A bioelectronic sensor integrating 2D cell membranes with organic microelectrode arrays enables detection of SARS‐CoV‐2 fusion pathways. Natively‐expressed viral receptors promote monitoring of viral entry and screening of antibody‐based inhibitors.
Zixuan Lu +17 more
wiley +1 more source
Therapeutic innovations in triple negative breast cancer: integrating molecular targeting and monoclonal antibody strategies. [PDF]
Mir PA +6 more
europepmc +1 more source
A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening
A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder +3 more
wiley +1 more source
Dissecting antibody-dependent enhancement modulation by Fc-modified cross-neutralizing human monoclonal antibody. [PDF]
Injampa S +8 more
europepmc +1 more source
A rapid glass‐substrate 3D microfabrication method creates anatomically accurate carotid artery‐on‐a‐chip models from stroke patient scans in 2 h. These miniaturized devices replicate patient‐specific blood vessel geometry and flow patterns, enabling real‐time imaging of clot formation under controlled injury.
Yunduo Charles Zhao +14 more
wiley +1 more source
Targeting Amyloid-β Proteins as Potential Alzheimer's Disease Therapeutics: Anti-Amyloid Drug Discovery, Emerging Therapeutics, Clinical Trials and Implications for Public Health. [PDF]
Abduljawad AA +9 more
europepmc +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Cure of experimental <i>Trypanosoma vivax</i> infection with a single dose of an unmodified antibody-based drug targeting the invariant flagellum cell surface protein IFX. [PDF]
Autheman D +6 more
europepmc +1 more source
Optoacoustic‐Guided Magnetic Microrobot Platform for Precision Drug Delivery
Optoacoustically guided FePt@ZIF‐8‐based microrobots are designed with high drug loading capacity, controllable locomotion, and deep‐tissue imaging capability. By integrating navigation, drug release, and real‐time monitoring into a single platform, they provide a versatile tool for precise intervention, opening new possibilities for treating ...
Fan Wang +12 more
wiley +1 more source

