova, Ana Maneva, Teodor Selimov, Anastas Batalov   +8 more
doaj   +3 more sources