Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7. [PDF]
For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently needed.
Yaoqing Chen+18 more
doaj +5 more sources
Targeting the PI3K/Akt cell survival pathway to induce cell death of HIV-1 infected macrophages with alkylphospholipid compounds. [PDF]
HIV-1 infected macrophages and microglia are long-lived viral reservoirs persistently producing viral progenies. HIV-1 infection extends the life span of macrophages by promoting the stress-induced activation of the PI3K/Akt cell survival pathway ...
Amanda Lucas+5 more
doaj +5 more sources
Role of darunavir in the management of HIV infection [PDF]
R Monica Lascar, Paul BennThe Mortimer Market Centre, Camden PCT, London WC1E 6JBAbstract: There is an ongoing need for potent antiretroviral therapies to deal with the increasing pool of treatment-experienced patients with multiple drug resistance.
R Monica Lascar, Paul Benn
doaj +3 more sources
Model and experiences of initiating collaboration with traditional healers in validation of ethnomedicines for HIV/AIDS in Namibia [PDF]
Many people with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) in Namibia have access to antiretroviral drugs but some still use traditional medicines to treat opportunistic infections and offset side-effects from ...
Chinsembu Kazhila C
doaj +5 more sources
Anti-latency agents to purge HIV reservoirs [PDF]
Moreno Santiago
doaj +4 more sources
Raltegravir: first in class HIV integrase inhibitor [PDF]
Zelalem Temesgen1, Dawd S Siraj21Mayo Clinic, Rochester, MN, USA; 2East Carolina University Greenville, NC, USAAbstract: On October 16, 2007, the US Food and Drug Administration (FDA) approved raltegravir for treatment of human immunodeficiency virus ...
Zelalem Temesgen, Dawd S Siraj
doaj +3 more sources
Bird's eye view of natural products for the development of new anti-HIV agents: Understanding from a therapeutic viewpoint. [PDF]
Al Amin M+12 more
europepmc +2 more sources
Improving of Robotic Virtual Agent's errors that are accepted by reaction and human's preference [PDF]
One way to improve the relationship between humans and anthropomorphic agents is to have humans empathize with the agents. In this study, we focused on a task between an agent and a human in which the agent makes a mistake. To investigate significant factors for designing a robotic agent that can promote humans empathy, we experimentally examined the ...
arxiv +1 more source
Cyclotides as natural anti‐HIV agents [PDF]
AbstractCyclotides are disulfide rich macrocyclic plant peptides that are defined by their unique topology in which a head‐to‐tail cyclized backbone is knotted by the interlocking arrangement of three disulfide bonds. This cyclic cystine knot motif gives the cyclotides exceptional resistance to thermal, chemical, or enzymatic degradation.
Ireland, David C.+4 more
openaire +4 more sources
Severe psoriatic arthritis in an HIV/AIDS patient treated with several TNF blockers switching: a case-based review [PDF]
OBJECTIVE: This case-based review aims to describe the clinical findings, treatment, and outcome of an HIV/AIDS patient with psoriatic arthritis (PsA) who received four anti-TNF agents and review case reports concerning this rare clinical association ...
J. Carvalho, C. Rodrigues
doaj +1 more source