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2002
The chapter informs about different types of antibiotics, their structure, biosynthesis and their regulation. Industrial cultivation and isolation of antibiotics is described in the chapter. Search for microorganisms producing antibiotics and preparation of high-producing strains is described.
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The chapter informs about different types of antibiotics, their structure, biosynthesis and their regulation. Industrial cultivation and isolation of antibiotics is described in the chapter. Search for microorganisms producing antibiotics and preparation of high-producing strains is described.
openaire +2 more sources
Medical Clinics of North America, 2000
The treatment of severe enterococcal infections based on the currently available antibacterial agents is difficult. The help of the microbiology laboratory for determining MICs, MBCs, and most effective synergistic combinations is crucial. There is a need for good prospective multicenter clinical trials to improve the prognosis of such infections by ...
A, Lefort +3 more
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The treatment of severe enterococcal infections based on the currently available antibacterial agents is difficult. The help of the microbiology laboratory for determining MICs, MBCs, and most effective synergistic combinations is crucial. There is a need for good prospective multicenter clinical trials to improve the prognosis of such infections by ...
A, Lefort +3 more
openaire +2 more sources
How antibiotics cause antibiotic resistance
Drug Discovery Today, 1999Antimicrobial agents are approaching the end of their effectiveness. The prevailing drug development strategy is based on a presumption that results in resistance: that disease can be cured by exploitation of the vulnerabilities in microbial reproduction. Although some did predict the evolution of resistance to such drugs, the mechanisms by which genes
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Folia Microbiologica, 2003
Hybrid antibiotics that do not occur in nature have been obtained by combining structural genes of antibiotic producers. Some of these substances were effective against pathogenic microorganisms resistant against antibiotics produced by the parent strains. The majority of hybrid antibiotics were obtained by combining genes encoding polyketide synthases.
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Hybrid antibiotics that do not occur in nature have been obtained by combining structural genes of antibiotic producers. Some of these substances were effective against pathogenic microorganisms resistant against antibiotics produced by the parent strains. The majority of hybrid antibiotics were obtained by combining genes encoding polyketide synthases.
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The Lancet, 1997
The era of the "classical antibiotic" may be over. The emergence of resistance has seen to that. Yet no truly novel class of antibacterial agent has come on the market in the past 30 years. Currently there is great interest in peptide antibiotics, especially the cationic peptides.
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The era of the "classical antibiotic" may be over. The emergence of resistance has seen to that. Yet no truly novel class of antibacterial agent has come on the market in the past 30 years. Currently there is great interest in peptide antibiotics, especially the cationic peptides.
openaire +2 more sources
Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
Ca-A Cancer Journal for Clinicians, 2021Amila K Nanayakkara +2 more
exaly
Antibiotic resistance in the environment
Nature Reviews Microbiology, 2021D G Joakim Larsson, Carl-Fredrik Flach
exaly