Development and Validation of Cell-Based Bioassay for the Detection of Neutralizing Antibodies to Ocrelizumab in Human Serum Using Antibody-Dependent Cell-Mediated Cytotoxicity Test in a Reporter Cell Line Expressing FcγRIIIa. [PDF]
Strizhakova O +7 more
europepmc +1 more source
Oncolytic Herpes Virus G47Δ Potentiates ADCC-Inducing Molecular Targeted Therapy via Coordinated Activation of Innate and Adaptive Immune Responses. [PDF]
Nagatomo T +4 more
europepmc +1 more source
Fc effector functions in RNA viral infections: mechanisms of antiviral immunity and implications for vaccine design. [PDF]
Zhang J +9 more
europepmc +1 more source
Comparison of four different in vitro assays for prediction of potential RBC antibody clinical significance. [PDF]
Noa YR +6 more
europepmc +1 more source
A fully human afucosylated anti-GARP antibody PBA-0111 drives anti-tumor immunity through combined ADCC induction and TGF-β1 pathway blockade. [PDF]
Spee P +25 more
europepmc +1 more source
A mathematical model of antibody-dependent cellular cytotoxicity (ADCC) [PDF]
Immunotherapies exploit the immune system to target and kill cancer cells, while sparing healthy tissue. Antibody therapies, an important class of immunotherapies, involve the binding to specific antigens on the surface of the tumour cells of antibodies that activate natural killer (NK) cells to kill the tumour cells.
David Gavaghan, Helen Byrne
exaly +3 more sources

