Results 221 to 230 of about 2,156,166 (288)

Monoclonal antibody against canine distemper virus H protein potently neutralizes the giant panda-derived strain. [PDF]

AMB Express
Li Y, Wu J, Li J, Zeng J, Li L, Su X, Wang J, Xia X, Hou R, Feng N, Liu S.   +10 more
europepmc   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Inducible immortalized Dendritic Cells enable antigen-specific antibody production in a murine in vitro Immunization model. [PDF]

PLoS One
Egert J, Maier N, Micheel B, Hanack K.
europepmc   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Glycation Product Synthesized in Anhydrous Conditions Mimics an Epitope in Epithelial and Mesenchymal Tissues. [PDF]

Biomedicines
Czech M, Gamian E, Kochman A, Woźniak M, Jaskuła E, Ziółkowski P, Gamian A.   +6 more
europepmc   +1 more source

Respiratory syncytial virus prevention in infants and equity in Latin America and the Caribbean: from evidence to action. [PDF]

Lancet Reg Health Am
Avila-Aguero ML, Falleiros-Arlant LH, Brea J, Espinal C, Muñoz F.   +4 more
europepmc   +1 more source

Burden of severe asthma in Italy: Patients treated with versus eligible for monoclonal antibodies in a large real-world study. [PDF]

J Int Med Res
Dondi L, Ronconi G, Calabria S, Dell'Anno I, Dondi L, Addesi A, Esposito I, Canonica GW, Martini N, Piccinni C.   +9 more
europepmc   +1 more source