Results 301 to 310 of about 5,065,448 (337)

Seroprevalence of Anti-SARS-CoV-2 Antibodies in Cats during Five Waves of COVID-19 Epidemic in Thailand and Correlation with Human Outbreaks [PDF]

Suporn Thongyuan, Jeeraphong Thanongsaksrikul, Potjanee Srimanote, Wallaya Phongphaew, Piyaporn Eiamcharoen, Naris Thengchaisri, Angela M. Bosco‐Lauth, Nicola Decaro, Rungrueang Yodsheewan   +8 more
openalex   +1 more source

SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High‐Grade Gliomas: A Multicenter, Open‐Label Phase I Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang, Shenglan Li, Liang Wang, Qianxue Chen, Weiguo Hu, Ting Lei, Ying Mao, Jing Zhang, Xiaojun Xiang, Qiming Wang, Zhengwen He, Tao Sun, Yulei Wang, Mengqian Huang, Rong Zhang, Feng Chen, Wenbin Li   +16 more
wiley   +1 more source

Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia. [PDF]

Front Immunol
Xu X, Baal N, Rick M, Chen D, Liang H, Ye X, Xia W, Ren H, Xu Y, Fu Y, Bein G, Santoso S.   +11 more
europepmc   +1 more source

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin, Gregory Sahagian, Marc H. Feinberg, C. Andrew Stewart, Christopher M. Jewell, Metin Kurtoglu, Miloš D. Miljković, Tuan Vu, Tahseen Mozaffar, James F. Howard Jr, the MG‐001 Study Group   +10 more
wiley   +1 more source

Quality Assessment of Therapeutic Drug Monitoring Assays of Therapeutic Antibodies Across Europe: An Update. [PDF]

Basic Clin Pharmacol Toxicol
Bluett J, Rumano M, Martínez Becerra MJ, Loeff F, Itik M, Ternant D, Desvignes C, Mulleman D, Skrede S.   +8 more
europepmc   +1 more source

Cross reactivity within pneumococcal serogroups 6 and 15 following adult vaccination with pneumococcal conjugate vaccine V116. [PDF]

Commun Med (Lond)
Li J, Platt HL, Hu W, Xu W, Chapman TJ, Nolan KM, Hartzel J, Buchwald UK.   +7 more
europepmc   +1 more source

Immunological consequences of past transfusions in kidney transplant candidates: A focus on anti-HLA antibody formation. [PDF]

Hematol Transfus Cell Ther
Perić T, Vojvodić S.
europepmc   +1 more source

ANA-positive versus ANA-negative Antiphospholipid Antibody-positive Patients: Results from the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Clinical Database and Repository (“Registry”)

Irene Cecchi, Massimo Radin, Silvia Grazietta Foddai, Alice Barinotti, Danieli Andrade, Maria G. Tektonidou, Vittorio Pengo, Guillermo Ruiz‐Irastorza, H. Michael Belmont, C. López-Pedrera, Paul R. Fortin, Maria Gerosa, Guilherme Ramires de Jesús, Tatsuya Atsumi, Lanlan Ji, Maria Efthymiou, D. Ware Branch, Cecilia Nalli, Esther Rodriguez‐Almaraz, Michelle Petri, Ricard Cervera, Jason S. Knight, Bahar Artim‐Esen, Rohan Willis, María Laura Bertolaccini, Hannah Cohen, Doruk Erkan, Savino Sciascia   +27 more
openalex   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source