Results 121 to 130 of about 8,957 (228)

A febrile papulovesicular rash in a patient with pyoderma gangrenosum

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 2, Page 237-239, February 2026.
Anika Rajput Khokhar, Charlotte S. Wilm, Katharina Meier, Kamran Ghoreschi, Ulrike Blume‐Peytavi, Farzan Solimani   +5 more
wiley   +1 more source

Sistemik sklerozda ACPA (Anti Citrullinated Protein Antibody)`nın prognostik değeri

, 2020
49
openaire   +1 more source

Immunomodulation of RA Patients’ PBMC with a Multiepitope Peptide Derived from Citrullinated Autoantigens

Mediators of Inflammation, 2017
Citrullinated peptides are used for measuring anticitrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA). Accumulation of citrullinated proteins in the inflamed synovium suggests that they may be good targets for inducing peripheral ...
Smadar Gertel, Gidon Karmon, Sivan Vainer, Ora Shovman, Martin Cornillet, Guy Serre, Yehuda Shoenfeld, Howard Amital   +7 more
doaj   +1 more source

Study of advanced rheumatoid arthritis [PDF]

, 2014
INTRODUCTION: Rheumatic diseases are considered public health problems affecting millions of people worldwide resulting in high and rising health-care costs.
Andrade, Luiz Eduardo Coelho, Carvalho, Carolina Da Silva, Ferreira-strixino, Juliana, Keusseyan, Silene Peres, Martin, Airton Abrahão, Rangel, João Lucas, Raniero, Leandro José   +6 more
core   +2 more sources

Mechanisms of pain in autoimmunity : the role of antibodies [PDF]

, 2016
Chronic pain in autoimmune diseases, like rheumatoid arthritis (RA), is a common and life- changing problem for many patients. Treatment is usually aimed at reducing inflammation and preserving the function of affected tissues.
Wigerblad, Gustaf
core   +1 more source

Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis

Arthritis Research & Therapy, 2019
Background Anti-citrullinated protein antibodies (ACPA) are central to rheumatoid arthritis (RA) pathogenesis and may develop at inflamed mucosa. We investigated whether asthma, a disease of airway mucosal inflammation, was associated with elevated ACPA ...
Alessandra Zaccardelli, Xinyi Liu, Julia A. Ford, Jing Cui, Bing Lu, Su H. Chu, Peter H. Schur, Cameron B. Speyer, Karen H. Costenbader, William H. Robinson, Jeremy Sokolove, Elizabeth W. Karlson, Carlos A. Camargo, Jeffrey A. Sparks   +13 more
doaj   +1 more source

Epidemiological studies in Malaysia and Sweden on associations between smoking, silica exposure and the risk of developing rheumatoid arthritis [PDF]

, 2012
Rheumatoid arthritis (RA) is a chronic, inflammatory disease, frequently associated with joint destruction. Knowledge regarding the aetiology of RA is mainly generated on Caucasian populations.
Yahya, Abqariyah
core   +1 more source

B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation

Annals of the Rheumatic Diseases, 2018
The majority of patients with rheumatoid arthritis (RA) harbours IgG antibodies targeting citrullinated protein antigens (ACPA). Recently, we showed that >90% of ACPA-IgG in serum are glycosylated in the variable domain.1  N -linked glycosylation requires a consensus sequence in the protein backbone (N-X-S/T (asparagine-X-serine/threonine), where X is ...
Vergroesen, Rochelle D.; Slot, Linda M.; Hafkenscheid, Lise; Koning, Marvyn T.; van der Voort, Ellen I. H.; Grooff, Christine A.; Zervakis, George; Veelken, Hendrik; Huizinga, Tom W. J.; Rispens, Theo; Scherer, Hans U.; Toes, Rene E. M.   +12 more
openaire   +5 more sources

The presence of anti-citrullinated protein antibodies (ACPA) does not affect the clinical response to adalimumab in a group of RA patients with the tumor necrosis factor (TNF) α-308 G/G promoter polymorphism

Clinical Rheumatology, 2011
The introduction of antitumor necrosis factor (TNF) agents has improved the outcome for many patients with rheumatoid arthritis (RA). To date, the only replicated genetic predictor of anti-TNF response is the -308 G > A single-nucleotide polymorphism in the TNF promoter region.
Soto Sáez, Lilian, Sabugo Siraqyan, María Francisca, Catalán Martina, Diego, Wurmann Kiblisky, Pamela, Cermenatti, Tomás, Gatica Rossi, Héctor, Aravena, Octavio, Salazar, Lorena, Aguillón Gutiérrez, Juan Carlos, Cuchacovich Turteltaub, Miguel   +9 more
openaire   +6 more sources

Revisiting the Link Between HLA‐DRB1 Alleles and Autoantibodies in Rheumatoid Arthritis: Association of non‐Shared Epitope Alleles *09 and *15 With High Levels of Anti–Citrullinated Peptide/Protein Antibodies

ACR Open Rheumatology
Objective Autoantibodies serve as essential clinical biomarkers and may indicate etiological mechanisms in rheumatic diseases. In light of the increasing knowledge concerning the diversity and biologic implications of anti–citrullinated peptide/protein ...
Denis Lagutkin, Luis Panaifo, Ahmad‐Fauzi Nurul‐Aain, Lena Israelsson, Monika Hansson, Karin Lundberg, Lars Alfredsson, Johan Askling, RACI consortium, Lars Klareskog, Chun‐Lai Too, Leonid Padyukov   +11 more
doaj   +1 more source