Results 61 to 70 of about 1,938,563 (139)

The Role of Non-Human Sialic Acid Neu5Gc-Containing Glycoconjugates in Human Tumors: A Review of Clinical and Experimental Evidence [PDF]

Biomolecules
Rances Blanco
exaly   +2 more sources

Xenotransplantation of the Porcine Lung—From Immunological Barriers to Emerging Experimental Strategies

Xenotransplantation, Volume 33, Issue 5, September/October 2026.
ABSTRACT Lung transplantation is the only long‐lasting life‐saving treatment for patients with end‐stage pulmonary disease, but the ever‐growing shortage of suitable donor organs leads to high mortality rates of the afflicted patients. Xenotransplantation, the transplantation of organs across species, has emerged as a promising alternative. This review
Nathalie Roters, Niveditha Varma, Robert Ramm, Heiner Niemann, Patrick Zardo, Arjang Ruhparwar, Tobias Goecke   +6 more
wiley   +1 more source

LC–MS Analysis of Polyclonal Human Anti-Neu5Gc Xeno-Autoantibodies Immunoglobulin G Subclass and Partial Sequence Using Multistep Intravenous Immunoglobulin Affinity Purification and Multienzymatic Digestion [PDF]

Analytical Chemistry, 2012
Human polyclonal IgG antibodies directly against the nonhuman sialic acid N-glycolylneuraminic acid (Neu5Gc) are potential biomarkers and mechanistic contributors to cancer and other diseases associated with chronic inflammation. Using a sialoglycan microarray, we screened the binding pattern of such antibodies (anti-Neu5Gc IgG) in several samples of ...
Qiaozhen, Lu, Vered, Padler-Karavani, Hai, Yu, Xi, Chen, Shiaw-Lin, Wu, Ajit, Varki, William S, Hancock   +6 more
openaire   +2 more sources

Generation of recombinant anti-N-glycolylneuraminic acid (Neu5Gc) scFv and its applications for detection and quantitation of Neu5Gc

, 2016
Sialic acids are a family of 9 carbon α-keto acid monosaccharides. Owing to their terminal position on glycans, sialic acids are involved in cell adhesion and recognition events, host pathogen interactions, immune regulation and in disease processes such
Sharma, Rajesh Kumar
core   +1 more source

Maternal and infant gut microbiome

iMeta, Volume 5, Issue 4, August 2026.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Anti-Neu5Gc Antibody Kit Protocol - Western Blot v3 [PDF]

, 2019
The Anti-Neu5Gc Antibody Kit contains the essential monospecific polyclonal chicken IgY antibody, along with a negative control primary antibody to detect the presence of Neu5Gc on glycoconjugates by Western blot (WB). Samples to be evaluated are first subjected to SDS-PAGE, followed by transfer to a nitrocellulose or polyvinylidenedifluoride (PVDF ...
openaire   +1 more source

Reduced Complement and Granulocyte Activation by α‐Gal Knockout Porcine Pericardium for Bioprosthetic Heart Valves: A Pilot Hemocompatibility Study

Journal of Biomedical Materials Research Part A, Volume 114, Issue 7, July 2026.
Genetically modified, α‐Gal‐depleted porcine pericardium and wild type tissues are investigated for hemocompatibility and material properties such as mechanobiology and ECM profile to carve out the suitability of the gene‐modified tissue as material for biological heart valve prostheses. ABSTRACT Xenogeneic pericardium is the main source for biological
Claudia Dittfeld, Elisabeth Kemter, Barbara Kessler, Eckhard Wolf, Anett Jannasch, Claudia Sperling, Sems‐Malte Tugtekin, Manfred F. Maitz   +7 more
wiley   +1 more source

Distribution of anti-Neu5Gc IgG titers against a mixture of epitopes in NHS II population.

, 2018
Plasma total and inhibitable anti-Neu5Gc IgG levels were quantified by ELISA using wild-type mouse serum as a target that contains naturally occurring Neu5Gc containing sialoglycoproteins epitopes as antigens (N = 46; Table 1).
Annie N. Samraj (5410286), Sandra L. Diaz (375362), Vered Padler-Karavani (375363), Ajit Varki (375367), Dzung Nguyen (5410289), Walter Willett (4016024), Heather Eliassen (5410295), Xi Chen (35903), Kana Wu (318261), Zahra Khedri (2185102), Hai Yu (366836), Christopher J. Gregg (138592), Kimberly A. Bertrand (788938), Robert Luben (153220), Sherilyn Sawyer (5410292), Kay-Tee Khaw (110271)   +15 more
core   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, Volume 45, Issue 4, Page 829-850, July/August 2026.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

Anti-Neu5Gc Antibody Kit Protocol - Flow Cytometry v3 [PDF]

, 2019
Anti-Neu5Gc may be used for staining cells prior to analysis by Flow Cytometry. This kit contains all the essential components needed to identify Neu5Gc on the surface of cells by flow cytometry. Use of the blocking agent (Neu5Gc Assay Blocking Solution) provided in the kit is essential, as commonly used blocking agents invariably contain serum, or ...
openaire   +1 more source