Natural Products as Anti-HIV Agents and Role in HIV-Associated Neurocognitive Disorders (HAND): A Brief Overview [PDF]
Frontiers in Microbiology, 2016 As the threat of Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) persists to rise, effective drug treatments are required to treat the infected people.
Kesava Rao Venkata Kurapati +4 more
doaj +5 more sources
Recent Progress in Synthesis, POM Analyses and SAR of Coumarin-Hybrids as Potential Anti-HIV Agents—A Mini Review [PDF]
Pharmaceuticals, 2023 The human immunodeficiency virus (HIV) is the primary cause of acquired immune deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms and procedures have been pursued to synthesise several anti-HIV agents, but due to the ...
Mustapha Suleiman +8 more
doaj +2 more sources
G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents [PDF]
Molecules, 2015 Though a variety of different non-canonical nucleic acids conformations have been recognized, G-quadruplex structures are probably the structural motifs most commonly found within known oligonucleotide-based aptamers.
Domenica Musumeci +2 more
doaj +2 more sources
Computer-aided discovery of anti-HIV agents. [PDF]
Bioorg Med Chem, 2016 A review is provided on efforts in our laboratory over the last decade to discover anti-HIV agents. The work has focused on computer-aided design and synthesis of non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs) with collaborative efforts on biological assaying and protein crystallography.
Jorgensen WL.
europepmc +4 more sources
In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes. [PDF]
PLoS ONE, 2012 Endogenous serine protease inhibitors (serpins) are anti-inflammatory mediators with multiple biologic functions. Several serpins have been reported to modulate HIV pathogenesis, or exhibit potent anti-HIV activity in vitro, but the efficacy of serpins ...
Mohammed Asmal +6 more
doaj +14 more sources
Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility. [PDF]
Bioorg Med Chem Lett, 2013 Non-nucleoside inhibitors of HIV-1 reverse transcriptase are reported that have ca. 100-fold greater solubility than the structurally related drugs etravirine and rilpivirine, while retaining high anti-viral activity.
Bollini M +4 more
europepmc +3 more sources
Severe psoriatic arthritis in an HIV/AIDS patient treated with several TNF blockers switching: a case-based review [PDF]
Infectious Diseases and Tropical Medicine, 2022 OBJECTIVE: This case-based review aims to describe the clinical findings, treatment, and outcome of an HIV/AIDS patient with psoriatic arthritis (PsA) who received four anti-TNF agents and review case reports concerning this rare clinical association ...
J. Carvalho, C. Rodrigues
doaj +1 more source
Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors
Bioinorganic Chemistry and Applications, 2006 HIV/AIDS pandemics is a serious threat to health and development of mankind, and searching for effective anti-HIV agents remains actual. Considerable progress has been made in recent years in the field of drug development against HIV.
I. Kostova +3 more
doaj +2 more sources
A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera. [PDF]
PLoS ONE, 2013 We report on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to ...
Jessica A Pfeilsticker +7 more
doaj +1 more source
Safety of antiretrovirals in pregnacy [PDF]
Vojnosanitetski Pregled, 2011 nema
Dragović Gordana +5 more
doaj +1 more source