Results 241 to 250 of about 2,156,166 (288)
Some of the next articles are maybe not open access.
New England Journal of Medicine, 1981
Serologic reagents have played an important role in the diagnosis, treatment, and epidemiology of infectious diseases. A new technology has been developed for generating homogeneous antibodies that can be produced in large amounts and are available indefinitely. This technique promises to increase the reliability and sensitivity of immunoassays and may
M D, Scharff, S, Roberts, P, Thammana
openaire +4 more sources
Serologic reagents have played an important role in the diagnosis, treatment, and epidemiology of infectious diseases. A new technology has been developed for generating homogeneous antibodies that can be produced in large amounts and are available indefinitely. This technique promises to increase the reliability and sensitivity of immunoassays and may
M D, Scharff, S, Roberts, P, Thammana
openaire +4 more sources
2008
Monoclonal antibodies (mabs) are powerful tools for the quantification, detection, and targeting of specific molecules. Allergen-specific mabs are important for the quantification of major allergens in allergen preparations used for allergen-specific immunotherapy and allergy diagnosis.
Helga, Kahlert, Oliver, Cromwell
openaire +2 more sources
Monoclonal antibodies (mabs) are powerful tools for the quantification, detection, and targeting of specific molecules. Allergen-specific mabs are important for the quantification of major allergens in allergen preparations used for allergen-specific immunotherapy and allergy diagnosis.
Helga, Kahlert, Oliver, Cromwell
openaire +2 more sources
Molecular and Cellular Biochemistry, 1984
The technology for the production of murine monoclonal antibodies has been refined enormously since its introduction in 1975. However, the technology for generating human monoclonal antibodies has only recently come into its own. In this review, three currently available approaches to the production of human monoclonal antibodies are described.
S P, Cole +4 more
openaire +4 more sources
The technology for the production of murine monoclonal antibodies has been refined enormously since its introduction in 1975. However, the technology for generating human monoclonal antibodies has only recently come into its own. In this review, three currently available approaches to the production of human monoclonal antibodies are described.
S P, Cole +4 more
openaire +4 more sources
Revue Francaise de Transfusion et Immuno-hématologie, 1988
The Rh antibodies were studied by manual serological techniques (see Daniels' report on Kell related antigens), using human red cells of common and rare Rh phenotypes in an attempt to identify their specificity and/or usefulness as reagents. The report is divided into 3 sections : section I anti-D antibodies, section II other Rh specifities, section ...
P, Tippett, C, Lomas
openaire +2 more sources
The Rh antibodies were studied by manual serological techniques (see Daniels' report on Kell related antigens), using human red cells of common and rare Rh phenotypes in an attempt to identify their specificity and/or usefulness as reagents. The report is divided into 3 sections : section I anti-D antibodies, section II other Rh specifities, section ...
P, Tippett, C, Lomas
openaire +2 more sources
Generating Monoclonal Antibodies
Cold Spring Harbor Protocols, 2022Antibodies that are produced by hybridomas are known as monoclonal antibodies. Here we introduce methods for generating and screening monoclonal antibodies, including developing the screening procedure and producing hybridomas.
openaire +2 more sources
Frontiers in Bioscience, 2006
The concept of targeted therapy was conceived through increased understanding of the biological pathways involved in the pathogenesis of cancer and subsequently identification of the most appropriate antigens to target. Monoclonal antibody therapy harnesses host defense mechanisms through activation of the antibody dependent cytotoxic pathway and ...
Deirdre, O'Mahony, Michael R, Bishop
openaire +2 more sources
The concept of targeted therapy was conceived through increased understanding of the biological pathways involved in the pathogenesis of cancer and subsequently identification of the most appropriate antigens to target. Monoclonal antibody therapy harnesses host defense mechanisms through activation of the antibody dependent cytotoxic pathway and ...
Deirdre, O'Mahony, Michael R, Bishop
openaire +2 more sources
Monoclonal Antibodies: A Review.
Current Clinical Pharmacology, 2017BACKGROUND Over the last three decades, monoclonal antibodies (MAbs) have made a striking transformation from scientific tools to powerful human therapeutics.
Surjit Singh +6 more
semanticscholar +1 more source
Multispecific monoclonal antibodies
Immunology Today, 1986Monoclonal antibodies are frequently shown to participate in unexpected cross reactions involving two apparently dissimilar antigens. This can be attributed either to partial epitope identity or to irrelevant interactions involving additional binding capacity of the antibody.
D, Isenberg, C, Dudeney, W, Williams
openaire +4 more sources
ANTIRETINOBLASTOMA MONOCLONAL ANTIBODIES
Retina, 1983Mouse-mouse somatic hybridization techniques were used to produce monoclonal antibodies directed towards antigen expressed on retinoblastoma-derived tissue culture cell lines. Four monoclonal antibodies were produced with varying avidity which were reactive against allogeneic retinoblastoma-associated antigens.
D H, Char +4 more
openaire +2 more sources