In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes. [PDF]
PLoS ONE, 2012 Endogenous serine protease inhibitors (serpins) are anti-inflammatory mediators with multiple biologic functions. Several serpins have been reported to modulate HIV pathogenesis, or exhibit potent anti-HIV activity in vitro, but the efficacy of serpins ...
Mohammed Asmal +6 more
doaj +15 more sources
Anti-latency agents to purge HIV reservoirs [PDF]
Retrovirology, 2012 Moreno Santiago
doaj +2 more sources
Mangiferin, an Anti-HIV-1 Agent Targeting Protease and Effective against Resistant Strains [PDF]
Molecules, 2011 The anti-HIV-1 activity of mangiferin was evaluated. Mangiferin can inhibit HIV-1ⅢB induced syncytium formation at non-cytotoxic concentrations, with a 50% effective concentration (EC50) at 16.90 μM and a therapeutic index (TI) above 140. Mangiferin also
Rui-Rui Wang +6 more
doaj +2 more sources
Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents.
Journal of Medicinal Chemistry, 2006 Donglei Yu +6 more
semanticscholar +2 more sources
Journal of the American Chemical Society, 2011 W. L. Jorgensen +5 more
semanticscholar +3 more sources
Severe psoriatic arthritis in an HIV/AIDS patient treated with several TNF blockers switching: a case-based review [PDF]
Infectious Diseases and Tropical Medicine, 2022 OBJECTIVE: This case-based review aims to describe the clinical findings, treatment, and outcome of an HIV/AIDS patient with psoriatic arthritis (PsA) who received four anti-TNF agents and review case reports concerning this rare clinical association ...
J. Carvalho, C. Rodrigues
doaj +1 more source
Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors
Bioinorganic Chemistry and Applications, 2006 HIV/AIDS pandemics is a serious threat to health and development of mankind, and searching for effective anti-HIV agents remains actual. Considerable progress has been made in recent years in the field of drug development against HIV.
I. Kostova +3 more
doaj +2 more sources
Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility. [PDF]
Bioorg Med Chem Lett, 2013 Non-nucleoside inhibitors of HIV-1 reverse transcriptase are reported that have ca. 100-fold greater solubility than the structurally related drugs etravirine and rilpivirine, while retaining high anti-viral activity.
Bollini M +4 more
europepmc +3 more sources
A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera. [PDF]
PLoS ONE, 2013 We report on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to ...
Jessica A Pfeilsticker +7 more
doaj +1 more source
Safety of antiretrovirals in pregnacy [PDF]
Vojnosanitetski Pregled, 2011 nema
Dragović Gordana +5 more
doaj +1 more source