Results 11 to 20 of about 492,595 (235)

Synthesis, Characterisation, Biological Evaluation and In Silico Studies of Quinoline-1,2,3-Triazole-Anilines as Potential Antitubercular and Anti-HIV Agents. [PDF]

Molecules
Magwaza SS, Naidu D, Oyeneyin OE, Senzani S, Mkhwanazi NP, Tukulula M.   +5 more
europepmc   +3 more sources

2-Aminothiazolones as anti-HIV agents that act as gp120-CD4 inhibitors. [PDF]

Antimicrob Agents Chemother, 2014
Tiberi M, Tintori C, Ceresola ER, Fazi R, Zamperini C, Calandro P, Franchi L, Selvaraj M, Botta L, Sampaolo M, Saita D, Ferrarese R, Clementi M, Canducci F, Botta M.   +14 more
europepmc   +2 more sources

Bird's eye view of natural products for the development of new anti-HIV agents: Understanding from a therapeutic viewpoint. [PDF]

Animal Model Exp Med
Al Amin M, Nafady MH, Zehravi M, Sweilam SH, Kumar KP, Akiful Haque M, Unnisa A, Singh LP, Sayeed M, Alshehri MA, Ahmad I, Emran TB, Uddin MZ.   +12 more
europepmc   +2 more sources

Combining an OSMAC approach and untargeted metabolomics to profile compounds exhibiting anti-HIV-1 activities in an endophytic fungus, Penicillium Rubens P03MB2 [PDF]

Scientific Reports
The persistent burden of HIV-1 in Sub-Saharan Africa underscores the need for innovative treatments, as current antiretroviral therapies cannot eliminate latent proviral reservoirs and face challenges from multidrug-resistant strains.
Neo Moloi, Mothusi C. Khumalo, Wonder P. Nxumalo, Sphamandla E. Mtambo, Nompumelelo P. Mkhwanazi, Sizwe I. Ndlovu   +5 more
doaj   +2 more sources

Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility. [PDF]

Bioorg Med Chem Lett, 2013
Bollini M, Cisneros JA, Spasov KA, Anderson KS, Jorgensen WL.   +4 more
europepmc   +3 more sources

Efficient Discovery of Potent Anti-HIV Agents Targeting the Tyr181Cys Variant of HIV Reverse Transcriptase [PDF]

Journal of the American Chemical Society, 2011
William L. Jorgensen, Mariela Bollini, Vinay V. Thakur, Robert A. Domaoal, Krasimir A. Spasov, Karen S. Anderson   +5 more
openalex   +2 more sources

Severe psoriatic arthritis in an HIV/AIDS patient treated with several TNF blockers switching: a case-based review [PDF]

Infectious Diseases and Tropical Medicine, 2022
OBJECTIVE: This case-based review aims to describe the clinical findings, treatment, and outcome of an HIV/AIDS patient with psoriatic arthritis (PsA) who received four anti-TNF agents and review case reports concerning this rare clinical association ...
J. Carvalho, C. Rodrigues
doaj   +1 more source

Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors

Bioinorganic Chemistry and Applications, 2006
HIV/AIDS pandemics is a serious threat to health and development of mankind, and searching for effective anti-HIV agents remains actual. Considerable progress has been made in recent years in the field of drug development against HIV.
I. Kostova, S. Raleva, P. Genova, R. Argirova   +3 more
doaj   +2 more sources

Anti-HIV agents inspired by antibodies [PDF]

Nature Chemical Biology, 2020
Emergence of drug resistance limits the efficacy of HIV drugs, which currently requires life-long administration. In vitro high-throughput screening for competition with a broadly neutralizing antibody of HIV identified a small molecule that extends the strategies for targeting HIV.
Shan Su, Shibo Jiang, Shibo Jiang
openaire   +2 more sources

A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera. [PDF]

PLoS ONE, 2013
We report on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to ...
Jessica A Pfeilsticker, Aiko Umeda, Blake Farrow, Connie L Hsueh, Kaycie M Deyle, Jocelyn T Kim, Bert T Lai, James R Heath   +7 more
doaj   +1 more source