Results 121 to 130 of about 2,492,664 (191)

Construction and characterization of an anti-CD20 mAb nanocomb with exceptionally excellent lymphoma-suppressing activity

open access: yes, 2015
Hua-Fei Li,1–3,* Cong Wu,4,* Ting Chen,5,* Ge Zhang,1 He Zhao,1 Chang-Hong Ke,1 Zheng Xu21International Joint Cancer Institute, Translation Medicine Institute, 2Planning Division, Scientific Research Department, 3Tumor Immunology and Gene Therapy ...
Zhang G   +6 more
core  

Therapeutic Potential of Propolis in Ulcerative Colitis: A Review of Preclinical Evidence

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review compiles preclinical evidence from studies that investigate the therapeutic potential of propolis extracts derived from different botanical origins, as well as their main bioactive constituents, in the context of ulcerative colitis. The observed beneficial effects are primarily attributed to their antioxidant, immunomodulatory, and anti ...
Thayná Fernandes Barros   +4 more
wiley   +1 more source

Implication de la signalisation du BCR dans le ciblage thérapeutique des lymphomes folliculaires [PDF]

open access: yes, 2010
Une des molécules clés des fonctions biologiques du lymphocyte B est le BCR (B Cell Receptor). Les connaissances concernant l'altération du signal BCR et son implication dans l'apparition des lymphopathies B ne cessent de s'élargir.
Kheirallah, Samar
core  

Scalable Arrayed T‐cell CRISPR Screening in Autologous Tumor Co‐cultures to Prioritize Combination Partners for T‐cell Engagers

open access: yesCurrent Protocols, Volume 6, Issue 11, November 2026.
Abstract T‐cell‐engaging therapies (TCE) have shown clinical promise in hematologic malignancies, but the T‐cell‐intrinsic determinants of TCE‐mediated cytotoxicity remain incompletely defined. This is in part because functional studies in patient‐derived primary samples have been technically challenging.
Keenan Ernste   +9 more
wiley   +1 more source

Monoclonal Antibodies for Waldenström Macroglobulinemia

open access: yes, 2018
For the last 2 decades, anti-CD20 monoclonal antibodies have revolutionized the treatment of patients with B-cell lymphomas. These agents have shown efficacy when used as single agents and also have improved response and survival rates when added to ...
Dominguez, A.   +2 more
core   +1 more source

Production and Characterization of New Anti-Human CD20 Monoclonal Antibody

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2015
The B-cell CD20 antigen is one of the most reliable surface targets in immunotherapy of B lymphoma. In this project, we studied the production and characterization of a new monoclonal antibody against chimeric human CD20 extra loops (hCD20 exl).
Mahdi Fasihi-Ramandi   +4 more
doaj  

Efficacy of anti-CD20 monoclonal antibodies (Mabthera) in patients with progressed hairy cell leukemia

open access: yes, 2001
Recently, a chimeric monoclonal antibody (MoAb) directed against the CD20 antigen (rituximab) has been successfully introduced in the treatment of several CD20-positive B-cell neoplasias and particularly of follicular lymphomas.
Marotta, G.   +13 more
core  

Low tumor burden follicular lymphoma: The state of the art

open access: yesHemaSphere, Volume 10, Issue 11, November 2026.
Abstract Follicular lymphoma (FL) is the commonest indolent non‐Hodgkin lymphoma. Most patients present with advanced‐stage and are stratified by the Groupe d'Etude des Lymphomes Folliculaires (GELF) criteria into high or low tumor burden (LTB). Randomized trials in LTB FL demonstrated no overall survival advantage with immediate treatment compared to ...
Greg Hapgood   +3 more
wiley   +1 more source

Expansion Microscopy Reveals the Spatial Association of Therapeutic Antibody–Receptor Complexes With Cholesterol‐Rich Membrane Domains

open access: yesAngewandte Chemie, Volume 138, Issue 42, 12 October 2026.
We report a super‐resolution strategy that maps cholesterol‐rich membrane domains in whole, intact cells with an effective spatial resolution of ∼40 nm by combining expansion microscopy with a perfringolysin O domain 4 probe. This approach enables direct visualization of the spatial association between CD20 and CD38 complexes and cholesterol‐rich ...
Gang Wen   +9 more
wiley   +2 more sources

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