Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang+8 more
wiley +1 more source
Novel 2-(Diphenylmethylidene) Malonic Acid Derivatives as Anti-HIV Agents: Molecular Modeling, Synthesis and Biological Evaluation. [PDF]
Lotfaliei M+6 more
europepmc +1 more source
The chemical composition and the in vitro synergistic antimicrobial effects of four Satureja essential oils were investigated. Essential oils from Satureja montana and S. hortensis displayed strong antimicrobial effects, whereas S. calamintha and S. alpina exhibited relatively weaker antimicrobial activity.
Imane Abbad+3 more
wiley +1 more source
Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex. [PDF]
Ryazantsev DY+13 more
europepmc +1 more source
Promising Prodiginins Biological Activities
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto+6 more
wiley +1 more source
Synthesis, Biological Evaluation, and Molecular Modeling Studies of New 8-methyl-4-oxo-1,4-dihydroquinoline-3-carbohydrazides as Potential Anti-HIV Agents. [PDF]
Alemi M+4 more
europepmc +1 more source
Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features
ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad+5 more
wiley +1 more source
METHODS FOR USING GOLD (III) COMPLEXES AS ANTI-TUMOR AND ANTI-HIV AGENTS [PDF]
Disclosed is the use of gold (III) complexes of porphyrins, Schiff-bases, bis(pyridyl)carboxamides and bis(pyridyl)sulfonamides as anti-tumor and anti-HIV agents ...
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Cannabinoids From Trema micranthum (L.) Blume (Cannabaceae): A Cannabinoid Profiling System
ABSTRACT Trema micranthum (L.) Blume is a species from the Cannabaceae botanical family, present all over the tropics. A recent study conducted by our group identified the presence of cannabidiol (CBD), Δ9‐tetrahydrocannabinol, cannabidiolic acid, and tetrahydrocannabinolic acid‐A in T. micranthum extracts.
Yasmin Cunha‐Silva+7 more
wiley +1 more source
Design, Synthesis, Docking Study and Biological Evaluation of 4-Hydroxy-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide Derivatives as Anti-HIV Agents. [PDF]
Imani A+4 more
europepmc +1 more source