Results 41 to 50 of about 2,469,529 (358)

Induction of high affinity monoclonal antibodies against SARS-CoV-2 variant infection using a DNA prime-protein boost strategy

Journal of Biomedical Science, 2022
Background Calls for the coronavirus to be treated as an endemic illness, such as the flu, are increasing. After achieving high coverage of COVID-19 vaccination, therapeutic drugs have become important for future SARS-CoV-2 variant outbreaks.
Chen-Yi Chiang, Mei-Yu Chen, Chia-Wei Hsu, Chia-Yeh Liu, Yu-Wen Tsai, Hung-Chun Liao, Jia-Ying Yan, Zih-Shiuan Chuang, Hsin-I. Wang, Chien-Hsiung Pan, Chia-Yi Yu, Guann-Yi Yu, Ching-Len Liao, Shih-Jen Liu, Hsin-Wei Chen   +14 more
doaj   +1 more source

Monoclonal antibodies against human CD34 antigens do not cross-react with ovine umbilical cord blood cells [PDF]

, 2010
CD34 is a cell surface glycoprotein expressed by hematopoietic progenitors and endothelial cells. It is widely used in the clinic for isolation of human hematopoietic stem cells.
Antuofermo, Elisabetta, Bonelli, Piero, Dattena, Maria, Manetti, Roberto, Nicolussi, Paola   +4 more
core   +2 more sources

Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles

Biosafety and Health, 2022
The coronavirus disease 2019 (COVID-19) is still causing a wide range of infections and deaths due to the high variability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Sheng Wang, Lizhen Liu, Can Wang, Ziqiang Wang, Xuhua Duan, Gang Chen, Hu Zhou, Hong Shao   +7 more
doaj  

CD20-targeting in B-cell malignancies: novel prospects for antibodies and combination therapies [PDF]

, 2016
Expression of CD20 antigen by the most of transformed B cells is believed to be the driving force for targeting this molecule by using anti-CD20 monoclonal antibodies. While it is true that most lymphoma/leukemia patients can be cured, these regimens are
Ahmadzadeh, V., Farajnia, S., Safdari, Y.   +2 more
core   +1 more source

Dependence of endothelial cell growth on substrate-bound fibronectin [PDF]

, 1992
A better understanding of the mechanism of adhesion, spreading and proliferation of human endothelial cells (HEC) on polymeric surfaces may lead to the development of vascular prostheses which allow the formation of an endothelial lining on the luminal ...
Aken, W.G. van, Bantjes, A., Beugeling, T., Dekker, A., Feijen, J., Mourik, J.A. van, Poot, A., Spijkers, J.   +7 more
core   +2 more sources

Modelling Bi-specific Antibodies in Aqueous Solution [PDF]

arXiv, 2023
This study presents theoretical results for physico-chemical properties of system of molecules modeling bi-specific antibodies, such as, dual-variable-domain monoclonal antibodies (DVD-Ig) and Fabs-In-Tandem Immunoglobulin (FIT-Ig). These molecules are representatives of the engineered proteins that combine the function and specificity of two ...
arxiv  

The Use of Biotechnological Drugs in Pediatrics on the Example of Monoclonal Antibodies: Clinical Pharmacology View

Педиатрическая фармакология, 2021
The article reviews monoclonal antibodies, its structure, classifications, pharmacodynamics, pharmacokinetics, and adverse effects. There are examples for each section.
Alexey S. Kolbin, Liudmila I. Yemelyanova   +1 more
doaj   +1 more source

Characterization of protective and non-protective surface membrane carbohydrate epitopes of Schistosoma mansoni

Memorias do Instituto Oswaldo Cruz, 1987
We have produced a number of monoclonal antibodies, protective and non-protective, which recognize a complex of schistosomula antigens, including the 38 kDa antigen. Eight different protective and non-protective monoclonal antibodies, varying in isotypes,
Albert I. Ko, Donald A. Harn
doaj   +1 more source

Monoclonal antibodies and antibody fragments: state of the art and future perspectives in the treatment of non-haematological tumors [PDF]

, 2011
Introduction: The use of monoclonal antibodies is one of the strategies for targeting the specific key points of the main pathways of cancer growth and survival, but only a few antibodies have offered a clear clinical benefit in the treatment of non ...
BAZAN, Viviana, BRONTE, Giuseppe, COCORULLO, Gianfranco, DI FEDE, Gaetana, GULOTTA, Gaspare, RIZZO, Sergio, Rolfo Cervetto, C, RUSSO, Antonio   +7 more
core   +1 more source

European headache federation guideline on the use of monoclonal antibodies acting on the calcitonin gene related peptide or its receptor for migraine prevention

The Journal of Headache and Pain, 2019
Background and aimMonoclonal antibodies acting on the calcitonin gene-related peptide or on its receptor are new drugs to prevent migraine. Four monoclonal antibodies have been developed: one targeting the calcitonin gene-related peptide receptor ...
S. Sacco, L. Bendtsen, M. Ashina, U. Reuter, G. Terwindt, D. Mitsikostas, P. Martelletti   +6 more
semanticscholar   +1 more source