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Immune escape from HIV-specific antibody-dependent cellular cytotoxicity (ADCC) pressure [PDF]
Effective immunity to HIV is poorly understood. In particular, a role for antibody-dependent cellular cytotoxicity (ADCC) in controlling HIV is controversial. We hypothesized that significant pressure from HIV-specific ADCC would result in immune-escape variants.
Ivan Stratov, Stephen J. Kent, Amy Chung
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Antibody-Dependent Cellular Cytotoxicity (ADCC)
2014Louis M Weiner, Joseph C Murray
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Interspecies Variability in Antibody-Dependent Cellular Cytotoxicity (ADCC)
The Journal of Immunology, 1974Abstract Lymphoid effector cells and antisera from several species were evaluated in allogeneic or xenogeneic test systems for their ability to mediate the cytolysis of radiochromium-labeled target cells, antibody-dependent cellular cytotoxicity (ADCC).
J, Zighelboim, R P, Gale
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Journal of Immunological Methods, 1985
A method is described for measuring antibody-dependent cellular cytotoxicity (ADCC) of mononuclear cells from human peripheral blood using an established murine cell line and commercially prepared antisera. The test utilizes a standard 51Cr release technique.
Joseph Sonnabend +2 more
exaly +3 more sources
A method is described for measuring antibody-dependent cellular cytotoxicity (ADCC) of mononuclear cells from human peripheral blood using an established murine cell line and commercially prepared antisera. The test utilizes a standard 51Cr release technique.
Joseph Sonnabend +2 more
exaly +3 more sources
Enhancement of Antibody Dependent Cellular Cytotoxicity (ADCC) by Combination of Cytokines
Hybridoma, 1999Monoclonal antibodies (MAb) specific for tumor-associated antigens (TAA) can induce an immunological cellular attack of tumor cells by a process termed antibody dependent cellular cytotoxicity (ADCC). Cytokines may augment ADCC by direct activation of immune cells or by enhancement of TAA on tumor cells.
D, Flieger +7 more
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The involvement of the cytoskeleton during antibody-dependent cellular cytotoxicity (ADCC)
Cell Biology International Reports, 1984The mechanism of initiation of antibody-dependent cellular cytotoxicity (ADCC) was analyzed using a model system consisting of sensitized chicken red blood cells (ChRBC) as targets and non-immunized Balb/c mouse splenocytes as effectors. Using a 51Cr release assay in parallel with electron and light microscopic observations, we were able to correlate ...
K J, Balazovich +2 more
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Effect of human adenovirus on antibody-dependent cellular cytotoxicity (ADCC) in chickens
Cellular Immunology, 1982The influence of human adenovirus type 6 on antibody-dependent cellular cytotoxicity (ADCC) in chickens has been investigated. The cytotoxic effect of peripheral blood mono-nuclear cells of chickens was studied on sheep red blood cells (SRBC) coated with chicken anti-SRBC serum. Cytotoxicity was estimated using a 51Cr release assay system.
Y, Mándi, M, Bakay, I, Béládi
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Journal of Hepatology, 2001
Recent observations suggest that natural killer (NK) cell activity might be impaired in chronic hepatitis C. However, to date antibody-dependent cellular cytotoxicity (ADCC) has not been studied in chronic hepatitis C in detail.Therefore, we investigated spontaneous and cytokine-induced (interleukin-2 and interferon-gamma) natural cytotoxicity and ADCC
Ulrich Spengler +2 more
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Recent observations suggest that natural killer (NK) cell activity might be impaired in chronic hepatitis C. However, to date antibody-dependent cellular cytotoxicity (ADCC) has not been studied in chronic hepatitis C in detail.Therefore, we investigated spontaneous and cytokine-induced (interleukin-2 and interferon-gamma) natural cytotoxicity and ADCC
Ulrich Spengler +2 more
exaly +3 more sources
A comparison of human lymphoid cells in antibody-dependent cellular cytotoxicity (ADCC)
Clinical Immunology and Immunopathology, 1975Abstract Human lymphoid cells from normal donors, hospitalized controls, patients with chronic lymphocytic leukemia (CLL), and lymphoblastoid cell lines (LCLs) were examined for their ability to act as effector cells in antibody-dependent cellular cytotoxicity (ADCC).
R P, Gale +3 more
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Research in Experimental Medicine, 1992
The purpose of this study was to determine the effects that specific inhibition of arachidonic acid (AA) metabolism has on the antibody-dependent cellular cytotoxicity (ADCC) of murine spleen cells. The action of three inhibitors of the lipoxygenase (LO) pathway--nordihydroguaiaretic acid (NDGA), esculetin (Es), and phenanthroline (Phe)--was compared ...
J, Hernández-Godoy +4 more
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The purpose of this study was to determine the effects that specific inhibition of arachidonic acid (AA) metabolism has on the antibody-dependent cellular cytotoxicity (ADCC) of murine spleen cells. The action of three inhibitors of the lipoxygenase (LO) pathway--nordihydroguaiaretic acid (NDGA), esculetin (Es), and phenanthroline (Phe)--was compared ...
J, Hernández-Godoy +4 more
openaire +2 more sources

