Results 51 to 60 of about 60,579 (143)

In vitro detection of canine anti-human antibodies following intratumoral injection of the hu14.18-IL2 immunocytokine in spontaneous canine melanoma.

PLoS ONE
BackgroundCanine and human malignant melanoma are naturally occurring cancers with many similarities, making the dog an important parallel patient population to study both diseases.
Andrew T Kosharek, Cindy L Zuleger, William S Glass, Jens Eickhoff, Paul M Sondel, David M Vail, Mark R Albertini   +6 more
doaj   +1 more source

The study of pharmacodynamics of a medicine based on humanized monoclonal antibodies against IL-17 in rabbit model of antigen-induced arthritis

Биопрепараты: Профилактика, диагностика, лечение, 2018
The present article contains scientific data on the assessment of specific activity of therapeutic humanized monoclonal antibodies against IL-17 in rabbit model of antigen-induced arthritis.
A. A. Nedorubov, A. V. Grachev, M. A. Varavko, E. L. Morozova   +3 more
doaj  

Mepolizumab for hypereosinophilic syndrome: effectiveness and safety from real-world evidence

Frontiers in Immunology
Hypereosinophilic syndrome (HES) is a rare condition characterized by elevated eosinophil levels and related symptoms of eosinophil-mediated organ damage. We reviewed the effectiveness and safety of mepolizumab for the treatment of HES.
Elvira Mora, María Laura Fox, María Laura Fox, Angelina Lemes, Beatriz Velasco, Jesús María Hernández-Rivas, Jesús María Hernández-Rivas   +6 more
doaj   +1 more source

Unraveling Alzheimer’s: the promise of aducanumab, lecanemab, and donanemab

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Alzheimer’s disease (AD) is a neurodegenerative condition that causes cognitive decline, memory loss, and reduced personal autonomy. The pathology of AD involves the aggregation of abnormal brain proteins, specifically beta-amyloid plaques and tau ...
Taha Basit Ameen, Syeda Naveera Kashif, Syed Muhammad Iraj Abbas, Kulsoom Babar, Syed Muhammad Sinaan Ali, Abdul Raheem   +5 more
doaj   +1 more source

Antibodies to watch in 2026. [PDF]

MAbs
Crescioli S, Kaplon H, Chenoweth A, Hsu YS, Pinto K, Kapoor V, Reichert JM.   +6 more
europepmc   +1 more source

A novel TM4SF4-targeting therapeutic antibody candidate with antitumor activity by blocking IGF1R and CD44 signaling and downregulating PD-L1 and B7-H4. [PDF]

Theranostics
Kim RK, Heo CK, Choi MJ, Kahm YJ, Kim MK, Lee M, Lee JY, Park H, Jung U, Shin BC, Kim BJ, Kim SC, Cho EW, Ryu CJ, Kim IG.   +14 more
europepmc   +1 more source

Comparison of chimeric mouse-human and humanized anti-CD25 monoclonal antibodies for steroid-refractory acute graft-versus-host disease. [PDF]

Front Immunol
Zheng X, Zhou Y, Zheng Y, Lu N, Cao Y, Zhai W, Wei J, Yang D, Zhang R, Pang A, Feng S, Han M, Jiang E, Chen X.   +13 more
europepmc   +1 more source

Blockade of CD155 and CD276 by Monoclonal Antibodies Fosters Immune Tolerance and Promotes Stable Engraftment of iPSC-Derived Islets in Allogeneic Humanized Mice. [PDF]

Transpl Int
Siracusano G, Deambrogio F, Sordi V, Malnati M, Piemonti L, Chimienti R.   +5 more
europepmc   +1 more source

Oral Bioavailability of Monoclonal Antibody. [PDF]

Pharmaceutics
Verma A, Wu S, Shah DK.
europepmc   +1 more source

Development of a humanized anti-fibrin monoclonal antibody for the treatment of neuroinflammatory and retinal diseases. [PDF]

J Neuroinflammation
Kantor AB, Rickert M, Cheng H, Flanagan K, Salgotra V, Suppahia A, Ryu JK, Widboom PF, Warfield JR, Akassoglou K, Stavenhagen JB.   +10 more
europepmc   +1 more source