Results 31 to 40 of about 1,940,104 (187)

Anti–trypanosomal effect of Peristrophe bicalyculata extract on Trypanosoma brucei brucei–infected rats [PDF]

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2013
Abimbola AM   +4 more
exaly   +2 more sources

Chemical characterization of Saudi propolis and its antiparasitic and anticancer properties

open access: yesScientific Reports, 2021
Propolis, is a gummy material produced by honey bees from different parts of plants and is enriched with varied biological active compounds like flavonoids, phenolics and phenolic acids with wide applicability in the food, pharmaceutical and cosmetics ...
Samyah Alanazi   +4 more
doaj   +1 more source

Anti-Trypanosomal Alkaloids from

open access: yesNatural Product Communications, 2006
From an extract of the stem bark of Xymalos monospora, a bis-benzylisoquinoline alkaloid ( 1 ), three benzylisoquinoline alkaloids (mollinedine, 1-(p-methoxybenzyl)-6,7-methylenedioxyisoquino-line, doryafranine), and an aporphine alkaloid (N ...
Dieudonne Ngamga   +7 more
doaj   +1 more source

EUCALYPTUS OIL NANOEMULSION: EVALUATION OF IN VITRO ACTIVITY AGAINST TRYPANOSOMA BRUCEI [PDF]

open access: yesZagazig Journal of Pharmaceutical Sciences
Background: Natural products and their secondary metabolites are a good source of pharmacologically active constituents and have been widely developed into modern medicines.
Emmanuel Maduabuchi Uronnachi   +4 more
doaj   +1 more source

Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections

open access: yesMolecules, 2020
Neglected parasitic diseases remain a major public health issue worldwide, especially in tropical and subtropical areas. Human parasite diversity is very large, ranging from protozoa to worms.
Liwen Feng   +12 more
doaj   +1 more source

Establishment of a structure-activity relationship of the 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness [PDF]

open access: yes, 2014
The compound NVP-BEZ235 (1) is a potent inhibitor of human phospoinositide-3-kinases (PI3Ks) and mammalian target of rapamycin (mTOR) that also showed high inhibitory potency against T. brucei cultures. With an eye towards using 1 as a starting point for
Pollastri, Michael P   +10 more
core   +1 more source

Anti-trypanosomal activity and DNA fingerprinting of fifteen Euphorbia species using ISSR and SCoT markers

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2021
Background Euphorbia is the largest genus in family Euphorbiaceae with a great biological and genetic diversity. The anti-trypanosomal activity of the crude extract of 15 Euphorbia species against Trypanosoma brucei brucei was carried out.
Seham S. El-Hawary   +4 more
doaj   +1 more source

Hinokinin, an Emerging Bioactive Lignan

open access: yesMolecules, 2014
Hinokinin is a lignan isolated from several plant species that has been recently investigated in order to establish its biological activities. So far, its cytotoxicity, its anti-inflammatory and antimicrobial activities have been studied.
Maria Carla Marcotullio   +2 more
doaj   +1 more source

DNA fingerprinting of five Tabebuia species with reference to their anti-trypanosomal activity [PDF]

open access: yesPharmaceutical Sciences Asia, 2022
Tabebuia is the largest genus of the Bignoniaceae family, with great importance due to its beautiful decorative flowering trees, as well as, its remarkable biological activities.
Seham El-Hawary   +6 more
doaj   +1 more source

Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Due to toxicity and compliance issues and the emergence of resistance to current medications new drugs for the treatment of Human African Trypanosomiasis are needed. A potential approach to developing novel anti-trypanosomal drugs is by inhibition of the
Eva Doleželová   +9 more
doaj   +1 more source

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