Bacterial flagellin-specific chaperone FliS interacts with anti-sigma factor FlgM. [PDF]
J Bacteriol, 2014 ABSTRACT Flagella are extracellular organelles that propel bacteria. Each flagellum consists of a basal body, a hook, and a filament. The major protein of the filament is flagellin. Induction of flagellin gene expression coincides with secretion of FlgM.
Galeva A +5 more
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The E. coli anti-sigma factor Rsd: studies on the specificity and regulation of its expression. [PDF]
PLoS ONE, 2011 BackgroundAmong the seven different sigma factors in E. coli σ(70) has the highest concentration and affinity for the core RNA polymerase. The E. coli protein Rsd is regarded as an anti-sigma factor, inhibiting σ(70)-dependent transcription at the onset ...
Nina Hofmann, Reinhild Wurm, Rolf Wagner
doaj +5 more sources
Regulatory Role of Anti-Sigma Factor RsbW in Clostridioides difficile Stress Response, Persistence, and Infection. [PDF]
J Bacteriol, 2023 Pathogens like Clostridioides difficile face a range of stresses in the environment and within the host. Alternative transcriptional factors like sigma factor B (σB) enable the bacterium to respond quickly to different stresses.
Cheng JKJ +5 more
europepmc +2 more sources
An Extracytoplasmic Function Sigma/Anti-Sigma Factor System Regulates β-Glucanase Expression in Tannerella forsythia in Response to Fusobacterium nucleatum Sensing. [PDF]
J Bacteriol, 2022 Previous studies have shown that F. nucleatum forms robust biofilms with T. forsythia utilizing glucose from the hydrolysis of β-glucans by T. forsythia β-glucanase, induced by F. nucleatum. In this study, we showed that a regulatory system comprising of
Honma K, Sasaki H, Hamada N, Sharma A.
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Identification and characterization of the cognate anti-sigma factor and specific promoter elements of a T. tengcongensis ECF sigma factor. [PDF]
PLoS ONE, 2012 Extracytoplasmic function (ECF) σ factors, the largest group of alternative σ factors, play important roles in response to environmental stresses. Tt-RpoE1 is annotated as an ECF σ factor in Thermoanaerobacter tengcongensis.
Jingfang Liu +5 more
doaj +5 more sources
An Extracytoplasmic Function Sigma/Anti-Sigma Factor System Regulates Hypochlorous Acid Resistance and Impacts Expression of the Type IV Secretion System in Brucella melitensis. [PDF]
J Bacteriol, 2021 Brucella is a notorious intracellular pathogen that induces chronic infections in animals and humans. To survive and replicate within macrophages, these bacteria require a capacity to withstand oxidative stresses and to express the type IV secretion ...
Li H +7 more
europepmc +2 more sources
DegU-phosphate activates expression of the anti-sigma factor FlgM in Bacillus subtilis. [PDF]
Mol Microbiol, 2011 The bacterial flagellum is a complex molecular machine that is assembled by more than 30 proteins and is rotated to propel cells either through liquids or over solid surfaces.
Hsueh YH +6 more
europepmc +5 more sources
Small RNAs OmrA and OmrB promote class III flagellar gene expression by inhibiting the synthesis of anti-Sigma factor FlgM. [PDF]
RNA Biol, 2020 Bacteria can move by a variety of mechanisms, the best understood being flagella-mediated motility. Flagellar genes are organized in a three-tiered cascade allowing for temporally regulated expression that involves both transcriptional and post ...
Romilly C +3 more
europepmc +2 more sources
Crystal Structures of Streptomyces tsukubaensis sigma factor SigG1 and anti-sigma RsfG.
Journal of Structural Biology, 2023 Transcription of specific genes in bacteria under environmental stress is frequently initiated by extracytoplasmic function (ECF) σ factors. ECFs σ factors harbour two conserved domains, σ2 and σ4, for transcription initiation by recognition of the ...
J. P. Leite +5 more
semanticscholar +3 more sources
A single point mutation in the Listeria monocytogenes ribosomal gene rpsU enables SigB activation independently of the stressosome and the anti-sigma factor antagonist RsbV. [PDF]
Front MicrobiolMicrobial population heterogeneity leads to different stress responses and growth behavior of individual cells in a population. Previously, a point mutation in the rpsU gene (rpsUG50C) encoding ribosomal protein S21 was identified in a Listeria ...
Ma X +6 more
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