Results 251 to 260 of about 1,082,887 (313)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

Appropriateness and determinants of outpatient antibiotic use among migrants in British Columbia, Canada: a population-based study. [PDF]

open access: yesJAC Antimicrob Resist
Chang CY   +13 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Antibiotic Use Across One Health Sectors in Uganda: Temporal Alignment Between Antibiotic Introduction and Policy Guidance: A Scoping Review and Meta-Analysis

open access: yes
Nabisubi P   +14 more
europepmc   +1 more source

Economics of Antibiotic Resistance [PDF]

open access: yes
Gardner Brown, Ramanan Laxminarayan
core  

Antibiotic Residues in Meat and Animal Feed and Their Association with Antimicrobial Resistance: Evidence from the Kostanay Region, Kazakhstan. [PDF]

open access: yesFoods
Shevchenko P   +8 more
europepmc   +1 more source

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