The Pharmacology of the SLC15A4‐TASL Complex, an Emerging Target for the Treatment of Lupus
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT SLC15A4 is a member of the solute carrier superfamily that has been strongly linked to the pathogenesis of the auto‐immune disease SLE. The endo‐lysosomally localized SLC15A4 has traditionally been considered a proton‐dependent histidine and peptide transporter, but has also been shown to facilitate TLR7, 8, and 9 induced IFN‐alpha signaling ...
Alex L. Wilkinson +5 more
wiley +1 more source
Case Report: Successful treatment of severe pneumocystis carinii pneumonia in a case series of primary nephrotic syndrome after receiving anti-CD20 monoclonal antibody therapy. [PDF]
Front Pediatr, 2022 Liu L +8 more
europepmc +1 more source
Chronotherapy in Hematological Malignancies: Evaluating the Rationale and Evidence
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT Hematological malignancies remain one of the leading causes of morbidity and mortality despite advances in targeted therapies, immunotherapy, and stem cell transplantation. Emerging evidence indicates that treatment efficacy and toxicity depend not only on the choice of therapy but also on its timing relative to the patient's internal ...
Andrej Belančić +7 more
wiley +1 more source
Antibody Conjugates via Disulfide Bridging: Towards therapeutic and diagnostic applications [PDF]
, 2015 Antibodies play a prominent role in chemical and biological research and the largest application of chemical bioconjugation reagents is in the production of antibody conjugates.
Hull, EA
core
Prognostic markers in patients with chronic lymphocytic leukaemia on targeted therapy, chemoimmunotherapy with anti-CD20 monoclonal antibody: a systematic review and meta-analysis of prognostic factors. [PDF]
BMC Cancer, 2022 Mkhwanazi ZA +3 more
europepmc +1 more source
VIEW, Volume 7, Issue 4, August 2026.We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
Hemagophagocytic lymphohistiocytosis associated with recurrent Babesiosis with Lyme disease co-infection in an immunocompromised host on anti-CD20 monoclonal antibody therapy: A case report. [PDF]
IDCases, 2022 Zahra A, Marcos LA.
europepmc +1 more source
Clinical and Translational Science, Volume 19, Issue 8, August 2026.A schematic summary of the population pharmacokinetic model of rituximab in treatment‐naïve Chinese DLBCL patients during induction therapy, along with key clinical implications. ABSTRACT This study aimed to establish and validate a population pharmacokinetic model for rituximab during induction therapy in treatment‐naive patients with diffuse large B ...
Wan‐Yi Zhou +5 more
wiley +1 more source