Results 301 to 310 of about 3,666,403 (333)
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Antibodies in proteomics I: generating antibodies
Trends in Biotechnology, 2003The explosion in genome sequencing, and in subsequent DNA array experiments, has provided extensive information on gene sequence, organization and expression. This has resulted in a desire to perform similarly broad experiments on all the proteins encoded by a genome.
BRADBURY A. +9 more
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Antibody and antibody derivatives as cancer therapeutics
WIREs Nanomedicine and Nanobiotechnology, 2019Antibodies are an important class of therapeutic for treating a wide range of diseases. These versatile macromolecules can be engineered to target many different antigens and to utilize several mechanisms of action to produce a pharmacological effect. The most common antibody platform used for therapeutics is immunoglobulin G (IgG). Advances in proteinā
Keith J, Arlotta, Shawn C, Owen
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Antiphospholipid antibodies and the antiphospholipid antibody syndrome
Drugs of Today, 2000The antiphospholipid antibody syndrome is a multisystem disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia and recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with this ...
G T, Nahass, S L, Jensen
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Production of antibodies and antibody fragments in plants
Vaccine, 2001Our current knowledge allows the generation of transgenic plants that efficiently produce heterologous proteins from plant, bacterial, fungal or animal origin. Among all types of recombinant proteins, antibodies are particularly attractive because of their ability to specifically recognize and bind virtually any type of antigen.
Peeters, Koen +4 more
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From antibodies to sperm to antibodies in transplantation
Urology, 1998a) To assess the use of "panning" procedures for the detection of antibodies to sperm. b) To develop and use human monoclonal antibodies for the analysis of human transplantation antigens."Panning" assays were developed. The procedures and their use in the analysis of mouse monoclonal antibodies to human sperm are described.
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Antiacetylcholinesterase antibodies: Enzyme antibodies interaction
Pharmacological Research Communications, 1981Summary Erythrocyte acetylcholinesterase activity of rabbits was significantly increased over control levels by immunization with acetylcholinesterase from the electric organ of the electric eel. The increase of enzyme activity and that of anti-acetylcholinesterase antibodies had the same time course, reaching a maximum level on the 35th day.
D, Pedretti +3 more
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Antiphospholipid antibody and antiphospholipid antibody syndrome
Current Opinion in Rheumatology, 1991New details have been added to the description of the antiphospholipid antibody syndrome. These include quantitation of risk of stroke; delineation of an associated acute occlusive vasculopathy syndrome, including its pathology; increased awareness of the association of adrenal insufficiency with antiphospholipid antibody; new demonstration of ...
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Veterinary Microbiology, 2006
Herpesviruses have developed different tools to thwart efficient antibody-dependent neutralisation and lysis of virions and elimination of infected cells. This overview will briefly summarize different of these tools, including (i) viral Fc receptors and the resulting process of antibody bridging, (ii) internalization of individual viral proteins and ...
Herman W, Favoreel +4 more
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Herpesviruses have developed different tools to thwart efficient antibody-dependent neutralisation and lysis of virions and elimination of infected cells. This overview will briefly summarize different of these tools, including (i) viral Fc receptors and the resulting process of antibody bridging, (ii) internalization of individual viral proteins and ...
Herman W, Favoreel +4 more
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Recombinant Antibodies for the Generation of Antibody Arrays
2011Affinity proteomics, mainly represented by antibody microarrays, has in recent years been established as a powerful tool for high-throughput (disease) proteomics. The technology can be used to generate detailed protein expression profiles, or protein maps, of focused set of proteins in crude proteomes and potentially even high-resolution portraits of ...
Carl A K, Borrebaeck, Christer, Wingren
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Antiphospholipid antibodies and the antiphospholipid antibody syndrome
Journal of the American Academy of Dermatology, 1997The antiphospholipid antibody syndrome is a multiple-system disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia, or recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with ...
openaire +2 more sources

