Results 11 to 20 of about 3,031 (126)
New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities [PDF]
Marine Drugs, 2011 Four new tetromycin derivatives, tetromycins 1–4 and a previously known one, tetromycin B (5) were isolated from Streptomyces axinellae Pol001T cultivated from the Mediterranean sponge Axinella polypoides.
Ute Hentschel +8 more
doaj +2 more sources
Digalloyl Glycoside: A Potential Inhibitor of Trypanosomal PFK from Euphorbia abyssinica J.F. Gmel
Plants, 2022 Human African trypanosomiasis is an endemic infectious disease caused by Trypanosoma brucei via the bite of tsetse-fly. Most of the drugs used for the treatment, e.g., Suramin, have shown several problems, including the high level of toxicity ...
Seham S. El-Hawary +7 more
doaj +1 more source
The anti‐Trypanosoma activities of medicinal plants: A systematic review of the literature
Veterinary Medicine and Science, 2022 Background The existing drug treatments for trypanosomiases are limited and suffer from shortcomings due to their toxicity and the emergence of resistant parasites.
Shahin Nekoei +5 more
doaj +1 more source
Plants, 2021 Marine halophytes are an outstanding reservoir of natural products and several species have anti-infectious traditional uses. However, reports about their potential use against neglected tropical ailments, such as Chagas disease, are scarce.
Catarina G. Pereira +9 more
doaj +1 more source
Anti–Trypanosomal Effect of Peristrophe bicalyculata Extract on Trypanosoma brucei Brucei–Infected Rats [PDF]
Asian Pacific Journal of Tropical Biomedicine, 2013 Abimbola AM +4 more
exaly +2 more sources
European Journal of Medicinal Chemistry Reports, 2022 Beta-carboline is an indole alkaloid which has been identified as a valuable heterocyclic nucleus in the field of medicinal chemistry. It has different biological activities like antibacterial, anticancer, antifungal, antimalarial, antileishmanial, anti ...
Mahender Thatikayala +6 more
doaj +1 more source
Trypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leads. [PDF]
PLoS Neglected Tropical Diseases, 2011 Trypanosoma brucei, the causative agent of Human African Trypanosomiasis (HAT), expresses two proteins with homology to human glycogen synthase kinase 3β (HsGSK-3) designated TbruGSK-3 short and TbruGSK-3 long.
Richard O Oduor +9 more
doaj +1 more source
Clinical Phytoscience, 2020 Objective The present study investigated the anti-Trypanosoma brucei brucei activity of methanolic extract of Senna occidentalis roots, leaves, stem bark, and seed in vitro and bioactive components of the most active plant part.
Zainab Aliyu Alhafiz +4 more
doaj +1 more source
Chemical characterization of Saudi propolis and its antiparasitic and anticancer properties
Scientific Reports, 2021 Propolis, is a gummy material produced by honey bees from different parts of plants and is enriched with varied biological active compounds like flavonoids, phenolics and phenolic acids with wide applicability in the food, pharmaceutical and cosmetics ...
Samyah Alanazi +4 more
doaj +1 more source
Anti-Trypanosomal Alkaloids from
Natural Product Communications, 2006 From an extract of the stem bark of Xymalos monospora, a bis-benzylisoquinoline alkaloid ( 1 ), three benzylisoquinoline alkaloids (mollinedine, 1-(p-methoxybenzyl)-6,7-methylenedioxyisoquino-line, doryafranine), and an aporphine alkaloid (N ...
Dieudonne Ngamga +7 more
doaj +1 more source