Results 101 to 110 of about 1,877,361 (339)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Antioxidant Properties of Water-Soluble Polysaccharides and Ethanolic Extracts of Xylotrophic Basidiomycetes Mycelium

Антибиотики и Химиотерапия, 2020
The present study was conducted to investigate the antioxidant properties of water-soluble polysaccharides and ethanolic extracts of submerged mycelium of basidiomycetes Ganoderma lucidum (Curtis) P.
N. R. Almyasheva, M. S. Yarina, A. V. Golyshkin, B. R. Dzhavakhyan, L. M. Krasnopolskaya   +4 more
doaj  

Prevalence and predictors of postdischarge antibiotic use following mastectomy [PDF]

, 2017
OBJECTIVESurvey results suggest that prolonged administration of prophylactic antibiotics is common after mastectomy with reconstruction. We determined utilization, predictors, and outcomes of postdischarge prophylactic antibiotics after mastectomy with ...
Fraser, Victoria J, Nickel, Katelin B, Olsen, Margaret A, Wallace, Anna E, Warren, David K   +4 more
core   +2 more sources

Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens

, 2021
Lei Li, Bimal Koirala, Yözen Hernández, Logan W. MacIntyre, Melinda A. Ternei, Riccardo Russo, Sean F. Brady   +6 more
openalex   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Design of Novel Carboxamides of Eremomycin and Vancomycin with 4- or 3-Amino Methyl Phenyl Boric Acid and Their Investigation

Антибиотики и Химиотерапия, 2020
Amidation of the end carboxyl group of eremomycin and vancomycin by pinacolinic 4- or 3-amino methyl phenyl boron acids esters in the presence of the condensing reagent PyBOP resulted in formation of novel carboxamides of the antibiotics (IIIa-VIa ...
E. N. Bychkova, A. M. Korolev, E. N. Olsufyeva, E. P. Mirchink, E. B. Isakova   +4 more
doaj  

Prevalence of fosfomycin resistance and mutations in murA, glpT, and uhpT in methicillin-resistant Staphylococcus aureus strains isolated from blood and cerebrospinal fluid samples

Frontiers in Microbiology, 2016
In China, fosfomycin alone or in combination with other antibiotics is commonly used in the treatment of infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Although fosfomycin-resistant S.
Zhuyingjie eFu, Ying eMa, Chunhui eChen, Yan eGuo, Fupin eHu, Yang eLiu, Xiaogang eXu, Minggui eWang   +7 more
doaj   +1 more source

Trends and Racial/Ethnic Disparities in Antibiotic Prescribing Practices of Dentists in The United States [PDF]

, 2018
Objective The aim of this study was to examine trends and racial/ethnic disparities in antibiotic prescribing practices of dentists in the United States. Methods The US Medical Expenditure Panel Survey data for 1996‐2013 was analyzed.
Okunseri, Christopher, Okunseri, Elaye, Steinmetz, C. N., Szabo, Aniko, Zheng, C.   +4 more
core   +1 more source

FORMATION OF THE INTESTINAL MICROBIOTA OF PREMATURE NEWBORNS WHO RECEIVED AND DID NOT RECEIVE A COURSE OF ANTIBIOTICS AND PROBIOTICS

, 2023

openalex   +1 more source