G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents [PDF]
Molecules, 2015 Though a variety of different non-canonical nucleic acids conformations have been recognized, G-quadruplex structures are probably the structural motifs most commonly found within known oligonucleotide-based aptamers.
Domenica Musumeci +2 more
doaj +5 more sources
Natural Products as Anti-HIV Agents and Role in HIV-Associated Neurocognitive Disorders (HAND): A Brief Overview [PDF]
Frontiers in Microbiology, 2016 As the threat of Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) persists to rise, effective drug treatments are required to treat the infected people.
Kesava Rao Venkata Kurapati +4 more
doaj +6 more sources
Recent Progress in Synthesis, POM Analyses and SAR of Coumarin-Hybrids as Potential Anti-HIV Agents—A Mini Review [PDF]
Pharmaceuticals, 2023 The human immunodeficiency virus (HIV) is the primary cause of acquired immune deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms and procedures have been pursued to synthesise several anti-HIV agents, but due to the ...
Mustapha Suleiman +8 more
doaj +3 more sources
Computer-aided discovery of anti-HIV agents. [PDF]
Bioorg Med Chem, 2016 A review is provided on efforts in our laboratory over the last decade to discover anti-HIV agents. The work has focused on computer-aided design and synthesis of non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs) with collaborative efforts on biological assaying and protein crystallography.
Jorgensen WL.
europepmc +5 more sources
Potential Anti-HIV Agents from Marine Resources: An Overview
Marine Drugs, 2010 Human immunodeficiency virus (HIV) infection causes acquired immune deficiency syndrome (AIDS) and is a global public health issue. Anti-HIV therapy involving chemical drugs has improved the life quality of HIV/AIDS patients.
Thanh-Sang Vo, Se-Kwon Kim
doaj +2 more sources
Cyclotides as natural anti‐HIV agents [PDF]
Peptide Science, 2008 AbstractCyclotides are disulfide rich macrocyclic plant peptides that are defined by their unique topology in which a head‐to‐tail cyclized backbone is knotted by the interlocking arrangement of three disulfide bonds. This cyclic cystine knot motif gives the cyclotides exceptional resistance to thermal, chemical, or enzymatic degradation.
Ireland, David C. +4 more
openaire +4 more sources
Discovery of N-arylsulfonyl-3-acylindole benzoyl hydrazone derivatives as anti-HIV-1 agents [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2019 The discovery and development of novel inhibitors with activity against variants of human immunodeficiency virus type 1 (HIV-1) is pivotal for overcoming treatment failure.
Zhiping Che +4 more
doaj +2 more sources
Parthenium hysterophorus: a probable source of anticancer, antioxidant and anti-HIV agents. [PDF]
Biomed Res Int, 2013 The present work reports the anticancer, antioxidant, lipo-protective, and anti-HIV activities of phytoconstituents present in P. hysterophorus leaf. Dried leaf samples were sequentially extracted with nonpolar and polar solvents. Ethanol fraction showed
Kumar S +3 more
europepmc +2 more sources
Discovery of an L-like Configuration for 3'-Fluoro-5'-norcarbonucleoside Phosphonates as Potent Anti-HIV Agents. [PDF]
ChemMedChem, 2022 Geant PY +4 more
europepmc +3 more sources