Results 91 to 100 of about 951,869 (260)

Quinoline: A versatile bioactive scaffold and its molecular hybridization

Results in Chemistry
Quinolines have become essential to many drugs, including broad-spectrum antibiotics, antivirus, antitubercular, and antimalarial agents. Owing to their importance in medicinal and pharmaceutic industries, several studies have been conducted to ...
Ibrahim A. Bala, Ohoud F. Al Sharif, Abdullah M. Asiri, Reda M. El-Shishtawy   +3 more
doaj   +1 more source

VanA Mediated Glycopeptide Resistant Enterococcus faecium (GRE) Infection in an Elderly Patient with Chronic Kidney Disease – A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2018
A 66-year-old male patient who is a known case of chronic kidney disease was admitted to the hospital with complaint of seizures. He was uremic and showed signs of encephalopathy.
Martin Jane Esther, PK Rath, R Gopalakrishnan   +2 more
doaj   +1 more source

A New Class of Benzo[b]Thiophene‐1,3,4‐Oxadizole Bearing 1,2,4‐Oxadiazoles as Potent Antimicrobial Targets: Synthesis, Biological Evaluation, Docking, DFT and ADMET Studies

ChemistrySelect, Volume 11, Issue 3, 22 January 2026.
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala, Janardan Sannapaneni, Phani Raja Kanuparthy, Venkata Ramana Singamaneni, Tejeswara Rao Allaka, Pilli Veera Venkata Nanda Kishore   +5 more
wiley   +1 more source

Osteoarticular Tuberculosis: a Secondary Manifestations to Tuberculous Pleural Effusion [PDF]

, 2014
Tuberculosis appears to be increasing throughout the world after years of continuous decline, despite the introduction of effective chemotherapy. This resurgence is related to the increasing number of patients immunocompromised by chemotherapeutic agents
Rumende, C. M. (Cleopas), Setyohadi, B. (Bambang), Singh, G. (Gurmeet)   +2 more
core  

Assessment of Mycobacterium Tuberculosis Sensitive Antibiotics from the Isolation of LJ Media

Indian Journal of Public Health Research & Development, 2020
Pulmonary tuberculosis (PTB) is the major public health air borne disease of India. Socio-economic burden of this disease is also high due to its morbidity and mortality. Patients become resistant to antitubercular antibiotics due to not selecting proper
Zafar Nowshad Wani, Pushpa Yadav, G. Jaiswal, M. Malakar   +3 more
semanticscholar   +1 more source

An Unusual Presentation of Spinal Tuberculosis Masquerading as Pyogenic Meningitis: A Case Report

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
Background Spinal tuberculosis (TB), though accounting for up to 50% of skeletal TB cases, typically presents insidiously with back pain, kyphotic deformity, or neurological deficits. Atypical presentations, including initial neutrophilic pleocytosis in cerebrospinal fluid (CSF), can mimic bacterial meningitis and complicate diagnosis.
Parackrama Karunathilake, Sanjeewa Bowatte, Prabhashini Kumarihamy, Dushantha Madegedara, Madushika Gunathilake, Beruni Narmada, Takanobu Hirosawa   +6 more
wiley   +1 more source

Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Bacillus Calmette–Guérin (BCG): A Steroid‐Sparing Strategy in a Patient Awaiting Cardiac Surgery—A Case Report

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
We report a case of hemophagocytic lymphohistiocytosis (HLH) secondary to disseminated Bacillus Calmette–Guérin (BCG) infection in an 80‐year‐old man treated with intravesical BCG for non–muscle‐invasive bladder cancer. The patient presented with several weeks of constitutional symptoms including night sweats, fatigue, weight loss, confusion, and ...
Kaitlin Quinlan, Tyler MacDonald, Terence C. Wuerz, Ryan Zarychanski, Yoshito Nishimura   +4 more
wiley   +1 more source

Antimicrobial resistance from a One Health perspective in Zambia: a systematic review

Antimicrobial Resistance and Infection Control, 2023
Background Antimicrobial resistance (AMR) is widely acknowledged as a global health problem, yet its extent is not well evaluated, especially in low-middle income countries.
Avis A. Nowbuth, Akwi W. Asombang, Nkengeh N. Tazinkeng, Opeoluwa Y. Makinde, Lincoln R. Sheets   +4 more
doaj   +1 more source

Exploring the Natural Products Atlas (NPAtlas) Database for Hunting Prospective Irreversible Covalent DprE1 Inhibitors With Antitubercular Activity: An Integrated In-Silico Approach

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
As the second most deadly infectious disease worldwide after COVID‐19, tuberculosis (TB) remains a pressing global health issue, further aggravated by multidrug‐resistant TB (MDR‐TB) and extensively drug‐resistant TB (XDR‐TB) strains. There is an urgent need to identify new anti‐TB treatments and novel therapeutics to confront drug resistance.
Mahmoud A. A. Ibrahim, Doaa G. M. Mahmoud, Sherif S. Ebada, Peter A. Sidhom, Gamal A. H. Mekhemer, Mohamed-Elamir F. Hegazy, Yanshuo Han, Tarad Abalkhail, Rajib Chowdhury   +8 more
wiley   +1 more source

Drug-Induced Musculoskeletal Syndromes and Soft-Tissue Rheumatism

Indian Journal of Rheumatology, 2019
Drug-induced musculoskeletal syndromes represent a broad clinical spectrum, ranging from asymptomatic biological abnormalities to severe organ-threatening manifestations. Many drugs have been implicated in inducing rheumatological adverse events.
Rudra Prosad Goswami, Parasar Ghosh
doaj   +1 more source